ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-9.PDB
Scoring matrix: RVS167_FYN-SSH-9_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.52
Foldx random average score for Saccharomyces cerevisiae: 10.231

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181364
Proteins after random average filtering: 5078
 Total fragments: 1075016
Proteins after disorder filtering: 3175
 Total fragments: 53604
Proteins after pattern filtering: 1570
 Total fragments: 10740
Proteins after MINT filtering: 49
 Total fragments: 785


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.52

-2.96

0.00
Best peptides

FPRIWPWF

0.00

-3.79

-0.83
         
Interactors      
Q06604

NEEKPLLP

6.10

-6.92

-3.96

FEKGPRMP

6.22

-8.62

-5.66

LLPTRPNK

6.89

-8.01

-5.05
Q12365

IPFIPPQE

5.58

-7.99

-5.03

QIPFIPPQ

8.05

-6.25

-3.29

VPREPLRN

8.50

-9.64

-6.68
P40072

TPSASPML

7.93

-3.66

-0.70

APPTTKPG

8.01

-6.50

-3.54

PPTTKPGT

8.91

-7.89

-4.93
P43603

FTAPTSPS

8.89

-2.87

0.09

APTSPSTS

9.78

-6.24

-3.28

RFTAPTSP

10.08

-7.31

-4.35
P32628

EPPIAPES

6.99

-5.55

-2.59
Q12242

KPCDVPNN

7.51

-3.95

-0.99
P38266

KPPVVPKK

3.29

-7.25

-4.29

LPPPKPFR

4.57

-10.42

-7.46

FPPPPLKP

4.73

-9.97

-7.01
P15891

KEPVKTPS

6.45

-6.41

-3.45

TPEKKPKE

6.85

-7.37

-4.41

KPEVPEDE

7.12

-4.34

-1.38
P53169

VPIMPTLP

6.37

-8.74

-5.78

IMPTLPPR

6.45

-7.04

-4.08

ANSVPIMP

7.01

-7.98

-5.02
P39692

LPPSPKQP

6.05

-8.39

-5.43

KLPPSPKQ

7.07

-6.64

-3.68

PSPKQPVI

8.42

-4.65

-1.69
P17555

RPKKPSTL

6.13

-8.53

-5.57

GPPPRPKK

7.24

-8.16

-5.20

PPPRPKKP

7.37

-9.30

-6.34
Q12344

TTSSPPLP

8.22

-5.21

-2.25

TSPKLPPR

8.48

-5.44

-2.48

PPLPPRQN

9.06

-8.75

-5.79
Q03780

RPPPPPMD

4.80

-9.98

-7.02

PPPPMDMK

6.02

-9.73

-6.77

KRSRPPPP

7.31

-8.00

-5.04
P53316

MPMFPSFG

5.48

-5.74

-2.78

VPYIIPPQ

5.53

-7.37

-4.41

VPPVPYII

5.75

-6.83

-3.87
P32190

RPSTAPAR

6.53

-5.74

-2.78

RRPSTAPA

8.05

-5.81

-2.85

LRRPSTAP

8.29

-4.00

-1.04
P13186

RPPIPAAL

5.21

-9.60

-6.64

IPMSPNYG

6.67

-7.96

-5.00

PEREPPTY

7.16

-6.10

-3.14
P40325

RPSTMPAT

5.35

-6.80

-3.84

RPPPRPQQ

5.92

-8.82

-5.86

RPHQRPST

6.40

-5.57

-2.61
P07278

KTSTPPLP

4.52

-7.21

-4.25

STPPLPMH

7.14

-5.40

-2.44

TPPLPMHF

7.89

-8.69

-5.73
P47129

KPNPPPNR

6.70

-5.60

-2.64

GPPLLPPR

7.61

-6.77

-3.81

LPNRKPNP

7.72

-6.07

-3.11
P47029

LPRDPPSY

6.29

-8.87

-5.91

KHPTPPSL

7.10

-5.85

-2.89

SPITSPMS

7.11

-5.74

-2.78
Q12168

DPYFPQFR

6.11

-6.88

-3.92

IPPPVPNR

6.95

-6.93

-3.97

GPPPLPPR

7.96

-5.70

-2.74
P08458

PKRKPPKL

5.76

-8.51

-5.55

LPKRKPPK

7.84

-8.97

-6.01

NLPKRKPP

8.31

-7.49

-4.53
Q12496

IPKKRPFL

4.69

-8.21

-5.25

IPSNIPKK

5.49

-6.72

-3.76

NIPKKRPF

7.25

-6.59

-3.63
P32793

PTHPSNMS

9.04

-2.37

0.59
P36006

PPPPPPMG

6.27

-10.16

-7.20

IPPPPPPM

6.83

-7.40

-4.44

NIPIPPPP

7.24

-7.61

-4.65
P32790

LPPIKPPR

4.51

-10.31

-7.35

KPPRPTST

7.83

-8.90

-5.94

APAPLDPF

7.95

-5.33

-2.37
Q08412

VPPQLPTR

6.19

-6.06

-3.10

LPPEPLDT

6.96

-7.31

-4.35

WQPLPPEP

7.21

-6.75

-3.79
Q06440

RTPKVEPS

6.13

-7.63

-4.67

DRTPKVEP

10.01

-5.18

-2.22
P38750

LPHNLPHN

7.08

-6.61

-3.65

FPHNAPAS

8.08

-4.75

-1.79

APASSPAY

8.97

-1.97

0.99
P26570

MEPKSPIL

5.39

-5.79

-2.83

DPSTPSKP

6.33

-7.61

-4.65

TPSKPNLE

6.70

-8.23

-5.27
P31374

KPGTPVFP

5.14

-7.27

-4.31

RKTKPPPP

6.72

-9.40

-6.44

KPPPPLDF

6.74

-5.41

-2.45
P38237

IPSKPENT

6.42

-7.55

-4.59

PPPNVPKK

6.67

-7.75

-4.79

PPNVPKKD

6.99

-9.24

-6.28
P34223

SPAEVPKN

7.47

-4.76

-1.80

PDNEPKQG

8.37

-6.41

-3.45

MPDNEPKQ

8.59

-6.42

-3.46
P53118

NPHDLPSH

8.77

-4.39

-1.43

VENPHDLP

8.87

-4.15

-1.19
P53933

RPPPPPIP

5.24

-10.14

-7.18

RRRPPPPP

5.96

-9.01

-6.05

RRPPPPPI

6.61

-7.74

-4.78
P33400

SPQILPPL

7.18

-6.05

-3.09

LPPLPVGI

7.43

-8.38

-5.42

ILPPLPVG

8.12

-6.32

-3.36
Q04439

KPKEPMFE

5.35

-7.23

-4.27

APPPPGMQ

6.66

-7.14

-4.18

KPAPPPPG

6.66

-8.54

-5.58
P33338

RTPTPTPP

6.73

-7.85

-4.89

PTPTPPVV

7.92

-5.17

-2.21

RTPARTPT

8.50

-6.74

-3.78
Q12446

VPPPPPMR

5.35

-7.88

-4.92

FPFPIPEI

5.60

-5.27

-2.31

LPPLPNQF

5.62

-9.71

-6.75
Q04322

TPPTLPPR

6.82

-5.58

-2.62

TPSKSPTS

8.08

-4.47

-1.51

APLDRPQL

8.64

-7.31

-4.35
P39940

DPRLPSSL

8.09

-6.20

-3.24

WDDPRLPS

8.13

-7.15

-4.19

DDPRLPSS

9.13

-6.67

-3.71
P53901

MRPIPPLP

3.67

-9.54

-6.58

QPPLPPIP

6.54

-6.85

-3.89

NDPIILPP

6.64

-6.16

-3.20
P38990

VSSVPNLP

7.52

-7.51

-4.55

NLPKIPNS

7.85

-5.57

-2.61

QPSPIRPV

8.01

-5.60

-2.64
P25693

RPIPTIKP

7.19

-7.08

-4.12
P25333

ITPAPTPT

9.18

-4.93

-1.97

YPEGAPTS

9.37

-7.04

-4.08

TPAPTPTA

10.20

-4.04

-1.08
P25558

SPVKKPMT

5.51

-5.65

-2.69

RHPKSPVK

6.36

-6.49

-3.53

LPNTPRSI

6.39

-6.14

-3.18
P37370

APPIPGMG

4.63

-7.73

-4.77

RPHMPSVR

5.53

-9.84

-6.88

APPIPDIP

5.65

-8.88

-5.92
Q08446

HSPISPLK

6.30

-6.61

-3.65
Q02209

PESKPNVN

8.25

-6.97

-4.01

GPESKPNV

9.62

-4.86

-1.90

 


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