ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-29.PDB
Scoring matrix: RVS167_FYN-SSH-29_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.41
Foldx random average score for Saccharomyces cerevisiae: 10.951

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171208
Proteins after random average filtering: 5078
 Total fragments: 958584
Proteins after disorder filtering: 2835
 Total fragments: 35222
Proteins after pattern filtering: 1460
 Total fragments: 9675
Proteins after MINT filtering: 48
 Total fragments: 679


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

15.41

-2.82

0.00
Best peptides

HYPPIYKFMR

0.00

-11.28

-8.46
         
Interactors      
Q06604

EKPLLPTRPN

6.90

-11.06

-8.24

KNKPKPTPPS

7.98

-7.42

-4.60

PKPTPPSPPA

8.20

-7.47

-4.65
Q12365

DIPGKFPSPL

7.05

-7.28

-4.46

PREPLRNEPT

7.56

-8.93

-6.11

VKDIPGKFPS

8.33

-7.30

-4.48
P40072

NTPSASPMLD

10.61

-8.15

-5.33
P43603

GRFTAPTSPS

10.56

-7.20

-4.38
Q12532

PFKPYINGGD

9.12

-5.61

-2.79
P53901

AMRPIPPLPT

5.66

-10.54

-7.72

SNDPIILPPT

6.54

-7.90

-5.08

NQPPLPPIPT

7.38

-7.93

-5.11
Q12242

TKPCDVPNNG

10.49

-6.20

-3.38
P38266

FLPPPKPFRH

5.31

-11.07

-8.25

IMPPPKPFRH

5.46

-10.56

-7.74

FQPPPKPFRR

5.88

-10.42

-7.60
P15891

AQPPLPSRNV

8.43

-9.66

-6.84

ATPEKKPKEN

8.63

-7.11

-4.29

PRRATPEKKP

8.75

-8.27

-5.45
P53169

IMPTLPPRPY

7.72

-10.59

-7.77

PIMPTLPPRP

9.16

-7.11

-4.29

SVPIMPTLPP

9.22

-9.93

-7.11
P39692

PSPKQPVIMS

8.07

-8.42

-5.60

VMKLPPSPKQ

8.62

-5.74

-2.92

KLPPSPKQPV

9.25

-7.95

-5.13
P17555

GPPPRPKKPS

7.60

-10.05

-7.23

PRPKKPSTLK

8.72

-8.35

-5.53

SKSGPPPRPK

8.88

-6.65

-3.83
Q12344

PKLPPRGKQR

7.69

-8.21

-5.39

SSPPLPPRQN

8.12

-8.62

-5.80

STSPKLPPRG

8.92

-5.53

-2.71
Q03780

IKRSRPPPPP

7.96

-7.25

-4.43

RSRPPPPPMD

8.44

-7.62

-4.80

SRPPPPPMDM

8.88

-9.81

-6.99
P53316

MMPMFPSFGF

5.42

-11.13

-8.31

PMFPSFGFIP

7.28

-9.09

-6.27

PVPYIIPPQN

7.42

-6.82

-4.00
P32190

RRPSTAPARE

9.87

-7.32

-4.50

LRRPSTAPAR

10.85

-5.21

-2.39
P13186

EPLPEREPPT

9.05

-7.11

-4.29

RNSSIPMSPN

9.14

-6.84

-4.02

FKAPSYVPNR

9.21

-6.85

-4.03
P40325

SLPWTYPPRF

5.57

-10.02

-7.20

SQPPRPPRPA

7.08

-9.76

-6.94

SQPRPPPRPQ

8.08

-8.60

-5.78
P07278

KTSTPPLPMH

9.93

-4.53

-1.71
P47129

PLLPPRNTMK

8.37

-8.17

-5.35

SGPPLLPPRN

8.37

-8.41

-5.59

NRKPNPPPNR

8.91

-6.56

-3.74
P47029

GHPASFPKET

7.10

-7.08

-4.26

PLSPITSPMS

7.42

-7.51

-4.69

KHPTPPSLKA

7.52

-8.72

-5.90
Q12168

DDPYFPQFRS

6.64

-10.45

-7.63

QHPVPKPNID

8.22

-5.45

-2.63

DNDDPYFPQF

8.41

-5.16

-2.34
P08458

TNLPKRKPPK

6.91

-7.81

-4.99

NLPKRKPPKL

7.07

-7.27

-4.45

LPKRKPPKLQ

8.34

-7.44

-4.62
Q12496

EIPSNIPKKR

7.41

-7.17

-4.35

SNIPKKRPFL

7.82

-6.42

-3.60

IPSNIPKKRP

9.63

-7.06

-4.24
P32793

HGPTHPSNMS

9.95

-6.79

-3.97

GHGPTHPSNM

10.63

-4.10

-1.28
P36006

ANIPIPPPPP

7.52

-8.61

-5.79

PIPPPPPPMG

7.58

-7.55

-4.73

GQPKDPKFEA

8.19

-10.08

-7.26
P32790

PLDPFKTGGN

8.15

-6.24

-3.42

LPPIKPPRPT

8.17

-9.42

-6.60

IKPPRPTSTT

8.98

-7.96

-5.14
Q08412

KWQPLPPEPL

6.78

-7.65

-4.83

KKKWQPLPPE

7.21

-6.91

-4.09

ELPTQPVRKN

7.34

-9.25

-6.43
Q06440

KKDRTPKVEP

9.84

-7.62

-4.80

KDRTPKVEPS

10.49

-4.81

-1.99
P38750

SPPGVFPVRG

7.98

-8.39

-5.57

PHLGLPHNLP

8.46

-7.54

-4.72

GLPHNLPHNH

8.64

-8.63

-5.81
P26570

PKSPILKTNN

8.84

-6.27

-3.45

PDPSTPSKPN

9.29

-7.54

-4.72

STPSKPNLEV

9.71

-7.67

-4.85
P31374

KKPGTPVFPN

6.28

-11.16

-8.34

ISPERPSFRQ

7.21

-12.51

-9.69

FRKTKPPPPL

7.54

-7.24

-4.42
P38237

LNDPFVPPPN

7.43

-5.52

-2.70

ENFQIPSKPE

7.53

-9.29

-6.47

DLNDPFVPPP

9.08

-4.84

-2.02
P34223

PMPDNEPKQG

9.16

-6.59

-3.77

EQPMPDNEPK

9.19

-4.30

-1.48

SSPAEVPKNE

10.38

-6.21

-3.39
P53118

ENPHDLPSHL

9.75

-7.22

-4.40

PHDLPSHLGS

10.04

-6.92

-4.10
P53933

RRPPPPPIPS

8.09

-9.14

-6.32

GYNDLPMELP

8.18

-8.69

-5.87

TRRRPPPPPI

8.68

-6.97

-4.15
P33400

ILPPLPVGIS

7.75

-8.41

-5.59

TSPQILPPLP

7.91

-7.40

-4.58

STSPQILPPL

9.23

-5.23

-2.41
Q04439

SKPKEPMFEA

7.66

-9.82

-7.00

SKKPAPPPPG

7.71

-7.44

-4.62

RHSKKPAPPP

8.14

-5.71

-2.89
P33338

PTPPVVAEPA

8.69

-6.73

-3.91

SWSGPLTPPT

9.27

-4.86

-2.04

VTPARTPART

10.38

-5.51

-2.69
Q12446

RLPAPPPPPR

7.30

-7.36

-4.54

PFPFPIPEIP

7.63

-6.52

-3.70

SNPFPFPIPE

7.78

-7.89

-5.07
Q04322

STPPTLPPRR

7.54

-8.92

-6.10

TPPTLPPRRI

8.40

-10.02

-7.20

TSPPLPPRAD

8.69

-8.94

-6.12
P39940

TWDDPRLPSS

8.92

-6.62

-3.80

TTWDDPRLPS

9.85

-7.10

-4.28

DDPRLPSSLD

10.20

-6.68

-3.86
P38990

NQPSPIRPVL

9.46

-5.41

-2.59

QPSPIRPVLP

9.56

-7.70

-4.88

SVSSVPNLPS

9.64

-6.45

-3.63
P25693

ENRPIPTIKP

8.17

-8.25

-5.43
P25333

DKYPEGAPTS

10.90

-5.37

-2.55
P25558

PKSPVKKPMT

6.77

-7.03

-4.21

RHPKSPVKKP

7.64

-8.43

-5.61

KSPVKKPMTS

8.65

-8.04

-5.22
P37370

QMPKPRPFQN

7.08

-10.40

-7.58

SQMPKPRPFQ

7.64

-7.92

-5.10

KSPSQPPLPS

7.80

-9.06

-6.24
Q02209

IYKGPESKPN

8.40

-7.45

-4.63

 


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