ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-16.PDB
Scoring matrix: RVS167_FYN-SSH-16_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.22
Foldx random average score for Saccharomyces cerevisiae: 16.419

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176286
Proteins after random average filtering: 5078
 Total fragments: 920899
Proteins after disorder filtering: 3185
 Total fragments: 62186
Proteins after pattern filtering: 1553
 Total fragments: 9318
Proteins after MINT filtering: 49
 Total fragments: 585


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.22

-1.39

0.00
Best peptides

FHPIRPIWF

0.00

3.67

5.06
         
Interactors      
Q06604

LLPTRPNKA

8.20

-5.00

-3.61

GPRMPSRGR

12.28

-6.73

-5.34

TPPSPPAKR

12.43

-4.82

-3.43
Q12365

IPFIPPQED

11.40

-5.31

-3.92

VKDIPGKFP

13.31

-5.08

-3.69

IVPREPLRN

13.73

-5.04

-3.65
P40072

PPTTKPGTN

12.77

-6.56

-5.17

TPSASPMLD

14.20

-5.25

-3.86

APPTTKPGT

16.01

-2.98

-1.59
P43603

APTSPSTSS

14.71

-3.92

-2.53

TAPTSPSTS

14.81

-3.54

-2.15

GRFTAPTSP

15.33

-2.50

-1.11
P32628

EPPIAPESA

11.14

-7.20

-5.81
Q12242

KPCDVPNNG

13.11

-5.21

-3.82

TKPCDVPNN

16.24

-3.91

-2.52
P38266

KPPVVPKKK

9.98

-6.90

-5.51

TPPRPPPSR

10.52

-7.18

-5.79

LKKKPPVVP

11.42

-5.24

-3.85
P15891

TPEKKPKEN

11.81

-6.03

-4.64

EPVKTPSPA

13.84

-4.93

-3.54

APPPPPRRA

13.87

-5.88

-4.49
P53169

MPTLPPRPY

11.89

-7.00

-5.61

IMPTLPPRP

12.73

-5.09

-3.70

TANSVPIMP

14.16

-3.70

-2.31
P39692

PSPKQPVIM

13.25

-4.96

-3.57

SPKQPVIMS

13.94

-5.32

-3.93

KLPPSPKQP

14.70

-5.18

-3.79
P17555

RPKKPSTLK

9.67

-6.48

-5.09

GPPPRPKKP

12.88

-6.62

-5.23

PPPRPKKPS

15.15

-4.89

-3.50
Q12344

SPKLPPRGK

12.99

-6.21

-4.82

SPPLPPRQN

13.14

-6.84

-5.45

PLPPRQNVA

14.74

-3.82

-2.43
Q03780

IPPRSPNRN

10.48

-6.64

-5.25

APDIPPRSP

10.89

-6.98

-5.59

RPPPPPMDM

11.68

-7.05

-5.66
P53316

VPYIIPPQN

10.98

-7.06

-5.67

MPMFPSFGF

11.22

-6.28

-4.89

IPQVPPVPY

11.34

-6.34

-4.95
P32190

RPSTAPARE

10.95

-4.72

-3.33

GLRRPSTAP

14.91

-5.14

-3.75

RRPSTAPAR

15.27

-4.61

-3.22
P13186

LPEREPPTY

9.66

-8.27

-6.88

RPPIPAALP

11.79

-8.83

-7.44

RNSSIPMSP

13.42

-4.74

-3.35
P40325

RPHQRPSTM

8.49

-7.93

-6.54

LPWTYPPRF

9.21

-8.48

-7.09

RPPPRPQQN

10.32

-6.50

-5.11
P07278

KTSTPPLPM

15.78

-3.16

-1.77
P47129

RKPNPPPNR

9.84

-5.82

-4.43

TLPNRKPNP

11.56

-4.78

-3.39

LPNRKPNPP

11.66

-7.20

-5.81
P47029

KHPTPPSLK

8.44

-1.97

-0.58

LPRDPPSYK

10.07

-5.97

-4.58

ILPRDPPSY

10.81

-6.32

-4.93
Q12168

HPVPKPNID

13.10

-4.97

-3.58

PPPLPPRAN

13.72

-6.15

-4.76

PVPNRPGGT

13.80

-2.51

-1.12
P08458

NLPKRKPPK

11.39

-5.22

-3.83

PKRKPPKLQ

12.99

-5.84

-4.45

TPITNPSSS

13.27

-4.99

-3.60
Q12496

IPSNIPKKR

10.55

-6.03

-4.64

PSNIPKKRP

15.46

-6.10

-4.71

EIPSNIPKK

16.11

-1.69

-0.30
P32793

HGPTHPSNM

12.29

-5.31

-3.92

GPTHPSNMS

13.55

-4.83

-3.44

SLGHGPTHP

15.51

-4.01

-2.62
P36006

KPKNPGGLS

12.66

-5.02

-3.63

KSNKKPKNP

13.21

-6.15

-4.76

NIPIPPPPP

14.09

-3.72

-2.33
P32790

LPPIKPPRP

9.26

-9.23

-7.84

PPIKPPRPT

14.20

-4.54

-3.15

KPPRPTSTT

14.66

-5.05

-3.66
Q08412

ELPTQPVRK

11.22

-3.87

-2.48

LPTQPVRKN

12.98

-6.57

-5.18

GKNSRPQQP

13.64

-4.68

-3.29
Q06440

KDRTPKVEP

14.07

-4.42

-3.03

RTPKVEPSK

14.62

-5.33

-3.94
P38750

LPHNLPHNH

9.22

-5.94

-4.55

FPHNAPASS

10.76

-5.43

-4.04

PPGVFPVRG

12.96

-5.45

-4.06
P26570

MEPKSPILK

9.49

-3.25

-1.86

DPTDSPNEW

12.37

-4.23

-2.84

TPLNSPGLS

13.13

-4.17

-2.78
P31374

ISPERPSFR

11.95

-2.50

-1.11

TPDDLPPLK

12.16

-5.64

-4.25

SPERPSFRQ

12.29

-5.56

-4.17
P38237

PPPNVPKKD

12.41

-5.44

-4.05

DPFVPPPNV

13.62

-5.23

-3.84

IPSKPENTV

13.73

-5.24

-3.85
P34223

MPDNEPKQG

11.83

-5.85

-4.46

LEVTDPSDP

13.92

-3.42

-2.03

SPAEVPKNE

14.35

-3.72

-2.33
P53118

PHDLPSHLG

14.01

-2.17

-0.78

ENPHDLPSH

16.00

-2.60

-1.21
P53933

PPPIPSTQK

10.79

-6.65

-5.26

RTRRRPPPP

12.96

-7.52

-6.13

RPPPPPIPS

13.21

-4.78

-3.39
P33400

QPPNAPSYQ

11.24

-5.00

-3.61

SPQILPPLP

12.18

-6.81

-5.42

HSTSPQILP

14.52

-5.34

-3.95
Q04439

RHSKKPAPP

10.14

-5.27

-3.88

SKPKEPMFE

12.55

-2.74

-1.35

NIPTPPQNR

13.00

-2.91

-1.52
P33338

TPARTPART

14.43

-4.61

-3.22

LSWSGPLTP

15.15

-4.04

-2.65

PTPTPPVVA

15.64

-2.08

-0.69
Q12446

PPPRRGPAP

11.27

-6.97

-5.58

LPPASPEVR

12.04

-5.48

-4.09

IPEIPSTQS

12.12

-6.10

-4.71
Q04322

TPPTLPPRR

11.09

-6.47

-5.08

TPSKSPTSA

12.05

-6.24

-4.85

SPPLPPRAD

14.44

-5.63

-4.24
P39940

WDDPRLPSS

14.47

-2.35

-0.96

DPRLPSSLD

15.86

-5.02

-3.63
P53901

DPIILPPTF

10.02

-7.47

-6.08

HNYNQPPLP

12.09

-6.12

-4.73

LPPIPTRDD

12.37

-6.66

-5.27
P38990

PSPIRPVLP

11.06

-5.88

-4.49

RNQNLPKIP

12.35

-4.59

-3.20

LPSAPSSTR

12.39

-5.95

-4.56
P25693

NRPIPTIKP

13.77

-6.39

-5.00
P25333

YPEGAPTSG

15.13

-4.70

-3.31

TAITPAPTP

16.20

-4.60

-3.21
P25558

RHPKSPVKK

6.04

-4.45

-3.06

SPVKKPMTS

11.57

-5.70

-4.31

LPNTPRSIN

12.77

-6.76

-5.37
P37370

VPQNRPHMP

8.11

-6.50

-5.11

RPHMPSVRP

10.38

-8.65

-7.26

MPKPRPFQN

10.70

-6.49

-5.10
Q08446

SHSPISPLK

13.86

-0.01

1.38

NSSHSPISP

14.55

-3.73

-2.34
Q02209

PESKPNVNF

13.28

-3.41

-2.02

GPESKPNVN

13.51

-3.56

-2.17

 


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