ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-15.PDB
Scoring matrix: RVS167_FYN-SSH-15_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.18
Foldx random average score for Saccharomyces cerevisiae: 12.036

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176286
Proteins after random average filtering: 5078
 Total fragments: 983563
Proteins after disorder filtering: 3065
 Total fragments: 39118
Proteins after pattern filtering: 1445
 Total fragments: 6867
Proteins after MINT filtering: 47
 Total fragments: 459


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

14.18

-1.42

0.00
Best peptides

YDWIKPKRV

0.00

-7.07

-5.65
         
Interactors      
Q06604

PPPLPTRRD

7.43

-4.99

-3.57

SPPPLPTRR

7.56

-6.06

-4.64

EKPLLPTRP

8.41

-3.41

-1.99
Q12365

IVPREPLRN

8.77

-5.57

-4.15

IPFIPPQED

9.94

-4.69

-3.27

QIPFIPPQE

10.53

-3.90

-2.48
P40072

APPTTKPGT

10.53

-6.22

-4.80

PPTTKPGTN

10.87

-4.89

-3.47

TPSASPMLD

11.47

-3.35

-1.93
P43603

RFTAPTSPS

11.27

-3.75

-2.33

FTAPTSPST

11.95

-1.76

-0.34
P32628

EPPIAPESA

9.32

-5.51

-4.09

PPIAPESAT

11.92

-4.58

-3.16
Q12242

KPCDVPNNG

10.85

-4.31

-2.89
P38266

MPPPKPFRH

5.59

-5.65

-4.23

LPPPKPFRH

6.11

-5.75

-4.33

QPPPKPFRR

6.40

-7.11

-5.69
P15891

APPPPPRRA

7.60

-5.69

-4.27

QPPLPSRNV

8.32

-6.11

-4.69

TPSKSPAPV

8.77

-4.61

-3.19
P53169

MPTLPPRPY

7.22

-7.04

-5.62

IMPTLPPRP

8.58

-4.28

-2.86

ANSVPIMPT

11.10

-5.07

-3.65
P39692

LPPSPKQPV

9.45

-6.77

-5.35

PSPKQPVIM

11.57

-5.36

-3.94
P17555

PPPAPPASV

9.55

-6.05

-4.63

RPKKPSTLK

10.18

-6.27

-4.85

PRPKKPSTL

10.20

-5.70

-4.28
Q12344

TSPKLPPRG

8.74

-3.68

-2.26

SPPLPPRQN

11.09

-5.01

-3.59

SSPPLPPRQ

11.63

-3.46

-2.04
Q03780

IPPRSPNRN

7.99

-7.59

-6.17

RPPPPPMDM

9.65

-8.02

-6.60

SAPDIPPRS

10.16

-2.43

-1.01
P53316

IPQVPPVPY

8.58

-6.83

-5.41

MPMFPSFGF

8.99

-6.72

-5.30

VPYIIPPQN

9.31

-5.10

-3.68
P32190

RPSTAPARE

6.04

-6.48

-5.06

RRPSTAPAR

10.00

-5.28

-3.86

LRRPSTAPA

11.08

-3.21

-1.79
P13186

APSYVPNRV

4.45

-4.93

-3.51

LPEREPPTY

8.64

-8.19

-6.77

RPPIPAALP

8.84

-6.33

-4.91
P40325

LPWTYPPRF

5.47

-5.16

-3.74

YVQPGDPRL

8.45

-6.42

-5.00

RPSTMPATS

8.71

-6.13

-4.71
P07278

KTSTPPLPM

11.80

-5.66

-4.24
P47129

GPPLLPPRN

7.34

-5.11

-3.69

KPNPPPNRS

8.11

-6.13

-4.71

RKPNPPPNR

8.94

-5.93

-4.51
P47029

YDGHPASFP

10.48

-6.25

-4.83

KLPNLPNDA

10.52

-3.41

-1.99

ILPRDPPSY

10.54

-5.70

-4.28
Q12168

GPPPLPPRA

7.86

-4.55

-3.13

IPPPVPNRP

8.74

-5.37

-3.95

DDPYFPQFR

9.16

-5.12

-3.70
P08458

LPKRKPPKL

9.26

-11.34

-9.92

TPITNPSSS

11.32

-4.10

-2.68

NLPKRKPPK

11.97

-6.56

-5.14
Q12496

IPSNIPKKR

9.30

-5.88

-4.46

PSNIPKKRP

9.92

-5.42

-4.00

NIPKKRPFL

10.70

-7.70

-6.28
P36006

NIPIPPPPP

10.25

-5.15

-3.73

KKPKNPGGL

10.41

-6.05

-4.63

KPKNPGGLS

11.58

-4.34

-2.92
P32790

LPPIKPPRP

5.19

-6.96

-5.54

PPPAMPARP

8.96

-5.57

-4.15

KPPRPTSTT

10.13

-8.95

-7.53
Q08412

VPPQLPTRT

6.64

-4.89

-3.47

ELPTQPVRK

9.31

-5.62

-4.20

DIELPTQPV

10.54

-4.98

-3.56
Q06440

KDRTPKVEP

11.07

-5.97

-4.55

RTPKVEPSK

11.55

-4.41

-2.99
P38750

PPGVFPVRG

6.46

-6.24

-4.82

LPHNLPHNH

9.98

-4.91

-3.49

FPHNAPASS

10.27

-4.61

-3.19
P26570

MEPKSPILK

10.38

-5.86

-4.44

EPKSPILKT

11.40

-5.52

-4.10

TPLNSPGLS

11.57

-3.57

-2.15
P31374

RKTKPPPPL

9.34

-6.96

-5.54

GNNISPERP

9.40

-7.52

-6.10

FPNLDPTHS

9.60

-5.81

-4.39
P38237

DPFVPPPNV

7.87

-6.09

-4.67

IPSKPENTV

8.89

-4.78

-3.36

NDPFVPPPN

9.08

-4.33

-2.91
P34223

MPDNEPKQG

10.13

-4.12

-2.70

SPAEVPKNE

11.38

-2.95

-1.53
P53118

NPHDLPSHL

10.52

-5.62

-4.20
P53933

APPPLPNRQ

9.49

-5.88

-4.46

RPPPPPIPS

10.09

-5.89

-4.47

RRPPPPPIP

10.29

-5.02

-3.60
P33400

PQILPPLPV

9.62

-5.56

-4.14

LPPLPVGIS

9.88

-5.00

-3.58

SPQILPPLP

11.08

-6.64

-5.22
Q04439

NIPTPPQNR

9.39

-5.69

-4.27

RPSPPTAAT

9.92

-5.29

-3.87

IPTPPQNRD

10.31

-5.82

-4.40
P33338

TPARTPART

7.31

-7.11

-5.69

TPTPTPPVV

9.26

-4.27

-2.85

RTPTPTPPV

9.39

-4.83

-3.41
Q12446

VPPPPPMRT

7.58

-5.82

-4.40

APPPPPHRH

8.12

-5.64

-4.22

APPPPPRRG

8.23

-6.15

-4.73
Q04322

TPPTLPPRR

6.15

-6.71

-5.29

PPTLPPRRI

7.23

-9.53

-8.11

TSPPLPPRA

9.26

-3.52

-2.10
P39940

DDPRLPSSL

11.11

-7.24

-5.82

DPRLPSSLD

11.39

-3.63

-2.21
P53901

MRPIPPLPT

7.77

-7.02

-5.60

PLPPIPTRD

8.61

-5.21

-3.79

NDPIILPPT

8.75

-6.79

-5.37
P38990

NQPSPIRPV

9.90

-4.55

-3.13

LPSAPSSTR

10.49

-5.91

-4.49

PSAPSSTRL

10.84

-3.95

-2.53
P25693

NRPIPTIKP

9.95

-6.15

-4.73
P25333

YPEGAPTSG

10.54

-5.63

-4.21

KYPEGAPTS

11.70

-2.88

-1.46
P25558

KSPVKKPMT

9.35

-5.51

-4.09

RHPKSPVKK

9.90

-6.16

-4.74

EELPNTPRS

10.60

-2.90

-1.48
P37370

RPHMPSVRP

7.55

-7.08

-5.66

LPPPPPPSV

8.36

-6.77

-5.35

APPIPTSHA

9.28

-6.27

-4.85
Q02209

KGPESKPNV

10.72

-4.27

-2.85

YKGPESKPN

11.05

-4.11

-2.69

GPESKPNVN

11.83

-3.18

-1.76

 


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