ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-12.PDB
Scoring matrix: RVS167_FYN-SSH-12_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.68
Foldx random average score for Saccharomyces cerevisiae: 11.545

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181364
Proteins after random average filtering: 5078
 Total fragments: 803729
Proteins after disorder filtering: 3141
 Total fragments: 60671
Proteins after pattern filtering: 1583
 Total fragments: 11456
Proteins after MINT filtering: 49
 Total fragments: 824


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.68

-1.38

0.00
Best peptides

RKFRRWRR

0.00

-5.32

-3.94
         
Interactors      
Q06604

PSPPAKRI

6.66

-4.97

-3.59

KGPRMPSR

7.11

-4.70

-3.32

PTPPSPPA

8.36

-3.41

-2.03
Q12365

IVPREPLR

6.66

-3.93

-2.55

DIPGKFPS

8.47

-3.97

-2.59

QIPFIPPQ

9.61

-2.61

-1.23
P40072

APPTTKPG

9.95

-3.89

-2.51

PTTKPGTN

10.37

-1.36

0.02

NTPSASPM

10.60

-1.87

-0.49
P43603

TAPTSPST

10.09

-2.11

-0.73

FTAPTSPS

10.88

-1.73

-0.35
Q12532

PFKPYING

10.68

-4.03

-2.65
P32628

PIAPESAT

11.00

-1.72

-0.34

EPPIAPES

11.18

-1.90

-0.52
Q12242

TKPCDVPN

9.78

-2.06

-0.68
P38266

PPPKPFRR

6.08

-5.14

-3.76

PPPKPFRH

6.46

-5.70

-4.32

IMPPPKPF

7.02

-3.80

-2.42
P15891

APPPPPRR

7.64

-4.26

-2.88

AAPPPPPR

7.84

-3.59

-2.21

RATPEKKP

7.88

-3.67

-2.29
P53169

IMPTLPPR

8.82

-2.47

-1.09

MPTLPPRP

9.70

-4.05

-2.67

PIMPTLPP

9.80

-5.85

-4.47
P39692

KLPPSPKQ

8.71

-3.93

-2.55

PSPKQPVI

8.94

-2.53

-1.15

PKQPVIMS

9.34

-2.74

-1.36
P17555

PPPRPKKP

6.64

-6.12

-4.74

PRPKKPST

7.99

-2.75

-1.37

PAPPPPPP

8.28

-3.50

-2.12
Q12344

TSPKLPPR

7.71

-3.22

-1.84

SSPPLPPR

7.92

-3.35

-1.97

SPPLPPRQ

9.19

-4.35

-2.97
Q03780

KRSRPPPP

6.44

-2.99

-1.61

SRPPPPPM

7.31

-3.56

-2.18

RSRPPPPP

7.47

-3.56

-2.18
P53316

WMMPMFPS

6.56

-7.06

-5.68

PMFPSFGF

6.83

-4.56

-3.18

QVPPVPYI

8.37

-3.32

-1.94
P32190

RRPSTAPA

9.68

-2.27

-0.89

PSTAPARE

9.91

-1.24

0.14

LRRPSTAP

10.05

-2.74

-1.36
P13186

FKAPSYVP

7.98

-2.80

-1.42

PSYVPNRV

8.67

-4.43

-3.05

SIPMSPNY

8.98

-3.57

-2.19
P40325

SQPRPPPR

6.07

-5.15

-3.77

QPPRPPRP

6.24

-7.34

-5.96

SQPPRPPR

7.74

-3.63

-2.25
P07278

STPPLPMH

8.79

-3.73

-2.35

TSTPPLPM

10.21

-2.57

-1.19

KTSTPPLP

10.53

-0.23

1.15
P47129

RKPNPPPN

8.13

-3.41

-2.03

PNPPPNRS

8.49

-4.55

-3.17

TLPNRKPN

8.61

-4.28

-2.90
P47029

ILPRDPPS

6.65

-4.51

-3.13

GHPASFPK

8.19

-4.41

-3.03

SKHPTPPS

8.77

-2.21

-0.83
Q12168

PYFPQFRS

5.74

-4.82

-3.44

QHPVPKPN

8.27

-3.57

-2.19

GPPPLPPR

9.02

-3.32

-1.94
P08458

NLPKRKPP

6.89

-4.01

-2.63

PKRKPPKL

7.48

-3.27

-1.89

LPKRKPPK

9.07

-5.05

-3.67
Q12496

EIPSNIPK

9.18

-2.58

-1.20

SNIPKKRP

9.34

-3.45

-2.07

PSNIPKKR

9.39

-2.68

-1.30
P32793

HGPTHPSN

10.06

-2.25

-0.87

PTHPSNMS

10.34

-2.47

-1.09

GHGPTHPS

11.16

-2.17

-0.79
P36006

PIPPPPPP

8.03

-3.66

-2.28

KKPKNPGG

8.42

-2.83

-1.45

GQPKDPKF

8.57

-2.68

-1.30
P32790

IKPPRPTS

7.79

-3.55

-2.17

LPPIKPPR

9.63

-2.67

-1.29

EGPPPAMP

9.63

-2.96

-1.58
Q08412

PLPPEPLD

9.15

-3.16

-1.78

KWQPLPPE

9.53

-2.33

-0.95

ELPTQPVR

9.71

-2.41

-1.03
Q06440

RTPKVEPS

9.76

-2.04

-0.66

DRTPKVEP

10.55

-0.77

0.61
P38750

DTFPHNAP

8.75

-3.86

-2.48

RSPPGVFP

9.82

-3.23

-1.85

SPPGVFPV

9.86

-3.72

-2.34
P26570

PSTPSKPN

8.10

-3.28

-1.90

MEPKSPIL

8.53

-3.32

-1.94

YSTPLNSP

10.23

-1.83

-0.45
P31374

PERPSFRQ

5.83

-6.04

-4.66

RKTKPPPP

7.04

-2.67

-1.29

EQPRLPST

7.51

-4.32

-2.94
P38237

DPFVPPPN

9.17

-3.45

-2.07

FVPPPNVP

9.35

-2.83

-1.45

FQIPSKPE

10.12

-3.92

-2.54
P34223

QPMPDNEP

10.35

-3.60

-2.22

SSPAEVPK

10.67

-2.38

-1.00

TDPSDPNS

10.82

-2.20

-0.82
P53933

TRRRPPPP

5.52

-5.63

-4.25

RRPPPPPI

6.74

-3.73

-2.35

RRRPPPPP

6.75

-3.53

-2.15
P33400

ILPPLPVG

9.27

-3.22

-1.84

PNAPSYQS

9.59

-2.37

-0.99

STSPQILP

9.61

-2.68

-1.30
Q04439

SKPKEPMF

7.66

-2.48

-1.10

NIPPPPPP

7.97

-3.57

-2.19

KKPAPPPP

8.38

-2.92

-1.54
P33338

ARTPTPTP

9.13

-2.01

-0.63

TPARTPAR

9.32

-3.98

-2.60

PARTPART

9.39

-1.49

-0.11
Q12446

APPPPPRR

7.64

-4.26

-2.88

PPPPPHRH

7.78

-6.14

-4.76

PAPPPPPR

7.89

-3.46

-2.08
Q04322

TSPPLPPR

7.92

-3.32

-1.94

NATPSKSP

8.78

-2.98

-1.60

SPPLPPRA

9.22

-5.35

-3.97
P39940

DDPRLPSS

7.73

-4.45

-3.07

PSSSPHSQ

10.65

-1.35

0.03
P53901

MAMRPIPP

5.45

-5.84

-4.46

NSPKLPPL

8.17

-3.45

-2.07

MRPIPPLP

8.58

-3.61

-2.23
P38990

NQPSPIRP

8.07

-3.75

-2.37

PSPIRPVL

9.27

-2.33

-0.95

NLPKIPNS

9.31

-2.83

-1.45
P25693

RPIPTIKP

11.36

-2.75

-1.37
P25333

DKYPEGAP

9.18

-2.31

-0.93

AITPAPTP

9.60

-1.90

-0.52

ITPAPTPT

11.15

-2.31

-0.93
P25558

KSPVKKPM

8.18

-4.06

-2.68

RHPKSPVK

8.19

-2.66

-1.28

PKSPVKKP

8.41

-2.60

-1.22
P37370

PKPRPFQN

4.87

-5.67

-4.29

SQMPKPRP

7.07

-6.81

-5.43

EKPPSPPV

7.52

-3.41

-2.03
Q08446

HSPISPLK

9.36

-3.61

-2.23

SSHSPISP

9.97

-2.51

-1.13

SHSPISPL

10.82

-0.86

0.52
Q02209

KGPESKPN

9.34

-2.98

-1.60

PESKPNVN

10.09

-0.75

0.63

YKGPESKP

10.78

-0.81

0.57

 


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