ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-11.PDB
Scoring matrix: RVS167_FYN-SSH-11_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.09
Foldx random average score for Saccharomyces cerevisiae: 8.731

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2186442
Proteins after random average filtering: 5078
 Total fragments: 1088292
Proteins after disorder filtering: 3374
 Total fragments: 79027
Proteins after pattern filtering: 1605
 Total fragments: 11202
Proteins after MINT filtering: 49
 Total fragments: 832


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.09

-2.04

0.00
Best peptides

YDPIIRK

0.00

-5.39

-3.35
         
Interactors      
Q06604

KPKPTPP

4.74

-4.62

-2.58

SPPPLPT

5.84

-5.51

-3.47

KPTPPSP

5.86

-6.29

-4.25
Q12365

QIPFIPP

5.27

-5.52

-3.48

IPFIPPQ

5.42

-4.92

-2.88

PREPLRN

6.32

-6.94

-4.90
P40072

APPTTKP

5.59

-4.63

-2.59

PPTTKPG

6.83

-5.46

-3.42

TPSASPM

7.46

-3.71

-1.67
P43603

FTAPTSP

5.65

-3.47

-1.43

APTSPST

8.14

-4.87

-2.83

TAPTSPS

8.25

-1.03

1.01
P32628

EPPIAPE

8.07

-5.01

-2.97
Q12242

KPCDVPN

7.48

-5.28

-3.24
P38266

KPPVVPK

3.46

-8.01

-5.97

FPPPPLK

3.96

-7.07

-5.03

VPPVVPK

4.38

-7.09

-5.05
P15891

TPEKKPK

4.85

-4.60

-2.56

PPPPRRA

5.30

-7.79

-5.75

FTPSKSP

5.88

-4.65

-2.61
P53169

IMPTLPP

4.58

-4.45

-2.41

NSVPIMP

6.12

-3.03

-0.99

TLPPRPY

6.63

-5.88

-3.84
P39692

KLPPSPK

5.24

-4.70

-2.66

SPKQPVI

6.89

-5.54

-3.50

LPPSPKQ

7.00

-5.38

-3.34
P17555

GPPPRPK

5.01

-6.07

-4.03

PRPKKPS

5.62

-5.63

-3.59

RPKKPST

5.92

-5.91

-3.87
Q12344

TSPKLPP

5.87

-3.65

-1.61

SSPPLPP

6.45

-3.75

-1.71

PPLPPRQ

6.74

-6.64

-4.60
Q03780

RPPPPPM

5.59

-8.18

-6.14

PPPPMDM

6.18

-7.53

-5.49

APDIPPR

6.21

-7.66

-5.62
P53316

VPYIIPP

3.83

-5.78

-3.74

FIPQVPP

4.59

-5.55

-3.51

IPPQNPA

5.17

-4.20

-2.16
P32190

RRPSTAP

5.71

-4.68

-2.64

RPSTAPA

8.33

-6.91

-4.87
P13186

YVPNRVP

3.77

-6.69

-4.65

IPAALPP

4.85

-5.13

-3.09

RPPIPAA

5.59

-7.22

-5.18
P40325

RPPPRPQ

4.42

-7.85

-5.81

RPHQRPS

5.28

-5.67

-3.63

PRPPRPA

5.46

-5.64

-3.60
P07278

PPLPMHF

6.90

-8.33

-6.29

STPPLPM

7.16

-4.40

-2.36

TSTPPLP

8.71

-3.01

-0.97
P47129

NRKPNPP

5.48

-2.35

-0.31

GPPLLPP

6.10

-6.03

-3.99

TLPNRKP

6.38

-3.26

-1.22
P47029

LSPITSP

5.82

-2.49

-0.45

KLPNLPN

6.38

-4.54

-2.50

PLSPITS

6.56

-5.63

-3.59
Q12168

GPPPLPP

5.51

-5.74

-3.70

PPVPNRP

5.66

-5.12

-3.08

IPPPVPN

6.13

-5.71

-3.67
P08458

NLPKRKP

5.20

-4.69

-2.65

LPKRKPP

6.11

-8.63

-6.59

VTPITNP

6.63

-1.19

0.85
Q12496

IPSNIPK

3.50

-5.75

-3.71

IPKKRPF

4.85

-8.49

-6.45

NIPKKRP

5.77

-5.92

-3.88
P32793

GHGPTHP

8.30

-1.04

1.00
P36006

IPPPPPP

5.33

-4.75

-2.71

IPIPPPP

5.73

-5.46

-3.42

PPPPMGQ

5.88

-6.79

-4.75
P32790

LPPIKPP

4.53

-5.87

-3.83

APAPLDP

5.75

-4.59

-2.55

IKPPRPT

6.11

-4.95

-2.91
Q08412

VPPQLPT

5.34

-5.40

-3.36

PPEPLDT

6.00

-5.68

-3.64

KWQPLPP

6.27

-4.19

-2.15
Q06440

RTPKVEP

7.23

-4.20

-2.16

PKVEPSK

7.46

-5.24

-3.20
P38750

SPPGVFP

7.24

-4.91

-2.87

FPHNAPA

7.35

-4.85

-2.81

GLPHNLP

7.38

-3.07

-1.03
P26570

PKSPILK

5.86

-5.10

-3.06

MEPKSPI

6.34

-4.27

-2.23

PDPSTPS

6.63

-2.87

-0.83
P31374

ISPERPS

5.87

-1.92

0.12

FEQPRLP

6.00

-5.80

-3.76

PPPPLDF

6.11

-8.52

-6.48
P38237

NDPFVPP

4.77

-3.72

-1.68

PPPNVPK

4.98

-6.34

-4.30

VPPPNVP

5.62

-4.21

-2.17
P34223

SPAEVPK

5.58

-4.79

-2.75

PDNEPKQ

7.00

-4.91

-2.87

MPDNEPK

7.43

-3.79

-1.75
P53118

NPHDLPS

6.65

-4.29

-2.25
P53933

RPPPPPI

4.81

-7.29

-5.25

PPPPIPS

4.83

-6.42

-4.38

RRPPPPP

5.34

-5.80

-3.76
P33400

ILPPLPV

4.85

-4.34

-2.30

SPQILPP

5.33

-5.01

-2.97

PPLPVGI

5.46

-5.55

-3.51
Q04439

IPPPPPP

5.33

-4.75

-2.71

PPPPSSK

5.52

-5.97

-3.93

KPAPPPP

5.52

-5.15

-3.11
P33338

WSGPLTP

5.84

-2.50

-0.46

TPTPTPP

6.42

-3.09

-1.05

RTPARTP

6.60

-5.60

-3.56
Q12446

FPFPIPE

3.39

-6.58

-4.54

FPFPVPQ

4.21

-6.30

-4.26

IPPTLPS

4.71

-5.12

-3.08
Q04322

TPPTLPP

5.17

-4.87

-2.83

TSPPLPP

6.32

-3.79

-1.75

APLDRPQ

6.62

-4.94

-2.90
P39940

WDDPRLP

4.37

-4.99

-2.95

DDPRLPS

6.49

-5.41

-3.37

DPRLPSS

8.48

-4.47

-2.43
P53901

NDPIILP

3.64

-4.30

-2.26

DPIILPP

5.08

-4.91

-2.87

AMRPIPP

5.16

-4.74

-2.70
P38990

QPSPIRP

4.81

-7.22

-5.18

PSPIRPV

5.34

-3.62

-1.58

NLPKIPN

5.96

-4.94

-2.90
P25693

PIPTIKP

5.46

-5.92

-3.88
P25333

TPAPTPT

6.76

-2.49

-0.45

YPEGAPT

7.16

-5.62

-3.58

ITPAPTP

7.83

-3.70

-1.66
P25558

KSPVKKP

5.43

-4.15

-2.11

RHPKSPV

6.17

-4.19

-2.15

SPVKKPM

6.22

-5.86

-3.82
P37370

RPSPISP

3.97

-6.45

-4.41

AAPPIPI

4.91

-4.69

-2.65

PPIPIVP

5.01

-6.22

-4.18
Q08446

SHSPISP

6.60

-3.19

-1.15

SPISPLK

7.42

-5.18

-3.14

HSPISPL

8.48

-3.64

-1.60
Q02209

KGPESKP

7.79

-2.27

-0.23

PESKPNV

8.34

-3.90

-1.86

GPESKPN

8.49

-4.72

-2.68

 


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