ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-10.PDB
Scoring matrix: RVS167_FYN-SSH-10_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.06
Foldx random average score for Saccharomyces cerevisiae: 16.891

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181364
Proteins after random average filtering: 5078
 Total fragments: 1410304
Proteins after disorder filtering: 3399
 Total fragments: 139578
Proteins after pattern filtering: 1640
 Total fragments: 15425
Proteins after MINT filtering: 49
 Total fragments: 1020


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.06

-0.96

0.00
Best peptides

RPWKCRMK

0.00

-5.30

-4.34
         
Interactors      
Q06604

FEKGPRMP

6.79

-5.74

-4.78

NEEKPLLP

7.08

-4.32

-3.36

PPSPPAKR

7.76

-7.04

-6.08
Q12365

IPFIPPQE

7.53

-6.90

-5.94

KDIPGKFP

8.78

-3.29

-2.33

VPREPLRN

11.03

-7.61

-6.65
P40072

TPSASPML

7.72

-4.70

-3.74

AAPPTTKP

10.15

-3.30

-2.34

PPTTKPGT

10.97

2.66

3.62
P43603

RFTAPTSP

10.29

-5.07

-4.11

APTSPSTS

11.27

-4.43

-3.47

FTAPTSPS

12.12

0.77

1.73
P32628

EPPIAPES

7.99

-5.45

-4.49

PPIAPESA

11.27

-5.44

-4.48

PIAPESAT

15.44

0.23

1.19
Q12242

GTKPCDVP

10.70

-2.34

-1.38

KPCDVPNN

10.71

-4.50

-3.54

PCDVPNNG

12.76

-4.55

-3.59
P38266

MPPPKPFR

5.69

1.70

2.66

FPPPPLKP

6.26

-7.64

-6.68

YPIEPSLD

6.41

-5.11

-4.15
P15891

TPEKKPKE

6.87

0.37

1.33

PPLPSRNV

7.88

-4.44

-3.48

TPSPAPAA

7.96

-4.84

-3.88
P53169

VPIMPTLP

7.69

-7.39

-6.43

MPTLPPRP

7.98

-8.34

-7.38

ANSVPIMP

9.73

-4.27

-3.31
P39692

KLPPSPKQ

7.79

-3.61

-2.65

SPKQPVIM

8.58

-4.93

-3.97

LPPSPKQP

10.05

-5.94

-4.98
P17555

RPKKPSTL

6.25

-7.28

-6.32

PPPPAPPA

8.48

-5.96

-5.00

PPPRPKKP

9.23

-8.17

-7.21
Q12344

PPLPPRQN

7.42

-6.28

-5.32

SPKLPPRG

10.03

-6.24

-5.28

SPPLPPRQ

10.03

-6.70

-5.74
Q03780

RPPPPPMD

4.79

-8.29

-7.33

RSRPPPPP

9.02

-6.42

-5.46

IPPRSPNR

9.16

-5.21

-4.25
P53316

MPMFPSFG

6.58

-6.08

-5.12

IPQVPPVP

7.96

-5.92

-4.96

VPPVPYII

8.84

-6.75

-5.79
P32190

RPSTAPAR

5.94

-6.46

-5.50

RRPSTAPA

10.97

-1.05

-0.09

LRRPSTAP

11.32

-3.18

-2.22
P13186

PPIPAALP

6.02

-6.47

-5.51

RPPIPAAL

7.15

-7.71

-6.75

NIPLTPLA

8.77

0.22

1.18
P40325

QPGDPRLG

7.74

-6.59

-5.63

PPRPAANL

7.95

-5.02

-4.06

RPQQNPSL

8.08

-1.54

-0.58
P07278

TPPLPMHF

8.97

-5.50

-4.54

KTSTPPLP

10.80

-4.88

-3.92

TSTPPLPM

12.12

-3.09

-2.13
P47129

KPNPPPNR

7.57

-6.63

-5.67

LPNRKPNP

9.50

3.33

4.29

PPLLPPRN

9.58

-7.26

-6.30
P47029

HPTPPSLK

7.10

-4.57

-3.61

SPITSPMS

8.04

-4.40

-3.44

GPKLPNLP

8.98

-6.12

-5.16
Q12168

DPYFPQFR

8.40

-5.82

-4.86

PPLPPRAN

8.63

-7.46

-6.50

HPVPKPNI

8.65

4.22

5.18
P08458

TNLPKRKP

8.09

3.41

4.37

PKRKPPKL

9.72

-5.73

-4.77

LPKRKPPK

10.17

0.43

1.39
Q12496

PEIPSNIP

9.14

-2.16

-1.20

NIPKKRPF

9.46

4.02

4.98

PSNIPKKR

9.78

-5.70

-4.74
P32793

GPTHPSNM

10.34

-4.54

-3.58

PTHPSNMS

11.89

-3.47

-2.51

GHGPTHPS

12.21

1.54

2.50
P36006

PPPPPPMG

7.38

-7.29

-6.33

QPKDPKFE

8.89

-6.08

-5.12

IPIPPPPP

9.01

-6.50

-5.54
P32790

PPIKPPRP

8.25

-8.14

-7.18

APLDPFKT

8.74

-5.18

-4.22

LPPIKPPR

8.93

0.78

1.74
Q08412

LPTQPVRK

9.06

-7.50

-6.54

EDVPPQLP

10.17

-5.28

-4.32

PPQLPTRT

10.50

-7.22

-6.26
Q06440

DRTPKVEP

12.23

3.49

4.45

TPKVEPSK

12.59

-0.29

0.67

RTPKVEPS

13.11

-3.68

-2.72
P38750

FPHNAPAS

6.90

-5.71

-4.75

RSPPGVFP

7.72

-4.20

-3.24

PPILPRTT

8.44

-6.31

-5.35
P26570

MEPKSPIL

6.32

-3.79

-2.83

TPSKPNLE

7.85

-6.05

-5.09

DPSTPSKP

9.30

-5.69

-4.73
P31374

KPGTPVFP

7.62

-6.14

-5.18

TPVFPNLD

8.49

-5.94

-4.98

SPERPSFR

8.73

-5.97

-5.01
P38237

PPNVPKKD

8.80

-6.91

-5.95

IPSKPENT

8.81

-5.85

-4.89

NFQIPSKP

9.29

-5.21

-4.25
P34223

ESSPAEVP

9.63

-3.46

-2.50

MPDNEPKQ

10.16

0.21

1.17

SPAEVPKN

10.84

-3.12

-2.16
P53118

PHDLPSHL

10.50

-3.35

-2.39

VENPHDLP

13.56

3.66

4.62
P53933

RPPPPPIP

5.08

-7.92

-6.96

RVAPPPLP

7.71

-7.04

-6.08

PPIPSTQK

8.18

-3.86

-2.90
P33400

QPPNAPSY

8.61

-4.14

-3.18

PPNAPSYQ

9.08

-5.63

-4.67

PPLPVGIS

10.31

-3.66

-2.70
Q04439

KPKEPMFE

7.53

-6.29

-5.33

RPSPPTAA

7.64

-6.74

-5.78

PPPPSSKP

7.66

-5.01

-4.05
P33338

TPTPPVVA

8.39

-5.77

-4.81

ARTPARTP

8.67

-5.07

-4.11

TPTPTPPV

9.17

-0.58

0.38
Q12446

PPPPAFLT

6.27

-7.15

-6.19

PPPPASLG

6.54

-6.23

-5.27

RPVPPPPP

6.82

-7.69

-6.73
Q04322

TPSKSPTS

8.12

-4.16

-3.20

PPLPPRAD

8.76

-5.81

-4.85

PPTLPPRR

9.19

-7.46

-6.50
P39940

PRLPSSLD

9.78

-2.76

-1.80

TWDDPRLP

9.83

-4.59

-3.63

DPRLPSSL

10.65

-4.67

-3.71
P53901

RPIPPLPT

7.59

-6.65

-5.69

SPKLPPLP

7.78

-6.20

-5.24

MRPIPPLP

7.79

-6.74

-5.78
P38990

IPSPAKNP

7.61

-5.63

-4.67

SPIRPVLP

8.96

-5.83

-4.87

SPAKNPNA

9.87

0.41

1.37
P25693

RPIPTIKP

4.62

-2.29

-1.33
P25333

YPEGAPTS

7.20

-3.66

-2.70

TPAPTPTA

8.94

0.09

1.05

AITPAPTP

9.52

-4.05

-3.09
P25558

RHPKSPVK

5.38

-4.65

-3.69

SPVKKPMT

6.59

1.92

2.88

HPKSPVKK

9.01

-3.82

-2.86
P37370

RPHMPSVR

5.12

-8.67

-7.71

PPLPAAMS

6.12

-6.56

-5.60

NPPQAPPP

7.42

-5.04

-4.08
Q08446

HSPISPLK

8.45

-3.41

-2.45

SSHSPISP

13.58

-1.61

-0.65
Q02209

PESKPNVN

9.20

-5.05

-4.09

GPESKPNV

11.00

2.61

3.57

YKGPESKP

11.97

-2.20

-1.24

 


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