ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-7.PDB
Scoring matrix: RVS167_FMK-SSH-7_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.31
Foldx random average score for Saccharomyces cerevisiae: 9.036

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181364
Proteins after random average filtering: 5078
 Total fragments: 936042
Proteins after disorder filtering: 3116
 Total fragments: 47422
Proteins after pattern filtering: 1541
 Total fragments: 10360
Proteins after MINT filtering: 49
 Total fragments: 817


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

11.31

-3.26

0.00
Best peptides

MFPIPPWR

0.00

-6.36

-3.10
         
Interactors      
Q06604

PPSPPAKR

5.15

-7.32

-4.06

GPRMPSRG

5.95

-6.54

-3.28

KGPRMPSR

6.05

-5.56

-2.30
Q12365

IPFIPPQE

4.60

-5.85

-2.59

VPREPLRN

5.57

-6.69

-3.43

IVPREPLR

5.80

-4.47

-1.21
P40072

TPSASPML

7.61

-3.97

-0.71

PSASPMLD

7.85

-4.89

-1.63

PTTKPGTN

8.29

-5.37

-2.11
P43603

RFTAPTSP

8.07

-4.32

-1.06

APTSPSTS

8.92

-3.38

-0.12
P32628

EPPIAPES

7.79

-5.27

-2.01

PPIAPESA

8.73

-4.96

-1.70
Q12242

KPCDVPNN

8.07

-4.33

-1.07

PCDVPNNG

8.24

-5.34

-2.08

TKPCDVPN

8.63

-3.64

-0.38
P38266

MPPPKPFR

2.45

-9.68

-6.42

QPPPKPFR

3.23

-7.89

-4.63

SFPPPPLK

3.57

-5.69

-2.43
P15891

APPPPPRR

4.17

-7.39

-4.13

PPPPPRRA

4.99

-8.21

-4.95

TPEKKPKE

5.22

-5.56

-2.30
P53169

VPIMPTLP

5.12

-7.98

-4.72

MPTLPPRP

5.69

-7.77

-4.51

IMPTLPPR

6.61

-6.02

-2.76
P39692

MKLPPSPK

5.03

-6.81

-3.55

KLPPSPKQ

5.99

-5.30

-2.04

PKQPVIMS

6.64

-6.76

-3.50
P17555

KSGPPPRP

5.66

-7.05

-3.79

PPPRPKKP

5.82

-7.24

-3.98

GPPPRPKK

6.27

-7.13

-3.87
Q12344

PPLPPRQN

6.34

-6.68

-3.42

SPPLPPRQ

6.67

-6.29

-3.03

TTSSPPLP

7.21

-4.97

-1.71
Q03780

RPPPPPMD

4.29

-7.08

-3.82

PPPPMDMK

4.78

-7.71

-4.45

APDIPPRS

4.87

-6.97

-3.71
P53316

MPMFPSFG

3.90

-8.44

-5.18

VPPVPYII

4.97

-6.72

-3.46

QVPPVPYI

5.10

-5.51

-2.25
P32190

PSTAPARE

7.34

-5.56

-2.30

RPSTAPAR

8.60

-4.63

-1.37
P13186

RPPIPAAL

5.92

-6.05

-2.79

IPMSPNYG

6.27

-5.29

-2.03

PSYVPNRV

6.43

-6.77

-3.51
P40325

QPPRPPRP

4.23

-7.44

-4.18

QPRPPPRP

4.69

-7.48

-4.22

RPPPRPQQ

5.77

-7.36

-4.10
P07278

KTSTPPLP

6.05

-6.23

-2.97

TPPLPMHF

7.35

-5.89

-2.63

STPPLPMH

7.44

-6.92

-3.66
P47129

KPNPPPNR

5.33

-6.63

-3.37

PNPPPNRS

6.44

-6.10

-2.84

TSGPPLLP

6.61

-6.01

-2.75
P47029

HPTPPSLK

4.55

-6.88

-3.62

PRDPPSYK

4.94

-7.12

-3.86

ILPRDPPS

6.81

-5.29

-2.03
Q12168

IPPPVPNR

5.60

-4.64

-1.38

NRGPPPLP

5.76

-6.59

-3.33

PPPVPNRP

5.78

-7.06

-3.80
P08458

PKRKPPKL

5.07

-6.54

-3.28

TNLPKRKP

6.98

-6.69

-3.43

NLPKRKPP

7.95

-6.27

-3.01
Q12496

IPKKRPFL

4.68

-8.30

-5.04

PSNIPKKR

5.30

-7.09

-3.83

IPSNIPKK

5.32

-5.02

-1.76
P32793

HGPTHPSN

8.75

-2.97

0.29

GPTHPSNM

8.80

-3.75

-0.49

PTHPSNMS

8.83

-4.82

-1.56
P36006

PPPPPPMG

4.66

-7.74

-4.48

IPPPPPPM

5.30

-5.41

-2.15

QPKDPKFE

5.88

-6.39

-3.13
P32790

PPAMPARP

5.65

-7.13

-3.87

PPIKPPRP

5.77

-7.71

-4.45

EGPPPAMP

6.49

-6.78

-3.52
Q08412

QPLPPEPL

6.16

-5.55

-2.29

ELPTQPVR

6.56

-4.72

-1.46

PLPPEPLD

6.95

-5.51

-2.25
Q06440

RTPKVEPS

7.74

-4.82

-1.56

DRTPKVEP

8.46

-3.28

-0.02

TPKVEPSK

8.56

-3.00

0.26
P38750

PGVFPVRG

6.60

-6.20

-2.94

TFPHNAPA

7.03

-1.73

1.53

PASSPAYT

7.81

-4.94

-1.68
P26570

TPSKPNLE

5.16

-4.90

-1.64

MEPKSPIL

6.05

-5.40

-2.14

EPKSPILK

6.24

-5.51

-2.25
P31374

TKPPPPLD

4.52

-5.70

-2.44

SPERPSFR

5.28

-6.91

-3.65

TPVFPNLD

5.60

-4.38

-1.12
P38237

NFQIPSKP

5.23

-5.99

-2.73

PPNVPKKD

6.04

-6.61

-3.35

PFVPPPNV

6.10

-4.92

-1.66
P34223

MPDNEPKQ

6.89

-5.65

-2.39

SPAEVPKN

7.36

-4.55

-1.29

PMPDNEPK

7.91

-3.39

-0.13
P53118

VENPHDLP

6.75

-5.12

-1.86
P53933

RPPPPPIP

5.37

-7.26

-4.00

RRPPPPPI

5.41

-6.67

-3.41

RVAPPPLP

5.74

-6.92

-3.66
P33400

PPNAPSYQ

6.42

-6.48

-3.22

ILPPLPVG

6.80

-5.41

-2.15

QILPPLPV

6.94

-5.41

-2.15
Q04439

APPPPGMQ

5.14

-7.11

-3.85

KPKEPMFE

5.45

-6.86

-3.60

KPAPPPPG

5.84

-6.48

-3.22
P33338

TPTPPVVA

6.58

-4.80

-1.54

PARTPART

7.23

-5.86

-2.60

PTPTPPVV

7.48

-5.29

-2.03
Q12446

VPPPPPMR

3.27

-8.46

-5.20

APPPPPRR

4.17

-7.39

-4.13

PFPIPEIP

4.73

-6.23

-2.97
Q04322

PPTLPPRR

6.19

-7.47

-4.21

PTLPPRRI

6.20

-7.61

-4.35

SPPLPPRA

6.77

-6.17

-2.91
P39940

WDDPRLPS

7.70

-5.95

-2.69

TWDDPRLP

7.80

-5.22

-1.96

PRLPSSLD

7.97

-4.71

-1.45
P53901

MRPIPPLP

2.48

-8.11

-4.85

PLPPIPTR

6.06

-6.96

-3.70

AMRPIPPL

6.24

-6.93

-3.67
P38990

VSSVPNLP

6.04

-6.99

-3.73

QPSPIRPV

6.42

-5.88

-2.62

SPIRPVLP

6.43

-6.43

-3.17
P25693

RPIPTIKP

8.12

-5.41

-2.15
P25333

ITPAPTPT

7.81

-4.50

-1.24

TPAPTPTA

8.63

-2.00

1.26
P25558

SPVKKPMT

5.83

-7.23

-3.97

HPKSPVKK

6.02

-5.19

-1.93

KSPVKKPM

6.19

-6.41

-3.15
P37370

MPKPRPFQ

4.03

-9.36

-6.10

QMPKPRPF

4.39

-7.49

-4.23

APPIPGMG

4.65

-6.92

-3.66
Q08446

HSPISPLK

6.00

-4.77

-1.51

SHSPISPL

8.99

-4.24

-0.98
Q02209

PESKPNVN

7.11

-5.46

-2.20

YKGPESKP

7.33

-5.83

-2.57

 


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