ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-5.PDB
Scoring matrix: RVS167_FMK-SSH-5_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.82
Foldx random average score for Saccharomyces cerevisiae: 18.333

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171208
Proteins after random average filtering: 5078
 Total fragments: 1018241
Proteins after disorder filtering: 3052
 Total fragments: 51976
Proteins after pattern filtering: 1576
 Total fragments: 12091
Proteins after MINT filtering: 46
 Total fragments: 756


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.82

-1.90

0.00
Best peptides

FYNWPLKDHF

0.00

-6.83

-4.93
         
Interactors      
Q06604

MKNKPKPTPP

9.75

-3.04

-1.14

TMKNKPKPTP

11.66

-6.40

-4.50

RYSNIPSSKP

11.72

-5.44

-3.54
Q12365

QIPFIPPQED

13.00

-6.03

-4.13

DIPGKFPSPL

13.79

-7.18

-5.28

KDIPGKFPSP

16.11

-1.73

0.17
P40072

PSASPMLDAA

16.39

-3.69

-1.79

LDAAPPTTKP

16.63

-6.40

-4.50
P43603

TAPTSPSTSS

16.57

-2.84

-0.94

QGRFTAPTSP

17.19

-4.14

-2.24

GRFTAPTSPS

17.91

-3.61

-1.71
P08458

VMTNLPKRKP

12.69

-9.27

-7.37

PKRKPPKLQG

12.77

-4.43

-2.53

MTNLPKRKPP

12.91

-6.61

-4.71
P53901

NYNQPPLPPI

10.70

-5.76

-3.86

MRPIPPLPTE

11.11

-6.25

-4.35

LNSPKLPPLP

11.78

-5.50

-3.60
Q04322

KNDQAPLDRP

13.34

-7.13

-5.23

STPPTLPPRR

14.46

-5.82

-3.92

NDQAPLDRPQ

14.81

-3.77

-1.87
P38266

PKSFPPPPLK

8.82

-5.63

-3.73

MKGEVLPGHP

9.08

-6.66

-4.76

FLPPPKPFRH

9.50

-7.59

-5.69
P15891

KKSFTPSKSP

9.29

-5.70

-3.80

IISPKPFSKP

12.78

-8.32

-6.42

RSSAAPPPPP

13.57

-6.36

-4.46
P53169

IMPTLPPRPY

9.63

-9.75

-7.85

PIMPTLPPRP

12.78

-8.67

-6.77

YSPAQPSASL

16.18

-4.36

-2.46
P39692

VMKLPPSPKQ

11.53

-7.26

-5.36

MKLPPSPKQP

14.15

-4.13

-2.23

KLPPSPKQPV

14.56

-7.31

-5.41
P17555

SKSGPPPRPK

10.67

-5.61

-3.71

PRPKKPSTLK

13.50

-4.85

-2.95

AAPAPPPPPP

13.52

-7.29

-5.39
Q12344

TTSSPPLPPR

13.65

-5.10

-3.20

ATSTSPKLPP

14.12

-6.36

-4.46

PTTSSPPLPP

14.72

-5.37

-3.47
P53316

FIPQVPPVPY

7.66

-9.47

-7.57

MMPMFPSFGF

8.36

-8.08

-6.18

PYIIPPQNPA

11.94

-4.63

-2.73
P32190

SGLRRPSTAP

15.87

-5.01

-3.11

RRPSTAPARE

16.57

-5.88

-3.98
P13186

FKAPSYVPNR

11.74

-4.45

-2.55

NIPLTPLATN

12.75

-5.38

-3.48

PIPAALPPSD

13.10

-5.65

-3.75
P40325

SLPWTYPPRF

6.70

-8.19

-6.29

PLYVQPGDPR

13.26

-5.37

-3.47

QQNPSLPWTY

13.42

-3.73

-1.83
P07278

KTSTPPLPMH

12.31

-6.71

-4.81

TSTPPLPMHF

12.38

-5.73

-3.83
P47129

RKPNPPPNRS

11.21

-5.44

-3.54

TLPNRKPNPP

13.64

-3.24

-1.34

NRKPNPPPNR

14.22

-6.92

-5.02
P47029

ILPRDPPSYK

12.08

-8.35

-6.45

SKHPTPPSLK

12.29

-4.63

-2.73

SLNLSPLGAP

12.46

-6.82

-4.92
Q12168

NRGPPPLPPR

12.46

-6.14

-4.24

DNDDPYFPQF

12.80

-8.22

-6.32

TTNRGPPPLP

13.88

-7.56

-5.66
Q03780

IKRSRPPPPP

10.08

-6.28

-4.38

KRSRPPPPPM

10.41

-8.77

-6.87

KIKRSRPPPP

11.97

-6.81

-4.91
Q12496

PSNIPKKRPF

12.55

-4.23

-2.33

IPSNIPKKRP

17.60

-8.96

-7.06

SNIPKKRPFL

18.02

-3.17

-1.27
P32793

GHGPTHPSNM

15.82

-4.42

-2.52

SLGHGPTHPS

16.45

-3.41

-1.51

HGPTHPSNMS

16.78

-2.60

-0.70
P36006

NIPIPPPPPP

10.20

-7.01

-5.11

PMGQPKDPKF

11.00

-6.10

-4.20

PKDPKFEAAY

12.69

-3.86

-1.96
P32790

SSAPAPLDPF

13.47

-5.99

-4.09

SAPAPLDPFK

13.75

-6.50

-4.60

DEEGPPPAMP

15.56

-4.70

-2.80
Q08412

KKKWQPLPPE

7.81

-3.89

-1.99

KKWQPLPPEP

10.26

-6.61

-4.71

GKDIELPTQP

11.68

-3.93

-2.03
Q06440

KKDRTPKVEP

11.29

-5.75

-3.85
P38750

HLGLPHNLPH

11.46

-6.37

-4.47

GLPHNLPHNH

12.71

-5.06

-3.16

SLRSPPGVFP

13.98

-7.46

-5.56
P26570

LLWSDPTDSP

12.76

-7.64

-5.74

AYSTPLNSPG

13.80

-5.19

-3.29

PKSPILKTNN

14.00

-4.13

-2.23
P31374

FRKTKPPPPL

10.33

-9.89

-7.99

LLEPTPDDLP

10.59

-9.33

-7.43

RKTKPPPPLD

10.61

-5.85

-3.95
P38237

PFVPPPNVPK

14.16

-4.85

-2.95

DLNDPFVPPP

14.54

-4.85

-2.95

FQIPSKPENT

15.20

-4.17

-2.27
P34223

LEVTDPSDPN

12.92

-4.90

-3.00

QEQPMPDNEP

16.46

-3.97

-2.07

PAEVPKNETP

16.64

-1.42

0.48
P53118

ENPHDLPSHL

15.21

-3.64

-1.74

SVENPHDLPS

16.97

-4.75

-2.85

ESVENPHDLP

16.97

-5.15

-3.25
P53933

AKRVAPPPLP

10.81

-5.52

-3.62

RRRPPPPPIP

11.71

-8.58

-6.68

RTRRRPPPPP

12.20

-7.81

-5.91
P33400

QILPPLPVGI

13.60

-6.80

-4.90

SYVQPPNAPS

13.89

-3.35

-1.45

TSPQILPPLP

15.18

-5.81

-3.91
Q04439

KKPAPPPPGM

9.95

-6.70

-4.80

NIPPPPPPPP

11.42

-7.65

-5.75

QANIPPPPPP

12.68

-7.90

-6.00
P33338

LSWSGPLTPP

12.56

-7.88

-5.98

PLSWSGPLTP

14.09

-5.18

-3.28

SWSGPLTPPT

16.44

-2.14

-0.24
Q12446

RLPAPPPPPR

9.99

-8.28

-6.38

TKHKAPPPPP

10.58

-5.35

-3.45

NRPVPPPPPM

11.22

-7.06

-5.16
P39940

TWDDPRLPSS

15.85

-2.75

-0.85

PSSSPHSQAP

16.27

-5.80

-3.90

WDDPRLPSSL

16.39

-7.87

-5.97
P38990

NLPSAPSSTR

12.23

-5.15

-3.25

SRNQNLPKIP

13.10

-4.52

-2.62

RNQNLPKIPN

14.41

-6.36

-4.46
P25333

NTAITPAPTP

15.18

-5.69

-3.79

KYPEGAPTSG

15.87

-4.44

-2.54

AITPAPTPTA

16.50

-3.13

-1.23
P25558

ELPNTPRSIN

14.39

-7.37

-5.47

RHPKSPVKKP

15.21

-5.01

-3.11

PKSPVKKPMT

15.21

-1.60

0.30
P37370

LAPLPPPPPP

10.01

-7.99

-6.09

SMPAPPPPPP

11.04

-8.32

-6.42

SIPLAPLPPP

11.35

-7.14

-5.24
Q08446

NSSHSPISPL

17.87

-4.25

-2.35
Q02209

IYKGPESKPN

14.78

-3.52

-1.62

KGPESKPNVN

16.44

-1.91

-0.01

 


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