ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-26.PDB
Scoring matrix: RVS167_FMK-SSH-26_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.02
Foldx random average score for Saccharomyces cerevisiae: 10.811

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176286
Proteins after random average filtering: 5077
 Total fragments: 878654
Proteins after disorder filtering: 2922
 Total fragments: 39656
Proteins after pattern filtering: 1500
 Total fragments: 10535
Proteins after MINT filtering: 49
 Total fragments: 838


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.02

-1.92

0.00
Best peptides

DRMRKMWPF

0.00

-7.18

-5.26
         
Interactors      
Q06604

PSPPAKRIP

6.45

-7.74

-5.82

PPLPTRRDH

6.97

-7.68

-5.76

SFEKGPRMP

7.30

-5.86

-3.94
Q12365

KDIPGKFPS

7.22

-5.25

-3.33

IVPREPLRN

7.86

-8.52

-6.60

VPREPLRNE

8.89

-6.75

-4.83
P40072

AAPPTTKPG

9.50

-6.92

-5.00

PSASPMLDA

9.95

-5.36

-3.44
P40325

QPPRPPRPA

5.72

-6.98

-5.06

QPRPPPRPQ

6.05

-7.88

-5.96

QSRPHQRPS

6.27

-7.12

-5.20
Q12532

PFKPYINGG

10.11

-4.96

-3.04
P32628

EPPIAPESA

10.33

-5.40

-3.48
Q12242

TKPCDVPNN

10.02

-5.39

-3.47
P38266

NIMPPPKPF

4.97

-6.86

-4.94

PPKPFRRSQ

5.35

-6.88

-4.96

NFQPPPKPF

5.64

-6.02

-4.10
P15891

PPPPPRRAT

5.30

-9.35

-7.43

APPPPPRRA

5.95

-8.30

-6.38

RATPEKKPK

7.52

-6.17

-4.25
P53169

MPTLPPRPY

6.80

-5.63

-3.71

NSVPIMPTL

7.46

-7.54

-5.62

PIMPTLPPR

8.79

-7.30

-5.38
P39692

KLPPSPKQP

7.31

-7.30

-5.38

SPKQPVIMS

8.28

-4.23

-2.31

PKQPVIMSG

8.48

-7.04

-5.12
P17555

KSGPPPRPK

6.44

-6.23

-4.31

SGPPPRPKK

6.65

-7.49

-5.57

PPPRPKKPS

6.99

-7.39

-5.47
Q12344

SPKLPPRGK

6.20

-6.57

-4.65

SPPLPPRQN

6.86

-6.66

-4.74

SSPPLPPRQ

7.56

-6.92

-5.00
Q03780

RPPPPPMDM

6.08

-8.73

-6.81

RSRPPPPPM

6.61

-7.55

-5.63

TSAPDIPPR

7.99

-7.40

-5.48
P53316

WMMPMFPSF

7.16

-7.07

-5.15

PPVPYIIPP

7.24

-5.91

-3.99

MPMFPSFGF

7.82

-5.29

-3.37
P32190

RRPSTAPAR

10.16

-5.13

-3.21

PSTAPARET

10.56

-5.56

-3.64
P13186

QEPLPEREP

7.83

-7.78

-5.86

SSIPMSPNY

8.38

-4.45

-2.53

PPIPAALPP

8.58

-5.95

-4.03
P07278

STPPLPMHF

5.08

-8.03

-6.11

TSTPPLPMH

9.26

-5.33

-3.41

KTSTPPLPM

9.63

-5.18

-3.26
P47129

PNPPPNRSQ

7.41

-7.77

-5.85

SGPPLLPPR

7.79

-7.31

-5.39

TSGPPLLPP

8.55

-5.55

-3.63
P47029

SKHPTPPSL

6.81

-6.28

-4.36

ILPRDPPSY

7.49

-7.45

-5.53

DGHPASFPK

8.06

-4.62

-2.70
Q12168

VQHPVPKPN

7.61

-5.21

-3.29

PPPLPPRAN

7.76

-6.68

-4.76

RGPPPLPPR

7.80

-7.74

-5.82
P08458

TNLPKRKPP

6.53

-6.82

-4.90

LPKRKPPKL

7.57

-6.73

-4.81

NLPKRKPPK

8.22

-6.76

-4.84
Q12496

SNIPKKRPF

1.92

-6.72

-4.80

NIPKKRPFL

7.58

-7.39

-5.47

PEIPSNIPK

8.24

-5.48

-3.56
P32793

PTHPSNMSN

9.77

-6.39

-4.47
P36006

PIPPPPPPM

7.42

-8.42

-6.50

IPIPPPPPP

7.82

-6.41

-4.49

PPPPPPMGQ

8.00

-7.44

-5.52
P32790

PPIKPPRPT

6.09

-6.04

-4.12

EGPPPAMPA

7.68

-7.90

-5.98

GPPPAMPAR

8.12

-7.73

-5.81
Q08412

EDVPPQLPT

6.48

-5.65

-3.73

KKKWQPLPP

7.06

-6.25

-4.33

DVPPQLPTR

8.19

-8.19

-6.27
Q06440

DRTPKVEPS

8.79

-4.36

-2.44

RTPKVEPSK

8.80

-7.09

-5.17

KDRTPKVEP

10.32

-5.07

-3.15
P38750

PGVFPVRGM

6.01

-6.50

-4.58

RSPPGVFPV

7.53

-6.97

-5.05

LPHNLPHNH

8.66

-3.49

-1.57
P26570

MEPKSPILK

7.78

-5.90

-3.98

EPKSPILKT

8.31

-6.34

-4.42

DPTDSPNEW

9.04

-3.70

-1.78
P31374

TKPPPPLDF

4.85

-7.67

-5.75

PERPSFRQP

7.37

-7.71

-5.79

NISPERPSF

7.93

-6.50

-4.58
P38237

VPPPNVPKK

8.73

-7.17

-5.25

FQIPSKPEN

9.13

-5.06

-3.14

FVPPPNVPK

9.26

-5.04

-3.12
P34223

ESSPAEVPK

9.39

-4.97

-3.05

SPAEVPKNE

9.88

-4.33

-2.41

SSPAEVPKN

10.15

-5.47

-3.55
P53118

ENPHDLPSH

9.55

-6.55

-4.63

VENPHDLPS

10.43

-5.62

-3.70

NPHDLPSHL

10.50

-2.56

-0.64
P53933

RPPPPPIPS

6.63

-6.85

-4.93

RRRPPPPPI

7.01

-7.68

-5.76

TRRRPPPPP

7.07

-5.89

-3.97
P33400

STSPQILPP

7.87

-6.07

-4.15

ILPPLPVGI

8.28

-6.01

-4.09

TSPQILPPL

8.28

-6.06

-4.14
Q04439

SSKPKEPMF

5.91

-6.63

-4.71

SGSPSELPL

7.62

-6.16

-4.24

SKKPAPPPP

7.74

-6.37

-4.45
P33338

TPTPPVVAE

9.21

-4.79

-2.87

TPARTPTPT

9.66

-5.92

-4.00

TPTPTPPVV

9.75

-4.23

-2.31
Q12446

PPPPPRRGP

5.22

-9.98

-8.06

PPPPPMRTT

5.24

-9.14

-7.22

APPPPPRRG

6.11

-9.63

-7.71
Q04322

SPPLPPRAD

6.79

-6.29

-4.37

DQAPLDRPQ

7.20

-8.01

-6.09

TSPPLPPRA

7.80

-7.05

-5.13
P39940

TTWDDPRLP

6.85

-4.83

-2.91

DDPRLPSSL

7.96

-5.57

-3.65

TWDDPRLPS

8.09

-5.07

-3.15
P53901

MAMRPIPPL

6.30

-7.34

-5.42

DPIILPPTF

6.64

-6.81

-4.89

SPKLPPLPT

7.75

-5.37

-3.45
P38990

NQPSPIRPV

7.08

-6.06

-4.14

TNQPSPIRP

7.10

-6.13

-4.21

SSVPNLPSA

8.76

-5.13

-3.21
P25693

NRPIPTIKP

10.09

-7.10

-5.18
P25333

TPAPTPTAS

10.59

-4.90

-2.98
P25558

ELPNTPRSI

6.29

-7.16

-5.24

PKSPVKKPM

7.47

-7.19

-5.27

SPVKKPMTS

7.63

-5.50

-3.58
P37370

SQMPKPRPF

2.01

-8.13

-6.21

PHMPSVRPA

5.65

-7.01

-5.09

SAPPPPPTL

6.90

-7.27

-5.35
Q08446

SSHSPISPL

8.94

-3.45

-1.53

NSSHSPISP

10.61

-3.90

-1.98
Q02209

PESKPNVNF

10.12

-4.03

-2.11

KGPESKPNV

10.15

-5.98

-4.06

 


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