ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-19.PDB
Scoring matrix: RVS167_FMK-SSH-19_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.23
Foldx random average score for Saccharomyces cerevisiae: 13.783

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176286
Proteins after random average filtering: 5078
 Total fragments: 1062821
Proteins after disorder filtering: 3182
 Total fragments: 60933
Proteins after pattern filtering: 1539
 Total fragments: 8434
Proteins after MINT filtering: 48
 Total fragments: 503


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.23

-0.76

0.00
Best peptides

RPFMHGILF

0.00

-1.46

-0.70
         
Interactors      
Q06604

PPSPPAKRI

9.06

-5.80

-5.04

GPRMPSRGR

9.41

-3.77

-3.01

EKGPRMPSR

10.38

-6.39

-5.63
Q12365

PGKFPSPLT

10.95

-3.26

-2.50

VPREPLRNE

11.30

-0.92

-0.16

VKDIPGKFP

11.75

-5.14

-4.38
P40072

PTTKPGTNS

11.54

-5.64

-4.88

NTPSASPML

12.09

-2.71

-1.95

DAAPPTTKP

12.43

-7.04

-6.28
P43603

APTSPSTSS

12.02

-0.30

0.46

RFTAPTSPS

12.38

-3.16

-2.40
P32628

PPIAPESAT

12.27

-3.51

-2.75
Q04322

STPPTLPPR

12.20

-2.88

-2.12

SSTPPTLPP

12.24

-4.89

-4.13

DQAPLDRPQ

12.43

-5.92

-5.16
P38266

QPQPPQPMQ

8.04

-4.35

-3.59

PPVPVRMQP

8.64

-3.45

-2.69

PPLKPGQKT

8.80

-2.54

-1.78
P15891

RATPEKKPK

10.29

-4.21

-3.45

RRATPEKKP

10.29

-5.85

-5.09

PPPPRRATP

11.19

-6.03

-5.27
P53169

SPAQPSASL

9.93

-0.86

-0.10

PAQPSASLT

10.78

-3.15

-2.39

VPIMPTLPP

11.15

-3.26

-2.50
P39692

SPKQPVIMS

9.52

-1.42

-0.66

PPSPKQPVI

9.62

-3.82

-3.06

MKLPPSPKQ

10.24

-5.49

-4.73
P17555

RPKKPSTLK

3.68

-2.98

-2.22

PPAPPASVF

9.18

-3.66

-2.90

SGPPPRPKK

9.56

-4.92

-4.16
Q12344

PPLPPRQNV

9.69

-5.86

-5.10

PKLPPRGKQ

10.64

-5.57

-4.81

STSPKLPPR

10.94

-6.87

-6.11
Q03780

PPPPPMDMK

8.14

-7.45

-6.69

DIPPRSPNR

10.98

-8.17

-7.41

PPPPMDMKS

11.26

-3.44

-2.68
P53316

MPMFPSFGF

10.28

-4.34

-3.58

WMMPMFPSF

10.52

-5.76

-5.00

VPPVPYIIP

11.48

-3.02

-2.26
P32190

RRPSTAPAR

10.22

-3.79

-3.03

GLRRPSTAP

13.32

-4.14

-3.38

LRRPSTAPA

13.41

-2.94

-2.18
P13186

RPPIPAALP

7.01

-5.02

-4.26

NNIPLTPLA

9.58

-4.94

-4.18

SSIPMSPNY

9.87

-4.71

-3.95
P40325

RPPRPAANL

8.04

-3.96

-3.20

PRPPPRPQQ

9.15

-7.47

-6.71

PPRPAANLA

9.62

-4.74

-3.98
P07278

TSTPPLPMH

9.89

-6.35

-5.59
P47129

SGPPLLPPR

11.46

-5.10

-4.34

PLLPPRNTM

12.10

-6.22

-5.46

SESTPTSGP

12.27

-4.96

-4.20
P47029

HPTPPSLKA

8.97

-1.71

-0.95

PRDPPSYKD

11.51

-4.92

-4.16

PNLPNDANL

12.12

-4.01

-3.25
Q12168

NDDPYFPQF

9.12

-4.83

-4.07

PPLPPRANV

9.48

-4.10

-3.34

VPNRPGGTT

9.79

-0.23

0.53
P08458

NLPKRKPPK

10.94

-6.99

-6.23

TNLPKRKPP

12.22

-6.23

-5.47

PKRKPPKLQ

13.52

-5.12

-4.36
Q12496

SNIPKKRPF

8.32

-4.93

-4.17

PEIPSNIPK

11.92

-4.37

-3.61

NIPKKRPFL

12.24

-5.66

-4.90
P32793

GPTHPSNMS

11.86

-1.44

-0.68
P36006

KPKNPGGLS

8.00

-1.50

-0.74

PPPPMGQPK

8.97

-4.34

-3.58

MGQPKDPKF

9.49

-5.67

-4.91
P32790

APAPLDPFK

11.18

-1.94

-1.18

PPAMPARPT

11.34

-4.63

-3.87

PPRPTSTTS

12.16

-1.37

-0.61
Q08412

QPLPPEPLD

7.78

-2.41

-1.65

IELPTQPVR

10.05

-4.32

-3.56

DVPPQLPTR

11.36

-5.87

-5.11
Q06440

RTPKVEPSK

11.22

-3.89

-3.13

DRTPKVEPS

12.41

-5.85

-5.09

KDRTPKVEP

13.45

-4.96

-4.20
P38750

LRSPPGVFP

9.42

-5.69

-4.93

SPPGVFPVR

11.00

-1.08

-0.32

LGLPHNLPH

11.56

-3.93

-3.17
P26570

PLNSPGLSK

10.26

-2.94

-2.18

TPSKPNLEV

11.41

-2.30

-1.54

VPDPSTPSK

11.82

-1.50

-0.74
P31374

SPERPSFRQ

8.52

-1.66

-0.90

SNKKPGTPV

9.14

-2.91

-2.15

LEPTPDDLP

10.77

-4.70

-3.94
P38237

FVPPPNVPK

11.19

-5.06

-4.30

IPSKPENTV

11.54

-3.25

-2.49

VPPPNVPKK

12.30

-2.08

-1.32
P34223

QPMPDNEPK

11.52

-1.44

-0.68

GESSPAEVP

13.21

-3.21

-2.45

ESSPAEVPK

13.32

-2.89

-2.13
P53118

SVENPHDLP

9.35

-5.93

-5.17

VENPHDLPS

11.92

-4.06

-3.30
P53933

PPLPNRQLP

7.86

-6.07

-5.31

PPPIPSTQK

9.76

-3.01

-2.25

VAPPPLPNR

11.49

-5.33

-4.57
P33400

HSTSPQILP

9.12

-3.62

-2.86

PPNAPSYQS

10.73

-2.26

-1.50

YVQPPNAPS

12.59

-4.66

-3.90
Q04439

SSKPKEPMF

6.48

-5.98

-5.22

APPPPGMQN

7.60

-4.48

-3.72

RPSPPTAAT

9.71

-2.03

-1.27
P33338

TPTPPVVAE

12.41

-1.52

-0.76

ARTPARTPT

12.48

-4.34

-3.58

RTPARTPTP

13.76

-6.39

-5.63
Q12446

RPLPQLPNR

7.72

-4.05

-3.29

PPPPPAFLT

8.01

-3.17

-2.41

PPPPPASLG

8.76

-5.64

-4.88
P39940

PSSSPHSQA

11.70

-2.52

-1.76

PRLPSSLDQ

12.08

-3.74

-2.98

DPRLPSSLD

13.01

-1.99

-1.23
P53901

RPIPPLPTE

8.34

-3.31

-2.55

PPIPTRDDM

10.69

-2.26

-1.50

PPLPTESEY

11.25

-4.42

-3.66
P38990

QPSPIRPVL

9.75

-1.75

-0.99

LPSAPSSTR

10.94

-2.39

-1.63

SSVPNLPSA

12.27

-2.37

-1.61
P25693

NRPIPTIKP

12.72

-6.15

-5.39
P25333

DKYPEGAPT

10.55

-2.79

-2.03

PEGAPTSGA

13.77

-2.54

-1.78
P25558

KSPVKKPMT

10.79

-6.43

-5.67

LPNTPRSIN

10.90

-2.33

-1.57

PVKKPMTSE

10.97

-4.75

-3.99
P37370

SPAPPLPLS

6.46

-1.48

-0.72

RPSPISPSI

7.49

-3.02

-2.26

AVTPGGPLP

7.52

-6.58

-5.82
Q08446

SHSPISPLK

7.67

-3.85

-3.09
Q02209

PESKPNVNF

9.60

-4.31

-3.55

IYKGPESKP

13.50

-3.85

-3.09

 


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