ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-16.PDB
Scoring matrix: RVS167_FMK-SSH-16_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.93
Foldx random average score for Saccharomyces cerevisiae: 15.282

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176286
Proteins after random average filtering: 5078
 Total fragments: 917038
Proteins after disorder filtering: 3174
 Total fragments: 61832
Proteins after pattern filtering: 1556
 Total fragments: 9271
Proteins after MINT filtering: 49
 Total fragments: 594


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.93

-1.15

0.00
Best peptides

FPFIRPIWM

0.00

0.61

1.76
         
Interactors      
Q06604

LLPTRPNKA

7.17

-5.09

-3.94

LPTRPNKAE

11.61

-4.49

-3.34

GPRMPSRGR

11.69

-6.32

-5.17
Q12365

IPFIPPQED

9.33

-5.88

-4.73

VKDIPGKFP

11.55

-4.52

-3.37

VPREPLRNE

13.36

-4.35

-3.20
P40072

PPTTKPGTN

11.63

-5.54

-4.39

TPSASPMLD

13.89

-3.20

-2.05

APPTTKPGT

14.77

-2.86

-1.71
P43603

TAPTSPSTS

13.22

-2.66

-1.51

GRFTAPTSP

13.89

-2.83

-1.68

APTSPSTSS

14.51

-3.67

-2.52
P32628

EPPIAPESA

8.89

-7.03

-5.88
Q12242

KPCDVPNNG

11.99

-4.03

-2.88
P38266

TPPRPPPSR

9.44

-5.97

-4.82

KPPVVPKKK

10.08

-6.23

-5.08

LKKKPPVVP

10.44

-5.35

-4.20
P15891

TPEKKPKEN

10.91

-4.78

-3.63

VPEDEPEGE

12.44

-3.36

-2.21

EPVKTPSPA

12.47

-4.39

-3.24
P53169

MPTLPPRPY

11.41

-6.79

-5.64

IMPTLPPRP

11.99

-4.82

-3.67

SVPIMPTLP

13.23

-5.45

-4.30
P39692

PSPKQPVIM

10.95

-3.91

-2.76

SPKQPVIMS

13.72

-3.00

-1.85

KLPPSPKQP

13.79

-4.21

-3.06
P17555

RPKKPSTLK

9.92

-6.08

-4.93

GPPPRPKKP

12.45

-5.33

-4.18

PPPRPKKPS

14.06

-4.03

-2.88
Q12344

SPPLPPRQN

12.70

-6.32

-5.17

SPKLPPRGK

12.74

-5.65

-4.50

PLPPRQNVA

13.21

-3.92

-2.77
Q03780

APDIPPRSP

9.27

-6.74

-5.59

IPPRSPNRN

10.06

-5.60

-4.45

RPPPPPMDM

10.49

-4.64

-3.49
P53316

VPYIIPPQN

9.01

-5.63

-4.48

IPQVPPVPY

10.17

-5.86

-4.71

MMPMFPSFG

10.52

-4.68

-3.53
P32190

RPSTAPARE

9.86

-4.13

-2.98

RRPSTAPAR

14.02

-2.87

-1.72

GLRRPSTAP

14.72

-4.93

-3.78
P13186

LPEREPPTY

8.76

-7.18

-6.03

RPPIPAALP

9.60

-7.55

-6.40

IPLTPLATN

12.63

-5.69

-4.54
P40325

RPHQRPSTM

5.62

-7.38

-6.23

LPWTYPPRF

8.64

-7.13

-5.98

RPPPRPQQN

9.24

-6.33

-5.18
P07278

KTSTPPLPM

12.67

-2.65

-1.50
P47129

RKPNPPPNR

8.77

-5.93

-4.78

TLPNRKPNP

10.14

-3.85

-2.70

LPNRKPNPP

10.40

-6.81

-5.66
P47029

LPRDPPSYK

9.47

-5.00

-3.85

KLPNLPNDA

9.54

-4.00

-2.85

ILPRDPPSY

9.82

-5.52

-4.37
Q12168

DDPYFPQFR

12.80

-2.79

-1.64

PPPLPPRAN

13.18

-6.62

-5.47

PVPNRPGGT

13.44

-0.11

1.04
P08458

NLPKRKPPK

10.43

-4.91

-3.76

TPITNPSSS

11.70

-4.51

-3.36

PKRKPPKLQ

12.18

-2.49

-1.34
Q12496

IPSNIPKKR

10.31

-4.47

-3.32

PSNIPKKRP

13.60

-5.11

-3.96
P32793

HGPTHPSNM

11.76

-4.16

-3.01

GPTHPSNMS

14.03

-3.68

-2.53

SLGHGPTHP

14.30

-4.10

-2.95
P36006

KPKNPGGLS

11.21

-4.11

-2.96

KSNKKPKNP

12.02

-5.02

-3.87

GQPKDPKFE

12.26

-2.73

-1.58
P32790

LPPIKPPRP

7.64

-8.86

-7.71

PPIKPPRPT

13.45

-3.71

-2.56

KPPRPTSTT

13.58

-4.82

-3.67
Q08412

ELPTQPVRK

10.95

-2.40

-1.25

LPTQPVRKN

12.32

-5.56

-4.41

GKNSRPQQP

12.65

-4.60

-3.45
Q06440

KDRTPKVEP

12.72

-5.21

-4.06

RTPKVEPSK

13.28

-4.95

-3.80
P38750

LPHNLPHNH

8.34

-5.03

-3.88

FPHNAPASS

9.54

-4.95

-3.80

PPGVFPVRG

12.32

-4.86

-3.71
P26570

MEPKSPILK

9.68

-1.93

-0.78

DPTDSPNEW

11.37

-3.92

-2.77

TPLNSPGLS

11.53

-3.28

-2.13
P31374

ISPERPSFR

10.17

-1.57

-0.42

TPDDLPPLK

11.20

-4.04

-2.89

FRKTKPPPP

11.73

-5.55

-4.40
P38237

PPPNVPKKD

12.14

-4.44

-3.29

DPFVPPPNV

12.74

-4.63

-3.48

PDLNDPFVP

12.95

-2.88

-1.73
P34223

MPDNEPKQG

11.13

-4.17

-3.02

LEVTDPSDP

12.60

-3.86

-2.71

SPAEVPKNE

13.14

-3.43

-2.28
P53118

ENPHDLPSH

14.17

-2.69

-1.54
P53933

PPPIPSTQK

10.08

-6.18

-5.03

RTRRRPPPP

10.73

-6.41

-5.26

RPPPPPIPS

12.12

-3.68

-2.53
P33400

SPQILPPLP

9.96

-6.50

-5.35

QPPNAPSYQ

10.10

-4.42

-3.27

SYVQPPNAP

14.11

-1.62

-0.47
Q04439

KPAPPPPGM

11.14

-5.46

-4.31

RHSKKPAPP

11.34

-5.07

-3.92

RQANIPPPP

11.88

-4.15

-3.00
P33338

PTPTPPVVA

13.59

-1.30

-0.15

TPARTPART

13.70

-3.80

-2.65

LSWSGPLTP

13.83

-2.52

-1.37
Q12446

PPPRRGPAP

10.16

-6.62

-5.47

NRNNRPVPP

10.43

-4.08

-2.93

IPEIPSTQS

10.74

-4.52

-3.37
Q04322

TPPTLPPRR

10.24

-4.97

-3.82

TPSKSPTSA

10.82

-5.35

-4.20

SPPLPPRAD

13.83

-5.17

-4.02
P39940

WDDPRLPSS

12.90

-3.58

-2.43
P53901

DPIILPPTF

7.92

-6.92

-5.77

LPPIPTRDD

10.57

-6.06

-4.91

MRPIPPLPT

11.73

-3.26

-2.11
P38990

PSPIRPVLP

8.31

-5.17

-4.02

RNQNLPKIP

10.77

-4.25

-3.10

SPAKNPNAD

11.76

-3.84

-2.69
P25693

NRPIPTIKP

12.48

-4.93

-3.78
P25333

YPEGAPTSG

13.89

-3.90

-2.75

TAITPAPTP

14.82

-3.41

-2.26
P25558

RHPKSPVKK

8.55

-3.60

-2.45

YNPSQPVTE

11.27

-2.98

-1.83

SPVKKPMTS

11.56

-4.80

-3.65
P37370

VPQNRPHMP

7.96

-5.39

-4.24

SPSINPPKQ

9.42

-5.58

-4.43

RPHMPSVRP

9.94

-7.72

-6.57
Q08446

NSSHSPISP

13.29

-2.68

-1.53
Q02209

GPESKPNVN

12.60

-3.84

-2.69

PESKPNVNF

12.80

-2.79

-1.64

 


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