ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-11.PDB
Scoring matrix: RVS167_FMK-SSH-11_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.6
Foldx random average score for Saccharomyces cerevisiae: 9.997

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2186442
Proteins after random average filtering: 5078
 Total fragments: 989546
Proteins after disorder filtering: 3312
 Total fragments: 69194
Proteins after pattern filtering: 1608
 Total fragments: 11045
Proteins after MINT filtering: 49
 Total fragments: 836


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.60

-1.21

0.00
Best peptides

YPPMIRF

0.00

-8.37

-7.16
         
Interactors      
Q06604

LPTRPNK

5.24

-5.17

-3.96

GPRMPSR

5.32

-5.52

-4.31

KPTPPSP

5.65

-4.67

-3.46
Q12365

IPFIPPQ

4.98

-4.50

-3.29

VPREPLR

6.33

-3.85

-2.64

QIPFIPP

7.71

-5.44

-4.23
P40072

APPTTKP

6.93

-4.20

-2.99

PPTTKPG

7.82

-4.90

-3.69

PSASPML

8.70

-2.86

-1.65
P43603

APTSPST

7.58

-3.66

-2.45

FTAPTSP

8.62

-3.33

-2.12
P32628

PPIAPES

8.72

-4.19

-2.98

EPPIAPE

9.00

-4.20

-2.99
Q12242

KPCDVPN

6.97

-5.18

-3.97

PCDVPNN

9.18

-3.17

-1.96
P38266

YPIEPSL

3.22

-6.73

-5.52

FPPPPLK

3.75

-5.61

-4.40

MPPPKPF

3.88

-6.25

-5.04
P15891

PPPPPRR

5.48

-5.66

-4.45

APPPPPR

5.59

-4.77

-3.56

TPEKKPK

5.91

-3.95

-2.74
P53169

VPIMPTL

4.47

-4.99

-3.78

MPTLPPR

5.94

-6.09

-4.88

SPAQPSA

7.09

-3.41

-2.20
P39692

SPKQPVI

6.41

-4.29

-3.08

LPPSPKQ

6.53

-4.52

-3.31

MKLPPSP

7.69

-3.73

-2.52
P17555

PPPRPKK

4.51

-5.23

-4.02

RPKKPST

4.58

-5.63

-4.42

APPPPPP

5.89

-4.65

-3.44
Q12344

PPLPPRQ

6.19

-5.00

-3.79

SPPLPPR

6.89

-5.10

-3.89

SPKLPPR

7.24

-5.12

-3.91
Q03780

RPPPPPM

3.33

-6.85

-5.64

APDIPPR

5.15

-5.32

-4.11

PPPPMDM

6.06

-6.74

-5.53
P53316

MPMFPSF

3.29

-5.93

-4.72

VPPVPYI

5.27

-3.99

-2.78

VPYIIPP

5.35

-5.26

-4.05
P32190

RRPSTAP

8.36

-3.26

-2.05

RPSTAPA

8.78

-4.83

-3.62

PSTAPAR

9.08

-2.89

-1.68
P13186

RPPIPAA

4.67

-5.78

-4.57

APSYVPN

5.57

-5.20

-3.99

IPMSPNY

6.42

-3.14

-1.93
P40325

RPPRPAA

4.59

-6.10

-4.89

QPPRPPR

5.03

-5.10

-3.89

RPQQNPS

5.58

-4.04

-2.83
P07278

PPLPMHF

5.52

-6.54

-5.33

TPPLPMH

7.27

-4.33

-3.12

STPPLPM

8.77

-5.76

-4.55
P47129

KPNPPPN

6.02

-5.30

-4.09

LPNRKPN

6.71

-5.30

-4.09

PPLLPPR

6.82

-6.17

-4.96
P47029

HPTPPSL

5.64

-5.29

-4.08

LPRDPPS

7.45

-4.63

-3.42

GPKLPNL

7.53

-4.97

-3.76
Q12168

PPPVPNR

5.56

-5.67

-4.46

IPPPVPN

5.82

-4.50

-3.29

DPYFPQF

6.15

-5.39

-4.18
P08458

LPKRKPP

6.01

-5.56

-4.35

TPITNPS

7.06

-1.93

-0.72

PKRKPPK

7.24

-4.44

-3.23
Q12496

IPKKRPF

4.39

-7.00

-5.79

IPSNIPK

5.22

-4.98

-3.77

PSNIPKK

7.33

-4.11

-2.90
P32793

GPTHPSN

7.42

-4.19

-2.98
P36006

PPPPPPM

4.76

-6.09

-4.88

IPPPPPP

5.30

-4.25

-3.04

IPIPPPP

5.70

-3.98

-2.77
P32790

PPAMPAR

5.05

-5.98

-4.77

KPPRPTS

5.20

-5.07

-3.86

PPIKPPR

5.25

-5.58

-4.37
Q08412

LPTQPVR

6.14

-4.78

-3.57

VPPQLPT

6.30

-4.41

-3.20

LPPEPLD

7.19

-3.85

-2.64
Q06440

RTPKVEP

8.36

-4.71

-3.50

PKVEPSK

8.59

-3.92

-2.71

TPKVEPS

9.38

-2.15

-0.94
P38750

LPHNLPH

6.73

-5.55

-4.34

PPILPRT

7.46

-6.04

-4.83

SPPGVFP

7.85

-4.14

-2.93
P26570

TPSKPNL

5.44

-4.54

-3.33

DPSTPSK

6.43

-4.04

-2.83

EPKSPIL

6.73

-3.55

-2.34
P31374

KPGTPVF

4.22

-5.61

-4.40

SPERPSF

4.28

-4.79

-3.58

PPPPLDF

5.20

-6.69

-5.48
P38237

PPPNVPK

5.49

-5.59

-4.38

PPNVPKK

5.57

-5.54

-4.33

VPPPNVP

6.18

-3.04

-1.83
P34223

SPAEVPK

6.44

-4.25

-3.04

MPDNEPK

7.39

-4.38

-3.17

PDNEPKQ

7.96

-4.95

-3.74
P53118

NPHDLPS

8.04

-5.33

-4.12

PHDLPSH

9.15

-4.77

-3.56
P53933

RPPPPPI

4.09

-6.16

-4.95

YPGNPTS

4.95

-5.67

-4.46

PPPIPST

5.63

-5.76

-4.55
P33400

PPLPVGI

6.11

-5.17

-3.96

PPNAPSY

6.76

-4.55

-3.34

SPQILPP

6.77

-4.56

-3.35
Q04439

KPKEPMF

4.28

-5.97

-4.76

APPPPGM

4.92

-5.43

-4.22

IPPPPPP

5.30

-4.25

-3.04
P33338

TPTPPVV

6.95

-2.88

-1.67

TPARTPT

7.05

-2.37

-1.16

TPARTPA

7.21

-1.92

-0.71
Q12446

FPFPVPQ

4.50

-5.63

-4.42

VPPPPPM

4.58

-4.64

-3.43

PPPPPAF

4.63

-5.87

-4.66
Q04322

TPPTLPP

6.50

-4.79

-3.58

PPLPPRA

6.67

-4.99

-3.78

SPPLPPR

6.89

-5.10

-3.89
P39940

WDDPRLP

7.63

-4.81

-3.60

DDPRLPS

7.84

-4.45

-3.24

DPRLPSS

8.46

-4.33

-3.12
P53901

MRPIPPL

5.12

-5.75

-4.54

LPPIPTR

5.13

-5.90

-4.69

RPIPPLP

5.27

-5.18

-3.97
P38990

SPIRPVL

5.55

-5.31

-4.10

LPKIPNS

6.33

-5.82

-4.61

SPAKNPN

6.42

-3.45

-2.24
P25693

PIPTIKP

7.74

-6.02

-4.81
P25333

TPAPTPT

7.90

-1.29

-0.08

YPEGAPT

8.48

-5.63

-4.42

ITPAPTP

9.28

-3.01

-1.80
P25558

SPVKKPM

5.70

-5.67

-4.46

HPKSPVK

6.46

-3.44

-2.23

NPSQPVT

6.57

-3.66

-2.45
P37370

RPHMPSV

3.58

-7.24

-6.03

APPIPGM

4.15

-5.61

-4.40

MPKPRPF

4.61

-7.25

-6.04
Q08446

SPISPLK

7.11

-3.61

-2.40

SHSPISP

8.86

-3.34

-2.13

HSPISPL

9.44

-2.63

-1.42
Q02209

PESKPNV

8.42

-3.97

-2.76

GPESKPN

8.83

-3.14

-1.93

 


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