ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-26.PDB
Scoring matrix: PIN3_1ZX6-26_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.55
Foldx random average score for Saccharomyces cerevisiae: 14.104

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2757445
Proteins after random average filtering: 6104
 Total fragments: 1052803
Proteins after disorder filtering: 3824
 Total fragments: 69002
Proteins after pattern filtering: 1969
 Total fragments: 14789
Proteins after MINT filtering: 25
 Total fragments: 495


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.55

-1.95

0.00

Best peptides

DRRPKMHPY

0.00

-11.01

-9.06

         
Interactors      
Q06604

EEKPLLPTR

6.78

-9.82

-7.87

SSPPPLPTR

7.20

-9.81

-7.86

EKGPRMPSR

7.21

-9.86

-7.91

P24583

PPQPRKHDK

9.69

-8.42

-6.47

NAPLPPQPR

9.78

-6.64

-4.69

APLPPQPRK

9.78

-6.36

-4.41

P38260

GGGPDDPTL

13.65

-4.97

-3.02

GGPDDPTLM

13.78

-2.21

-0.26

Q04322

STPPTLPPR

6.93

-10.52

-8.57

TPPTLPPRR

8.70

-8.13

-6.18

TSPPLPPRA

10.39

-6.81

-4.86

P19812

EPRPRRIPP

8.46

-8.27

-6.32

PRPRRIPPT

10.00

-6.54

-4.59

RPRRIPPTD

10.33

-5.20

-3.25

P15891

AAPPPPPRR

7.73

-10.04

-8.09

SAAPPPPPR

8.13

-8.75

-6.80

AAQPPLPSR

9.60

-10.00

-8.05

Q12344

STSPKLPPR

8.31

-9.29

-7.34

TSSPPLPPR

8.81

-9.26

-7.31

SSPPLPPRQ

9.66

-6.81

-4.86

P39521

VQTPHVPDR

9.79

-8.20

-6.25

PDRPPSQLS

10.07

-3.15

-1.20

HVPDRPPSQ

11.29

-4.83

-2.88

P40325

QSQPPRPPR

7.72

-7.95

-6.00

SSQPRPPPR

7.72

-9.35

-7.40

PPRPPRPAA

8.02

-6.67

-4.72

Q08601

YNRPVYPPP

8.79

-7.58

-5.63

YQRPMAPPP

8.87

-6.88

-4.93

APPPGPPPM

9.54

-7.27

-5.32

Q12532

PFKPYINGG

9.70

-6.41

-4.46

Q12168

RGPPPLPPR

6.79

-9.90

-7.95

DDPYFPQFR

8.89

-6.57

-4.62

DPYFPQFRS

10.28

-4.35

-2.40

Q12412

RPPQPPPAY

8.30

-6.96

-5.01

PQPPPAYDP

10.66

-6.03

-4.08

YDPNHRPPS

11.19

-7.18

-5.23

Q08412

DVPPQLPTR

7.33

-9.95

-8.00

IELPTQPVR

8.62

-8.99

-7.04

DIELPTQPV

11.99

-1.27

0.68

P53118

ENPHDLPSH

11.29

-5.76

-3.81

PHDLPSHLG

13.00

-5.53

-3.58

P38216

YSRPSNPPP

9.21

-7.22

-5.27

SRPSNPPPS

11.09

-5.69

-3.74

QYSRPSNPP

13.76

-3.91

-1.96

P53933

RRRPPPPPI

6.72

-6.94

-4.99

VAPPPLPNR

8.34

-9.82

-7.87

RTRRRPPPP

8.40

-7.40

-5.45

Q12446

PAPPPPPRR

7.66

-9.79

-7.84

NNRPVPPPP

8.33

-7.63

-5.68

APPPPPHRH

8.33

-7.64

-5.69

P38266

QPPPKPFRR

6.04

-9.19

-7.24

PPKPFRHGL

7.46

-8.66

-6.71

VEPPPPPSR

7.47

-9.25

-7.30

P40483

ASKPSVPPR

6.62

-10.01

-8.06

PSVPPRNYF

9.62

-7.24

-5.29

SKPSVPPRN

11.14

-5.84

-3.89

P07244

SEMPGMYPP

7.06

-8.44

-6.49

PGMYPPGHY

12.62

-4.90

-2.95

EMPGMYPPG

12.77

-6.17

-4.22

P40563

RAPPPVPKK

8.41

-7.15

-5.20

EVTPKVPER

9.42

-9.18

-7.23

KRRAPPPVP

9.87

-5.38

-3.43

Q07533

VKSDPHFPY

8.16

-4.80

-2.85

SSMPNSPKK

8.60

-5.73

-3.78

PKSPKAYPK

9.74

-6.07

-4.12

P53901

PPLPPIPTR

7.73

-9.10

-7.15

AMRPIPPLP

9.13

-6.07

-4.12

MAMRPIPPL

9.21

-6.80

-4.85

Q12489

YSRPSAPPP

8.81

-7.18

-5.23

RPSAPPPGY

10.23

-6.30

-4.35

SRPSAPPPG

11.07

-5.56

-3.61

 


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