ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-23.PDB
Scoring matrix: PIN3_1ZX6-23_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.06
Foldx random average score for Saccharomyces cerevisiae: 12.563

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2769653
Proteins after random average filtering: 6104
 Total fragments: 1728166
Proteins after disorder filtering: 4249
 Total fragments: 145276
Proteins after pattern filtering: 1948
 Total fragments: 8623
Proteins after MINT filtering: 25
 Total fragments: 201


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.06

1.64

0.00

Best peptides

RELGRMR

0.00

-3.31

-4.95

         
Interactors      
Q06604

GPRMPSR

4.23

-1.80

-3.44

KPLLPTR

5.40

-3.40

-5.04

LPTRPNK

7.04

-1.10

-2.74

P24583

LPPQPRK

7.45

-0.41

-2.05

NAPLPPQ

9.40

-0.75

-2.39

P38260

GGPDDPT

10.72

2.06

0.42

GPDDPTL

12.47

1.96

0.32

Q04322

APLDRPQ

7.35

0.65

-0.99

SPPLPPR

7.57

-1.31

-2.95

PPTLPPR

8.11

-2.13

-3.77

Q12168

PPPLPPR

7.08

-2.30

-3.94

VPNRPGG

7.47

-0.53

-2.17

PVPKPNI

9.88

-0.62

-2.26

P15891

PEKKPKE

4.67

-2.25

-3.89

PSKSPAP

7.07

-2.36

-4.00

TPEKKPK

7.09

0.17

-1.47

Q12344

SPKLPPR

6.84

-2.35

-3.99

TSPKLPP

6.95

0.01

-1.63

SPPLPPR

7.57

-1.31

-2.95

P39521

AQPKPKP

6.61

-0.04

-1.68

PKPKPAQ

7.18

-1.07

-2.71

VPDRPPS

8.40

0.52

-1.12

P40325

VQPGDPR

4.80

-0.65

-2.29

QPPRPPR

4.96

-0.89

-2.53

RPPRPAA

6.07

-1.91

-3.55

Q08601

PPPGPPP

4.56

-2.04

-3.68

RPMAPPP

4.63

-4.05

-5.69

QRPMAPP

5.65

-1.02

-2.66

P19812

RPRRIPP

3.78

-2.70

-4.34

PRPRRIP

6.61

-1.55

-3.19

NSPEASP

7.93

0.34

-1.30

Q12412

RPPQPPP

6.26

-1.12

-2.76

PPPAYDP

8.12

-1.87

-3.51

PNHRPPS

8.43

-0.91

-2.55

Q08412

WQPLPPE

7.43

-2.49

-4.13

LPPEPLD

7.56

0.08

-1.56

LPTQPVR

8.22

-0.65

-2.29

P53118

NPHDLPS

10.45

1.77

0.13

PHDLPSH

11.18

-1.35

-2.99

P38216

SRPSNPP

8.11

-0.35

-1.99

RPSNPPP

9.83

0.11

-1.53

P53933

LPMELPH

6.59

-1.32

-2.96

DLPMELP

7.06

-0.60

-2.24

SYPGNPT

7.17

-0.59

-2.23

Q12446

PRRGPAP

3.90

-3.12

-4.76

PPRRGPA

6.05

-2.23

-3.87

PPPRRGP

6.11

-1.96

-3.60

P38266

PPPKPFR

4.65

-0.93

-2.57

PPLKPGQ

5.23

-2.70

-4.34

KDPKSFP

5.50

-1.57

-3.21

P40483

SKPSVPP

8.04

-0.25

-1.89

PASKPSV

8.28

-0.64

-2.28

DAPASKP

9.11

-1.06

-2.70

P07244

MPGMYPP

5.07

-1.20

-2.84

EMPGMYP

5.16

-1.16

-2.80

P40563

VNPGQLP

6.32

-0.94

-2.58

QPQGPSD

6.45

-1.47

-3.11

PSERPKR

6.88

-0.88

-2.52

Q07533

MPNSPKK

5.43

-1.45

-3.09

KSPKAYP

5.78

-1.65

-3.29

SSPKSPK

6.90

-0.38

-2.02

P53901

NSPKLPP

7.04

-0.94

-2.58

IPPLPTE

7.58

0.08

-1.56

SPNSHPH

8.70

-0.31

-1.95

P37254

PGPGNPN

6.66

-1.11

-2.75

Q12489

RPSAPPP

7.07

-1.92

-3.56

SRPSAPP

7.95

-0.57

-2.21

 


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