ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-14.PDB
Scoring matrix: PIN3_1ZX6-14_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.53
Foldx random average score for Saccharomyces cerevisiae: 11.792

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2757445
Proteins after random average filtering: 6104
 Total fragments: 1223356
Proteins after disorder filtering: 3637
 Total fragments: 42038
Proteins after pattern filtering: 1581
 Total fragments: 5254
Proteins after MINT filtering: 23
 Total fragments: 164


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.53

-0.11

0.00

Best peptides

RWPMIRRQR

0.00

-6.96

-6.85

         
Interactors      
Q06604

LLPTRPNKA

8.86

-2.29

-2.18

TPPSPPAKR

8.88

-3.60

-3.49

GPRMPSRGR

9.08

-4.49

-4.38

P24583

LPPQPRKHD

7.77

-6.34

-6.23

PPQPRKHDK

9.23

-2.89

-2.78

Q04322

TPPTLPPRR

7.26

-2.84

-2.73

QAPLDRPQL

9.27

-5.60

-5.49

STPPTLPPR

11.41

-2.53

-2.42

P19812

HSPIFRPGN

8.54

-4.03

-3.92

RPRRIPPTD

9.54

-4.74

-4.63

PIFRPGNIF

10.62

-3.08

-2.97

P15891

PPLPSRNVA

9.96

-5.20

-5.09

ATPEKKPKE

9.96

-1.68

-1.57

PPPPPRRAT

10.57

-6.60

-6.49

Q12344

SPPLPPRQN

10.64

-4.10

-3.99

PKLPPRGKQ

11.08

-5.41

-5.30

PPLPPRQNV

11.45

-5.69

-5.58

P39521

VPDRPPSQL

9.41

-4.68

-4.57

AQPKPKPAQ

10.95

-0.97

-0.86

VQTPHVPDR

11.76

-0.51

-0.40

P40325

RPPRPAANL

8.45

-3.91

-3.80

LPWTYPPRF

8.73

-4.24

-4.13

RPHQRPSTM

9.02

-5.96

-5.85

Q08601

RPMAPPPNQ

9.96

-3.22

-3.11

QRPMAPPPN

11.60

-3.72

-3.61

Q12168

DDPYFPQFR

9.58

-1.80

-1.69

NDDPYFPQF

9.75

-1.54

-1.43

QHPVPKPNI

10.75

-2.92

-2.81

Q12412

YDPNHRPPS

7.26

-5.23

-5.12

PPAYDPNHR

9.46

-4.23

-4.12

RPPQPPPAY

10.03

-3.80

-3.69

Q08412

ELPTQPVRK

9.86

-3.00

-2.89

PQLPTRTKS

10.36

-3.37

-3.26

VPPQLPTRT

10.67

-2.79

-2.68

P53118

NPHDLPSHL

9.43

-3.35

-3.24

P38216

RPSNPPPSS

10.91

-2.88

-2.77

P53933

PPPIPSTQK

9.02

-3.78

-3.67

PPPLPNRQL

10.67

-6.07

-5.96

VAPPPLPNR

10.93

-2.76

-2.65

Q12446

RPLPQLPNR

7.63

-4.07

-3.96

PQLPNRNNR

9.04

-4.13

-4.02

PPPPHRHVT

9.36

-6.44

-6.33

P38266

KPPVVPKKK

7.09

-4.32

-4.21

PPPKPFRRS

7.74

-4.49

-4.38

PPPKPFRHT

8.49

-4.35

-4.24

P40483

KPSVPPRNY

9.49

-3.85

-3.74

PSVPPRNYF

11.02

-4.06

-3.95

SKPSVPPRN

11.65

-1.66

-1.55

P07244

MPGMYPPGH

9.94

-4.68

-4.57

P40563

PPPVPKKPS

9.12

-3.87

-3.76

PSERPKRRA

9.57

-2.49

-2.38

RAPPPVPKK

11.40

-2.08

-1.97

Q07533

KSPKAYPKL

9.17

-4.78

-4.67

SVSSPKSPK

10.82

-2.32

-2.21

MPNSPKKPV

10.94

-4.05

-3.94

P53901

PPIPTRDDM

8.90

-4.94

-4.83

NDPIILPPT

9.42

-2.27

-2.16

LPPIPTRDD

9.67

-2.28

-2.17

Q12489

RPSAPPPGY

11.59

-2.24

-2.13

 


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