ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-12.PDB
Scoring matrix: PIN3_1ZX6-12_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.0
Foldx random average score for Saccharomyces cerevisiae: 12.001

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2763549
Proteins after random average filtering: 6104
 Total fragments: 1170687
Proteins after disorder filtering: 3876
 Total fragments: 65155
Proteins after pattern filtering: 1807
 Total fragments: 9374
Proteins after MINT filtering: 23
 Total fragments: 340


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.00

-0.36

0.00

Best peptides

WRRRRRRK

0.00

-6.02

-5.66

         
Interactors      
Q06604

PSPPAKRI

7.87

-3.32

-2.96

KGPRMPSR

8.22

-3.72

-3.36

PRMPSRGR

8.97

-6.83

-6.47

P24583

PLPPQPRK

9.13

-1.97

-1.61

LPPQPRKH

9.54

-5.76

-5.40

RANAPLPP

10.66

-3.89

-3.53

Q04322

QAPLDRPQ

8.71

-5.96

-5.60

SPPLPPRA

8.78

-3.08

-2.72

PPTLPPRR

9.67

-2.18

-1.82

P19812

PRPRRIPP

5.34

-4.24

-3.88

RPRRIPPT

7.64

-4.44

-4.08

PIFRPGNI

8.91

-3.04

-2.68

P15891

PPPPPRRA

8.28

-5.80

-5.44

ATPEKKPK

8.93

-3.10

-2.74

PEKKPKEN

9.13

-3.48

-3.12

Q12344

SPPLPPRQ

8.74

-3.30

-2.94

SPKLPPRG

8.89

-3.69

-3.33

TSPKLPPR

9.04

-2.60

-2.24

P39521

AQPKPKPA

8.10

-3.83

-3.47

PKPKPAQD

10.18

-1.86

-1.50

VPDRPPSQ

10.39

-1.71

-1.35

P40325

QPPRPPRP

5.93

-3.33

-2.97

SQPRPPPR

6.93

-4.28

-3.92

QSRPHQRP

7.18

-2.98

-2.62

Q08601

GYQRPMAP

7.46

-4.49

-4.13

AYNRPVYP

8.70

-2.66

-2.30

QRPMAPPP

9.46

-3.50

-3.14

Q12168

PYFPQFRS

7.63

-3.81

-3.45

DPYFPQFR

8.43

-3.77

-3.41

PPPLPPRA

8.82

-3.15

-2.79

Q12412

YDPNHRPP

7.93

-5.26

-4.90

PNHRPPSS

8.46

-3.09

-2.73

AYDPNHRP

10.71

-1.42

-1.06

Q08412

KKWQPLPP

8.79

-5.26

-4.90

KNSRPQQP

8.92

-2.47

-2.11

NSRPQQPE

9.75

-2.04

-1.68

P53118

ENPHDLPS

9.98

-3.48

-3.12

P38216

QYSRPSNP

10.36

-1.42

-1.06

SRPSNPPP

10.65

-2.03

-1.67

YSRPSNPP

11.02

-2.09

-1.73

P53933

TRRRPPPP

4.86

-3.88

-3.52

RRRPPPPP

8.65

-2.93

-2.57

DLPMELPH

9.48

-4.23

-3.87

Q12446

PPRRGPAP

8.25

-2.89

-2.53

PPPPPRRG

8.31

-5.93

-5.57

NRPLPQLP

8.47

-3.80

-3.44

P38266

PPPKPFRR

6.52

-4.62

-4.26

PPPKPFRH

6.89

-4.15

-3.79

TPPRPPPS

8.20

-3.49

-3.13

P40483

DAPASKPS

9.93

-2.99

-2.63

SKPSVPPR

10.68

-1.82

-1.46

ASKPSVPP

11.46

-3.09

-2.73

P07244

EMPGMYPP

10.69

-2.77

-2.41

SEMPGMYP

10.89

-4.53

-4.17

PGMYPPGH

11.45

-3.80

-3.44

P40563

PSERPKRR

3.74

-4.85

-4.49

GTPNVPTR

10.31

-1.40

-1.04

VNPGQLPP

10.33

-3.45

-3.09

Q07533

KSPKAYPK

8.32

-2.76

-2.40

SMPNSPKK

8.94

-1.87

-1.51

SMNNPLPP

9.14

-3.41

-3.05

P53901

MAMRPIPP

6.82

-4.87

-4.51

SSPNSHPH

9.33

-2.60

-2.24

NSPKLPPL

9.49

-2.70

-2.34

Q12489

SYSRPSAP

10.12

-1.38

-1.02

SRPSAPPP

10.48

-1.83

-1.47

YSRPSAPP

10.91

-2.01

-1.65

 


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