ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-11.PDB
Scoring matrix: PIN3_1ZX6-11_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.02
Foldx random average score for Saccharomyces cerevisiae: 13.636

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2769653
Proteins after random average filtering: 6104
 Total fragments: 1085368
Proteins after disorder filtering: 4091
 Total fragments: 91634
Proteins after pattern filtering: 1955
 Total fragments: 10913
Proteins after MINT filtering: 23
 Total fragments: 359


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

16.02

1.84

0.00

Best peptides

FRPRGRF

0.00

-6.52

-8.36

         
Interactors      
Q06604

LPTRPNK

9.30

-4.55

-6.39

KGPRMPS

10.03

-4.21

-6.05

PRMPSRG

10.26

-2.87

-4.71

P24583

LPPQPRK

9.40

-4.38

-6.22

APLPPQP

11.80

-2.46

-4.30

PPQPRKH

13.36

-3.90

-5.74

Q04322

PLDRPQL

10.24

-3.35

-5.19

PTLPPRR

10.25

-1.93

-3.77

PPLPPRA

11.23

-3.38

-5.22

Q12168

VPNRPGG

9.89

-3.22

-5.06

PPVPNRP

9.92

-4.34

-6.18

PPPVPNR

10.07

-3.62

-5.46

P15891

PPPPPRR

8.82

-4.01

-5.85

PPPPRRA

10.80

-4.32

-6.16

FTPSKSP

11.09

-2.55

-4.39

Q12344

PPLPPRQ

11.31

-3.23

-5.07

PKLPPRG

11.85

-2.75

-4.59

SPPLPPR

12.33

-4.02

-5.86

P39521

VPDRPPS

10.10

-3.41

-5.25

HVPDRPP

11.70

-1.61

-3.45

TPHVPDR

11.97

-2.92

-4.76

P40325

PRPPPRP

7.73

-3.15

-4.99

QPPRPPR

7.94

-5.23

-7.07

SQPRPPP

9.10

-3.29

-5.13

Q08601

NRPVYPP

7.95

-1.57

-3.41

QRPMAPP

9.42

-3.77

-5.61

APPPGPP

10.17

-3.50

-5.34

P19812

HSPIFRP

6.82

-2.80

-4.64

PRPRRIP

6.95

-5.32

-7.16

PRRIPPT

9.68

-3.19

-5.03

Q12412

YDPNHRP

5.55

-3.55

-5.39

RPPQPPP

9.57

-5.33

-7.17

DPNHRPP

10.96

-2.70

-4.54

Q08412

LPTQPVR

11.47

-7.53

-9.37

SRPQQPE

12.08

-1.12

-2.96

WQPLPPE

12.38

-2.02

-3.86

P38216

RPSNPPP

10.27

-3.59

-5.43

SRPSNPP

10.66

-2.47

-4.31

YSRPSNP

10.71

-2.02

-3.86

P53933

RRPPPPP

9.04

-3.98

-5.82

RRRPPPP

9.24

-3.64

-5.48

RPPPPPI

10.65

-3.64

-5.48

Q12446

PPPRRGP

7.67

-5.31

-7.15

NRPVPPP

8.40

-3.88

-5.72

PPRRGPA

8.58

-5.32

-7.16

P38266

PPKPFRR

7.86

-4.10

-5.94

TPPRPPP

8.15

-3.77

-5.61

PPKPFRH

8.97

-3.14

-4.98

P40483

KPSVPPR

9.37

-6.72

-8.56

PSVPPRN

12.28

-1.20

-3.04

DAPASKP

12.30

-1.75

-3.59

P07244

MPGMYPP

9.57

-3.96

-5.80

EMPGMYP

13.43

-2.80

-4.64

P40563

PSERPKR

9.36

-2.85

-4.69

RAPPPVP

11.62

-1.90

-3.74

TPNVPTR

11.88

-2.90

-4.74

Q07533

IPPVPSR

9.73

-3.94

-5.78

PPVPSRY

10.33

-2.44

-4.28

KSDPHFP

10.53

-1.56

-3.40

P53901

MRPIPPL

9.42

-3.69

-5.53

LPPIPTR

10.24

-4.93

-6.77

DPIILPP

11.41

-4.20

-6.04

P37254

GPGPGNP

10.95

-2.33

-4.17

Q12489

SRPSAPP

10.81

-2.36

-4.20

RPSAPPP

11.14

-4.07

-5.91

YSRPSAP

11.70

-1.75

-3.59

 


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