ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-7.PDB
Scoring matrix: PIN3_1YNZ-7_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.24
Foldx random average score for Saccharomyces cerevisiae: 9.699

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2763549
Proteins after random average filtering: 6104
 Total fragments: 1422220
Proteins after disorder filtering: 4130
 Total fragments: 100233
Proteins after pattern filtering: 2008
 Total fragments: 14866
Proteins after MINT filtering: 25
 Total fragments: 474


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

11.24

1.41

0.00

Best peptides

FHPRGSRH

0.00

-3.53

-4.94

         
Interactors      
Q06604

KPLLPTRP

4.77

-4.98

-6.39

PPPLPTRR

4.84

-4.72

-6.13

FEKGPRMP

5.66

-3.29

-4.70

P24583

PLPPQPRK

7.17

-3.37

-4.78

LPPQPRKH

7.68

-3.98

-5.39

NAPLPPQP

7.80

-3.32

-4.73

P38260

GPDDPTLM

7.76

-3.06

-4.47

Q04322

PPTLPPRR

5.51

-4.83

-6.24

SPPLPPRA

5.82

-4.09

-5.50

PTLPPRRI

7.28

-3.86

-5.27

Q12168

PPPLPPRA

5.27

-4.85

-6.26

QHPVPKPN

5.37

-2.47

-3.88

DPYFPQFR

6.17

-2.37

-3.78

P15891

QPPLPSRN

4.32

-4.36

-5.77

APPPPPRR

5.87

-4.35

-5.76

PPPPPRRA

6.11

-4.53

-5.94

Q12344

SPPLPPRQ

5.75

-4.35

-5.76

SPKLPPRG

6.12

-3.71

-5.12

PPLPPRQN

7.68

-2.87

-4.28

P39521

VPDRPPSQ

6.71

-2.75

-4.16

PKPKPAQD

7.05

-2.94

-4.35

TPHVPDRP

7.34

-4.04

-5.45

P40325

QPPRPPRP

4.55

-4.85

-6.26

PHQRPSTM

5.94

-2.41

-3.82

QPRPPPRP

5.94

-4.61

-6.02

Q08601

PPGPPPMA

6.91

-3.85

-5.26

QRPMAPPP

7.18

-2.72

-4.13

RPMAPPPN

7.43

-3.16

-4.57

P19812

PEASPSLA

6.15

-2.02

-3.43

PRRIPPTD

7.35

-2.71

-4.12

PQNPPPIL

7.55

-2.81

-4.22

Q12412

RPPQPPPA

6.60

-2.28

-3.69

PNHRPPSS

7.80

-2.28

-3.69

PPQPPPAY

8.50

-2.53

-3.94

Q08412

PPQLPTRT

5.99

-4.42

-5.83

WQPLPPEP

6.33

-3.36

-4.77

KNSRPQQP

6.48

-3.39

-4.80

P53118

PHDLPSHL

5.52

-3.21

-4.62

VENPHDLP

9.28

-2.44

-3.85

NPHDLPSH

9.59

-1.12

-2.53

P38216

RPSNPPPS

6.72

-3.02

-4.43

QYSRPSNP

7.07

-2.88

-4.29

YSRPSNPP

7.86

-1.80

-3.21

P53933

PPPLPNRQ

5.67

-4.45

-5.86

RPPPPPIP

5.96

-3.51

-4.92

RRPPPPPI

6.25

-3.40

-4.81

Q12446

KHSLPPLP

3.64

-3.82

-5.23

VPPPPPMR

5.18

-4.88

-6.29

APPPPPRR

5.87

-4.35

-5.76

P38266

FPPPPLKP

4.89

-4.25

-5.66

VPILPPRN

4.99

-5.59

-7.00

FLPPPKPF

5.01

-3.86

-5.27

P40483

KPSVPPRN

4.69

-4.91

-6.32

KDAPASKP

7.21

-2.35

-3.76

PASKPSVP

7.92

-3.25

-4.66

P07244

MPGMYPPG

7.26

-3.45

-4.86

SEMPGMYP

8.23

-3.22

-4.63

PGMYPPGH

9.23

-2.24

-3.65

P40563

PSERPKRR

5.39

-3.47

-4.88

MVNPGQLP

6.33

-4.35

-5.76

RRAPPPVP

6.71

-3.83

-5.24

Q07533

IPPVPSRY

4.63

-5.22

-6.63

SMPNSPKK

6.27

-0.89

-2.30

MPNSPKKP

6.28

-2.95

-4.36

P53901

MRPIPPLP

4.10

-5.98

-7.39

QPPLPPIP

5.69

-4.31

-5.72

LPPIPTRD

6.30

-4.61

-6.02

P37254

GPGPGNPN

8.70

-1.26

-2.67

GPGNPNNG

9.48

-1.54

-2.95

VGPGPGNP

9.67

-1.51

-2.92

Q12489

RPSAPPPG

7.24

-2.24

-3.65

YSRPSAPP

7.72

-1.86

-3.27

SYSRPSAP

8.81

-2.03

-3.44

 


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