ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-21.PDB
Scoring matrix: PIN3_1YNZ-21_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 17.11
Foldx random average score for Saccharomyces cerevisiae: 14.664

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2751341
Proteins after random average filtering: 6104
 Total fragments: 1691293
Proteins after disorder filtering: 3806
 Total fragments: 62039
Proteins after pattern filtering: 1505
 Total fragments: 3920
Proteins after MINT filtering: 21
 Total fragments: 89


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

17.11

-1.25

0.00

Best peptides

ERFMRRPTMM

0.00

-3.09

-1.84

         
Interactors      
P39521

QPKPKPAQDN

12.72

-2.09

-0.84

HVPDRPPSQL

14.43

-4.16

-2.91

Q06604

EKGPRMPSRG

8.94

-5.11

-3.86

PLLPTRPNKA

9.54

-4.70

-3.45

PPLPTRRDHI

13.03

-2.76

-1.51

P53118

ENPHDLPSHL

11.98

-3.77

-2.52

P40325

SRPHQRPSTM

9.74

-3.53

-2.28

YVQPGDPRLG

10.24

-6.54

-5.29

PRPPRPAANL

11.84

-3.64

-2.39

P24583

PPQPRKHDKT

12.65

-3.94

-2.69

PLPPQPRKHD

14.03

-3.81

-2.56

P07244

MPGMYPPGHY

13.88

-3.64

-2.39

P53933

VSYPGNPTSR

9.39

-2.97

-1.72

PPPPIPSTQK

13.96

-3.54

-2.29

P40563

NSQPQGPSDT

13.66

-2.43

-1.18

NPGQLPPSLE

14.25

-3.34

-2.09

P53901

DPIILPPTFS

11.21

-5.24

-3.99

KLPPLPTTSN

12.05

-3.94

-2.69

PPIPTRDDMS

12.71

-3.82

-2.57

Q12532

PFKPYINGGD

13.77

-2.36

-1.11

P19812

RPRRIPPTDE

11.85

-3.26

-2.01

HSPIFRPGNI

12.43

-2.78

-1.53

NSPEASPSLA

13.20

-4.70

-3.45

Q04322

TPPTLPPRRI

14.10

-5.06

-3.81

Q12168

PNRPGGTTNR

8.46

-3.43

-2.18

NDDPYFPQFR

10.91

-4.87

-3.62

PPVPNRPGGT

13.98

-2.11

-0.86

P15891

DEPEGEPDVK

12.85

-3.20

-1.95

ATPEKKPKEN

13.19

-3.71

-2.46

PPLPSRNVAS

13.52

-3.59

-2.34

Q12446

RPLPQLPNRN

9.67

-3.85

-2.60

NNAPSQPQSN

11.77

-2.21

-0.96

PPPPMRTTTE

11.82

-3.80

-2.55

P37254

GPGPGNPNNG

13.45

-2.78

-1.53

P38260

GGGPDDPTLM

9.72

-3.85

-2.60

Q08412

IELPTQPVRK

9.34

-4.41

-3.16

DVPPQLPTRT

10.43

-4.46

-3.21

PQLPTRTKSG

12.35

-2.31

-1.06

Q12344

PLPPRQNVAT

13.06

-4.60

-3.35

SSPPLPPRQN

13.42

-4.58

-3.33

Q07533

PPLPDLDNMR

10.99

-4.82

-3.57

VSSPKSPKAY

12.64

-3.28

-2.03

P38266

PLKPGQKTYT

7.88

-5.06

-3.81

KKPPVVPKKK

9.92

-5.00

-3.75

PPKPFRHTET

10.24

-3.84

-2.59

 


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