ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-14.PDB
Scoring matrix: PIN3_1YNZ-14_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.18
Foldx random average score for Saccharomyces cerevisiae: 13.070

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2757445
Proteins after random average filtering: 6104
 Total fragments: 1263833
Proteins after disorder filtering: 3646
 Total fragments: 42883
Proteins after pattern filtering: 1481
 Total fragments: 4410
Proteins after MINT filtering: 21
 Total fragments: 130


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.18

-0.42

0.00

Best peptides

FFFMTKKRR

0.00

-3.24

-2.82

         
Interactors      
P39521

AQPKPKPAQ

10.65

-2.25

-1.83

VPDRPPSQL

12.60

-3.69

-3.27

HVPDRPPSQ

12.70

-4.05

-3.63

Q06604

LLPTRPNKA

10.09

-5.46

-5.04

SPPPLPTRR

10.46

-4.63

-4.21

NIPSSKPAG

10.58

-2.94

-2.52

P53118

NPHDLPSHL

12.53

-4.06

-3.64

P40325

SLPWTYPPR

9.71

-5.86

-5.44

LPWTYPPRF

10.11

-4.82

-4.40

RPHQRPSTM

10.63

-5.99

-5.57

P24583

PPQPRKHDK

10.89

-3.04

-2.62

LPPQPRKHD

11.07

-6.77

-6.35

APLPPQPRK

12.49

-4.17

-3.75

P07244

MPGMYPPGH

12.58

-5.27

-4.85

P53933

APPPLPNRQ

11.83

-4.98

-4.56

PPPIPSTQK

12.21

-4.70

-4.28

VAPPPLPNR

12.62

-4.58

-4.16

Q08601

RPMAPPPNQ

12.53

-4.27

-3.85

P53901

PPIPTRDDM

11.45

-5.69

-5.27

DPIILPPTF

11.71

-3.91

-3.49

LPPIPTRDD

12.72

-4.59

-4.17

Q12168

DPYFPQFRS

12.16

-2.96

-2.54

GPPPLPPRA

12.73

-3.05

-2.63

DDPYFPQFR

12.94

-3.80

-3.38

Q04322

TPPTLPPRR

8.05

-4.81

-4.39

STPPTLPPR

11.75

-4.58

-4.16

TPSKSPTSA

12.06

-2.63

-2.21

Q07533

KSPKAYPKL

9.25

-5.41

-4.99

MPNSPKKPV

11.37

-3.40

-2.98

SVSSPKSPK

11.88

-2.88

-2.46

P15891

ATPEKKPKE

9.59

-3.37

-2.95

RATPEKKPK

10.74

-3.14

-2.72

SFTPSKSPA

11.25

-1.85

-1.43

P40563

PSERPKRRA

8.73

-3.55

-3.13

PPPVPKKPS

10.73

-4.46

-4.04

SEVTPKVPE

11.65

-3.12

-2.70

Q12446

RPLPQLPNR

10.38

-4.45

-4.03

LPPASPEVR

10.38

-4.54

-4.12

PLPQLPNRN

11.40

-3.41

-2.99

P19812

RPRRIPPTD

10.55

-4.58

-4.16

HSPIFRPGN

10.84

-4.05

-3.63

PIFRPGNIF

12.69

-3.60

-3.18

Q08412

ELPTQPVRK

9.74

-4.33

-3.91

IELPTQPVR

10.91

-1.78

-1.36

LPTQPVRKN

12.17

-4.98

-4.56

Q12344

TSPKLPPRG

12.25

-1.98

-1.56

STSPKLPPR

12.99

-2.71

-2.29

PKLPPRGKQ

13.03

-7.48

-7.06

Q12412

PPAYDPNHR

11.97

-4.11

-3.69

RPPQPPPAY

12.60

-4.37

-3.95

P38266

KPPVVPKKK

7.68

-6.02

-5.60

FLPPPKPFR

7.83

-5.93

-5.51

IMPPPKPFR

8.07

-4.41

-3.99

P40483

KPSVPPRNY

11.76

-5.17

-4.75

SKPSVPPRN

11.90

-2.84

-2.42

DAPASKPSV

12.28

0.26

0.68

 


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