ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-8.PDB
Scoring matrix: PIN3_1CKB-8_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.67
Foldx random average score for Saccharomyces cerevisiae: 11.236

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2763549
Proteins after random average filtering: 6104
 Total fragments: 1446653
Proteins after disorder filtering: 4017
 Total fragments: 99045
Proteins after pattern filtering: 2013
 Total fragments: 16729
Proteins after MINT filtering: 25
 Total fragments: 529


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.67

-1.65

0.00

Best peptides

RMKFLPPF

0.00

-4.38

-2.73

         
Interactors      
Q06604

SPPPLPTR

3.30

-10.58

-8.93

EKPLLPTR

3.38

-9.99

-8.34

KGPRMPSR

4.86

-9.69

-8.04

P24583

ANAPLPPQ

6.95

-6.01

-4.36

APLPPQPR

7.85

-7.01

-5.36

LPPQPRKH

7.93

-5.78

-4.13

P38260

GGPDDPTL

7.78

-5.04

-3.39

Q04322

TPPTLPPR

3.20

-10.42

-8.77

TSPPLPPR

4.54

-9.33

-7.68

APLDRPQL

5.75

-5.62

-3.97

Q12168

GPPPLPPR

2.48

-10.44

-8.79

IPPPVPNR

4.70

-10.74

-9.09

DDPYFPQF

5.66

-5.89

-4.24

P15891

AQPPLPSR

3.72

-10.95

-9.30

APPPPPRR

5.29

-8.95

-7.30

PPPPRRAT

5.32

-6.15

-4.50

Q12344

SSPPLPPR

4.51

-9.18

-7.53

TSPKLPPR

4.92

-7.66

-6.01

PKLPPRGK

6.72

-5.58

-3.93

P39521

QPKPKPAQ

5.27

-4.64

-2.99

HVPDRPPS

6.70

-5.59

-3.94

QTPHVPDR

6.90

-8.44

-6.79

P40325

SQPPRPPR

4.57

-10.51

-8.86

PRPPRPAA

4.65

-5.98

-4.33

RPPPRPQQ

4.94

-7.90

-6.25

Q08601

PPPGPPPM

5.46

-6.82

-5.17

QRPMAPPP

6.15

-5.27

-3.62

NRPVYPPP

6.22

-6.56

-4.91

P19812

RPRRIPPT

4.54

-6.49

-4.84

EPRPRRIP

5.52

-3.03

-1.38

SPIFRPGN

7.02

-5.91

-4.26

Q12412

PPQPPPAY

6.14

-5.58

-3.93

DPNHRPPS

6.46

-4.01

-2.36

RPPQPPPA

7.06

-6.62

-4.97

Q08412

VPPQLPTR

3.94

-10.35

-8.70

KWQPLPPE

6.28

-4.73

-3.08

WQPLPPEP

7.38

-7.23

-5.58

P53118

NPHDLPSH

6.53

-5.91

-4.26

ENPHDLPS

9.17

-4.22

-2.57

VENPHDLP

10.86

-1.44

0.21

P38216

SRPSNPPP

6.37

-6.32

-4.67

RPSNPPPS

9.57

-4.13

-2.48

PSNPPPSS

9.80

-2.67

-1.02

P53933

APPPLPNR

2.89

-11.27

-9.62

PPPPIPST

4.20

-7.41

-5.76

RRPPPPPI

4.81

-6.22

-4.57

Q12446

APPPPPAF

3.84

-7.83

-6.18

IPPTLPST

4.28

-8.12

-6.47

FPFPIPEI

4.29

-6.61

-4.96

P38266

AVPILPPR

4.04

-8.74

-7.09

MPPPKPFR

4.39

-9.77

-8.12

QPPPKPFR

4.39

-8.18

-6.53

P40483

SKPSVPPR

4.58

-9.29

-7.64

APASKPSV

7.59

-3.97

-2.32

KPSVPPRN

9.25

-4.69

-3.04

P07244

EMPGMYPP

5.18

-6.25

-4.60

PGMYPPGH

9.12

-2.82

-1.17

SEMPGMYP

9.95

-3.47

-1.82

P40563

APPPVPKK

4.45

-8.26

-6.61

VTPKVPER

6.14

-6.58

-4.93

GTPNVPTR

7.04

-6.64

-4.99

Q07533

MNNPLPPL

4.85

-6.37

-4.72

SMPNSPKK

5.49

-6.38

-4.73

SAPNLPLA

5.90

-6.18

-4.53

P53901

AMRPIPPL

3.12

-6.91

-5.26

NQPPLPPI

3.97

-8.76

-7.11

NSPKLPPL

5.44

-5.67

-4.02

P37254

PGPGNPNN

9.66

-4.23

-2.58

Q12489

SRPSAPPP

6.29

-6.37

-4.72

PSAPPPGY

8.64

-3.28

-1.63

RPSAPPPG

9.58

-4.89

-3.24

 


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