ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-7.PDB
Scoring matrix: PIN3_1CKB-7_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 12.88
Foldx random average score for Saccharomyces cerevisiae: 10.270

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2763549
Proteins after random average filtering: 6104
 Total fragments: 1203353
Proteins after disorder filtering: 3862
 Total fragments: 58986
Proteins after pattern filtering: 1897
 Total fragments: 11927
Proteins after MINT filtering: 23
 Total fragments: 406


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

12.88

-2.85

0.00

Best peptides

WLPFPPWR

0.00

-4.32

-1.47

         
Interactors      
Q06604

PPPLPTRR

4.67

-6.98

-4.13

PPSPPAKR

6.18

-7.38

-4.53

EKPLLPTR

6.88

-6.86

-4.01

P24583

LPPQPRKH

6.80

-6.72

-3.87

PLPPQPRK

7.52

-5.19

-2.34

APLPPQPR

8.14

-5.34

-2.49

Q04322

PPTLPPRR

4.64

-7.41

-4.56

SPPLPPRA

5.74

-6.99

-4.14

TSPPLPPR

7.46

-4.71

-1.86

P19812

PRRIPPTD

6.25

-6.59

-3.74

PQNPPPIL

7.27

-6.65

-3.80

SPIFRPGN

8.18

-3.80

-0.95

P15891

QPPLPSRN

4.70

-6.92

-4.07

APPPPPRR

5.07

-6.65

-3.80

PPPPPRRA

6.79

-7.23

-4.38

Q12344

SPPLPPRQ

5.30

-6.30

-3.45

SPKLPPRG

5.82

-6.05

-3.20

TSPKLPPR

6.03

-4.68

-1.83

P39521

PKPKPAQD

6.69

-6.72

-3.87

TPHVPDRP

7.43

-5.28

-2.43

VPDRPPSQ

7.46

-5.29

-2.44

P40325

QPPRPPRP

6.23

-9.27

-6.42

PWTYPPRF

6.37

-6.70

-3.85

SQPRPPPR

6.55

-5.05

-2.20

Q08601

PPGPPPMA

6.96

-7.63

-4.78

PMAPPPNQ

7.50

-6.50

-3.65

RPMAPPPN

8.52

-5.69

-2.84

Q12168

DPYFPQFR

5.18

-7.60

-4.75

PPPLPPRA

5.60

-7.47

-4.62

PVPKPNID

6.31

-6.72

-3.87

Q12412

PQPPPAYD

7.09

-6.09

-3.24

RPPQPPPA

7.43

-6.33

-3.48

PPQPPPAY

8.58

-6.18

-3.33

Q08412

PPQLPTRT

6.90

-6.51

-3.66

VPPQLPTR

6.97

-5.86

-3.01

WQPLPPEP

7.35

-6.04

-3.19

P53118

PHDLPSHL

7.19

-7.06

-4.21

P38216

RPSNPPPS

9.16

-5.44

-2.59

QYSRPSNP

9.33

-4.42

-1.57

PSNPPPSS

9.41

-5.20

-2.35

P53933

PPPLPNRQ

5.87

-9.61

-6.76

PPPIPSTQ

6.73

-7.20

-4.35

RRPPPPPI

7.09

-5.84

-2.99

Q12446

VPPPPPMR

4.30

-7.35

-4.50

APPPPPRR

5.07

-6.65

-3.80

PPPPPHRH

5.61

-7.34

-4.49

P38266

PPPKPFRR

4.08

-7.41

-4.56

PPPKPFRH

4.27

-8.00

-5.15

VPILPPRN

4.97

-5.82

-2.97

P40483

KPSVPPRN

5.13

-6.99

-4.14

PASKPSVP

8.65

-6.40

-3.55

PSVPPRNY

8.94

-5.65

-2.80

P07244

PGMYPPGH

7.70

-6.08

-3.23

MPGMYPPG

8.77

-7.59

-4.74

P40563

PSERPKRR

5.70

-6.32

-3.47

TPKVPERP

7.00

-7.85

-5.00

PPPVPKKP

7.67

-7.35

-4.50

Q07533

IPPVPSRY

5.08

-8.17

-5.32

SDPHFPYG

7.06

-5.52

-2.67

NNPLPPLP

7.64

-7.09

-4.24

P53901

MRPIPPLP

5.06

-8.95

-6.10

QPPLPPIP

6.09

-7.80

-4.95

LPPIPTRD

6.88

-7.54

-4.69

Q12489

PSAPPPGY

8.98

-5.24

-2.39

RPSAPPPG

9.03

-5.75

-2.90

 


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