ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-26.PDB
Scoring matrix: PIN3_1CKB-26_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.97
Foldx random average score for Saccharomyces cerevisiae: 12.692

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2757445
Proteins after random average filtering: 6103
 Total fragments: 1096727
Proteins after disorder filtering: 3654
 Total fragments: 54426
Proteins after pattern filtering: 1923
 Total fragments: 14444
Proteins after MINT filtering: 25
 Total fragments: 487


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.97

-2.87

0.00

Best peptides

RRIPRLIPR

0.00

-4.56

-1.69

         
Interactors      
Q06604

SSPPPLPTR

1.86

-9.88

-7.01

EEKPLLPTR

2.18

-9.35

-6.48

SPPPLPTRR

5.03

-6.60

-3.73

P24583

NAPLPPQPR

7.03

-5.50

-2.63

PPQPRKHDK

7.23

-6.26

-3.39

APLPPQPRK

8.24

-8.04

-5.17

P38260

GGPDDPTLM

9.61

-4.33

-1.46

Q04322

STPPTLPPR

1.73

-10.11

-7.24

TPPTLPPRR

5.44

-6.23

-3.36

TSPPLPPRA

8.57

-8.47

-5.60

P19812

EPRPRRIPP

6.51

-9.04

-6.17

PRPRRIPPT

9.40

-7.93

-5.06

DAPQNPPPI

9.75

-5.88

-3.01

P15891

AAQPPLPSR

3.39

-8.68

-5.81

AAPPPPPRR

4.29

-8.14

-5.27

SAAPPPPPR

4.68

-6.93

-4.06

Q12344

TSSPPLPPR

2.97

-8.74

-5.87

STSPKLPPR

3.02

-9.03

-6.16

SSPPLPPRQ

7.86

-7.56

-4.69

P39521

VQTPHVPDR

5.82

-6.52

-3.65

AQPKPKPAQ

8.29

-6.73

-3.86

PHVPDRPPS

8.71

-6.69

-3.82

P40325

QSQPPRPPR

3.40

-9.30

-6.43

SSQPRPPPR

3.67

-7.74

-4.87

SLPWTYPPR

5.02

-6.23

-3.36

Q08601

APPPGPPPM

5.38

-8.39

-5.52

YNRPVYPPP

9.82

-6.93

-4.06

RPMAPPPNQ

10.01

-5.78

-2.91

Q12532

PFKPYINGG

12.59

-5.79

-2.92

Q12168

RGPPPLPPR

1.39

-10.18

-7.31

DDPYFPQFR

7.05

-5.43

-2.56

PPVPNRPGG

9.06

-7.38

-4.51

Q12412

RPPQPPPAY

8.90

-6.45

-3.58

PPAYDPNHR

9.10

-6.50

-3.63

YDPNHRPPS

9.63

-7.25

-4.38

Q08412

DVPPQLPTR

3.15

-9.74

-6.87

IELPTQPVR

6.67

-7.36

-4.49

KKWQPLPPE

8.45

-6.62

-3.75

P53118

ENPHDLPSH

6.51

-8.26

-5.39

P38216

YSRPSNPPP

10.25

-6.12

-3.25

SRPSNPPPS

10.47

-5.90

-3.03

RPSNPPPSS

12.51

-3.99

-1.12

P53933

VAPPPLPNR

2.78

-9.65

-6.78

RRRPPPPPI

7.19

-7.43

-4.56

SYPGNPTSR

8.05

-4.43

-1.56

Q12446

RPLPQLPNR

3.71

-8.95

-6.08

RPVPPPPPM

4.17

-7.54

-4.67

PAPPPPPRR

4.20

-8.52

-5.65

P38266

RAVPILPPR

1.81

-8.70

-5.83

IMPPPKPFR

3.60

-8.97

-6.10

FLPPPKPFR

3.92

-9.05

-6.18

P40483

ASKPSVPPR

4.53

-7.14

-4.27

PSVPPRNYF

9.29

-6.74

-3.87

SKPSVPPRN

10.92

-5.24

-2.37

P07244

SEMPGMYPP

9.99

-6.97

-4.10

MPGMYPPGH

11.16

-5.43

-2.56

EMPGMYPPG

11.37

-6.23

-3.36

P40563

EVTPKVPER

5.20

-6.61

-3.74

RAPPPVPKK

5.77

-9.26

-6.39

AGTPNVPTR

6.31

-6.50

-3.63

Q07533

SSMPNSPKK

7.29

-6.86

-3.99

NPLPPLPPL

7.45

-9.26

-6.39

KSPKAYPKL

8.12

-5.37

-2.50

P53901

PPLPPIPTR

6.23

-8.80

-5.93

RPIPPLPTE

7.12

-7.84

-4.97

YNQPPLPPI

7.14

-8.39

-5.52

Q12489

YSRPSAPPP

10.35

-6.77

-3.90

SRPSAPPPG

10.45

-6.76

-3.89

RPSAPPPGY

11.33

-4.58

-1.71

 


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