ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-23.PDB
Scoring matrix: PIN3_1CKB-23_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 10.48
Foldx random average score for Saccharomyces cerevisiae: 9.260

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2769653
Proteins after random average filtering: 6104
 Total fragments: 1489800
Proteins after disorder filtering: 4188
 Total fragments: 100132
Proteins after pattern filtering: 1977
 Total fragments: 13962
Proteins after MINT filtering: 25
 Total fragments: 460


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

10.48

-3.10

0.00

Best peptides

MPRPRRL

0.00

-5.46

-2.36

         
Interactors      
Q06604

GPRMPSR

5.01

-6.46

-3.36

SSPPPLP

5.14

-5.56

-2.46

PPLPTRR

5.22

-5.32

-2.22

P24583

LPPQPRK

4.57

-5.60

-2.50

NAPLPPQ

5.10

-5.94

-2.84

APLPPQP

5.74

-5.42

-2.32

P38260

PDDPTLM

8.10

-4.58

-1.48

GGGPDDP

8.60

-3.92

-0.82

Q04322

SPPLPPR

4.35

-4.96

-1.86

PTLPPRR

5.40

-5.25

-2.15

QAPLDRP

5.49

-4.71

-1.61

Q12168

RGPPPLP

4.71

-6.36

-3.26

HPVPKPN

5.57

-4.95

-1.85

QHPVPKP

5.58

-6.25

-3.15

P15891

APPPPPR

4.54

-4.90

-1.80

QPPLPSR

4.56

-4.80

-1.70

PPPPPRR

4.80

-4.97

-1.87

Q12344

SPKLPPR

4.18

-5.45

-2.35

SPPLPPR

4.35

-4.96

-1.86

TSSPPLP

4.38

-4.73

-1.63

P39521

TPHVPDR

4.72

-5.02

-1.92

PDRPPSQ

5.90

-6.65

-3.55

QPKPKPA

5.95

-4.04

-0.94

P40325

QPRPPPR

2.96

-7.32

-4.22

RPPPRPQ

3.45

-5.53

-2.43

NPSLPWT

4.51

-5.64

-2.54

Q08601

YNRPVYP

4.73

-4.95

-1.85

YQRPMAP

5.02

-4.66

-1.56

YAPPPGP

5.83

-4.29

-1.19

Q12532

PFKPYIN

7.98

-4.34

-1.24

P19812

RPRRIPP

5.06

-6.06

-2.96

PRPRRIP

7.16

-6.34

-3.24

PQNPPPI

7.23

-5.11

-2.01

Q12412

RPPQPPP

6.52

-4.94

-1.84

PQPPPAY

7.24

-4.77

-1.67

PPQPPPA

7.95

-4.42

-1.32

Q08412

WQPLPPE

5.06

-5.17

-2.07

QPLPPEP

5.09

-5.32

-2.22

NSRPQQP

5.39

-6.05

-2.95

P38216

YSRPSNP

5.33

-4.30

-1.20

RPSNPPP

6.61

-4.20

-1.10

SRPSNPP

8.61

-3.57

-0.47

P53933

RRRPPPP

3.50

-7.06

-3.96

RPPPPPI

4.23

-5.93

-2.83

RRPPPPP

4.51

-6.55

-3.45

Q12446

MSSPPPP

3.21

-5.36

-2.26

VPPPPPM

3.70

-5.32

-2.22

LPPLPNQ

4.14

-5.72

-2.62

P38266

MPPPKPF

3.57

-5.98

-2.88

VPILPPR

3.72

-7.46

-4.36

FPPPPLK

3.79

-4.91

-1.81

P40483

KPSVPPR

4.56

-6.11

-3.01

ASKPSVP

6.95

-4.69

-1.59

PSVPPRN

7.15

-6.00

-2.90

P07244

MPGMYPP

5.67

-6.46

-3.36

P40563

TPKVPER

4.69

-5.57

-2.47

APPPVPK

5.29

-4.93

-1.83

RAPPPVP

5.63

-5.74

-2.64

Q07533

LPPLPPL

3.17

-7.47

-4.37

LPPLPDL

3.64

-6.63

-3.53

NPLPPLP

4.25

-7.38

-4.28

P53901

RPIPPLP

3.76

-7.85

-4.75

LNSPKLP

4.03

-5.44

-2.34

SPKLPPL

4.09

-4.98

-1.88

P37254

GPGPGNP

7.99

-4.08

-0.98

Q12489

YSRPSAP

5.25

-3.63

-0.53

RPSAPPP

5.97

-5.14

-2.04

SRPSAPP

8.45

-4.15

-1.05

 


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