ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-21.PDB
Scoring matrix: PIN3_1CKB-21_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 15.55
Foldx random average score for Saccharomyces cerevisiae: 15.260

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2751341
Proteins after random average filtering: 6103
 Total fragments: 1636485
Proteins after disorder filtering: 3863
 Total fragments: 74602
Proteins after pattern filtering: 1550
 Total fragments: 4520
Proteins after MINT filtering: 22
 Total fragments: 108


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

15.55

-0.80

0.00

Best peptides

QRRMGDPKMW

0.00

-1.99

-1.19

         
Interactors      
Q06604

SPPPLPTRRD

8.94

-4.61

-3.81

EKGPRMPSRG

10.97

-4.87

-4.07

PLLPTRPNKA

12.91

-2.78

-1.98

P40325

SRPHQRPSTM

10.44

-2.88

-2.08

PRPPRPAANL

10.77

-3.39

-2.59

YVQPGDPRLG

10.81

-2.97

-2.17

P38260

GGGPDDPTLM

10.07

-4.27

-3.47

Q04322

TPPTLPPRRI

11.67

-3.44

-2.64

TSPPLPPRAD

12.15

-0.85

-0.05

TPSKSPTSAV

13.83

-0.89

-0.09

Q12168

NDDPYFPQFR

11.59

-3.24

-2.44

GPPPLPPRAN

12.12

-2.39

-1.59

PNRPGGTTNR

12.35

-3.08

-2.28

P15891

ATPEKKPKEN

11.83

-1.63

-0.83

DEPEGEPDVK

12.83

-0.75

0.05

TPSPAPAAKI

13.22

-2.63

-1.83

Q12344

TSPKLPPRGK

11.97

0.11

0.91

SSPPLPPRQN

12.00

-1.80

-1.00

PLPPRQNVAT

14.56

-3.61

-2.81

P39521

HVPDRPPSQL

12.78

-0.60

0.20

QPKPKPAQDN

13.73

-0.53

0.27

P24583

PPQPRKHDKT

11.92

-1.65

-0.85

PLPPQPRKHD

12.61

-3.39

-2.59

APLPPQPRKH

13.90

-3.80

-3.00

Q12532

PFKPYINGGD

14.60

-3.06

-2.26

P19812

SPIFRPGNIF

8.76

-4.08

-3.28

NSPEASPSLA

12.48

-2.86

-2.06

HSPIFRPGNI

14.48

-2.51

-1.71

Q12412

PPPAYDPNHR

11.59

-2.28

-1.48

DPNHRPPSSS

13.43

-1.60

-0.80

Q08412

IELPTQPVRK

9.72

-4.63

-3.83

VPPQLPTRTK

12.19

0.04

0.84

DVPPQLPTRT

12.95

-4.87

-4.07

P53118

ENPHDLPSHL

10.94

-2.56

-1.76

P53933

VSYPGNPTSR

11.11

-2.15

-1.35

APPPLPNRQL

11.15

-2.80

-2.00

PPPPIPSTQK

14.60

-2.35

-1.55

Q12446

RPLPQLPNRN

6.94

-4.04

-3.24

LPPASPEVRK

10.81

-5.01

-4.21

PPPPTAETFD

13.07

-2.83

-2.03

P38266

NIYPIEPSLD

9.29

-3.57

-2.77

KKPPVVPKKK

10.10

-3.94

-3.14

KVPPVVPKKN

10.80

-3.30

-2.50

P07244

MPGMYPPGHY

14.89

-3.92

-3.12

P40563

NPGQLPPSLE

12.48

-2.12

-1.32

NSQPQGPSDT

12.90

-2.02

-1.22

Q07533

PPLPDLDNMR

8.22

-5.39

-4.59

VSSPKSPKAY

11.84

-1.74

-0.94

KSDPHFPYGT

13.09

0.09

0.89

P53901

PPLPTTSNSN

12.01

-1.20

-0.40

PPIPTRDDMS

12.24

-2.30

-1.50

PLPPIPTRDD

13.85

-1.67

-0.87

P37254

GPGPGNPNNG

12.43

-1.60

-0.80

PGNPNNGAQD

12.47

-1.73

-0.93

 


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