ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-19.PDB
Scoring matrix: PIN3_1CKB-19_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.5
Foldx random average score for Saccharomyces cerevisiae: 15.855

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2757445
Proteins after random average filtering: 6104
 Total fragments: 1164505
Proteins after disorder filtering: 3783
 Total fragments: 50706
Proteins after pattern filtering: 1710
 Total fragments: 6668
Proteins after MINT filtering: 23
 Total fragments: 197


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.50

-0.83

0.00

Best peptides

IRSRWGRHM

0.00

-4.12

-3.29

         
Interactors      
Q06604

PPSPPAKRI

9.77

-9.58

-8.75

GPRMPSRGR

11.32

-8.99

-8.16

LPTRPNKAE

12.21

-7.12

-6.29

P24583

APLPPQPRK

13.37

-8.41

-7.58

LPPQPRKHD

13.51

-9.45

-8.62

PPQPRKHDK

14.85

-7.33

-6.50

Q04322

DQAPLDRPQ

13.40

-5.26

-4.43

GNATPSKSP

15.15

-5.71

-4.88

Q12168

VPNRPGGTT

11.06

-5.83

-5.00

DPYFPQFRS

11.75

-5.86

-5.03

PPLPPRANV

12.35

-10.00

-9.17

P15891

RRATPEKKP

11.57

-7.01

-6.18

ISPKPFSKP

12.60

-7.66

-6.83

QPPLPSRNV

12.69

-9.00

-8.17

Q12344

PPLPPRQNV

12.49

-10.07

-9.24

PKLPPRGKQ

12.56

-7.84

-7.01

P39521

AQPKPKPAQ

12.72

-5.90

-5.07

PKPKPAQDN

13.82

-6.21

-5.38

TPHVPDRPP

13.93

-9.51

-8.68

P40325

RPPRPAANL

8.64

-9.04

-8.21

HQSRPHQRP

11.67

-7.69

-6.86

PRPPPRPQQ

12.77

-8.48

-7.65

Q08601

GYQRPMAPP

14.74

-6.31

-5.48

PGPPPMAYN

15.47

-7.64

-6.81

AYNRPVYPP

15.54

-6.75

-5.92

P19812

PIFRPGNIF

10.78

-8.07

-7.24

DHSPIFRPG

14.28

-3.92

-3.09

EPRPRRIPP

14.50

-9.14

-8.31

Q12412

AYDPNHRPP

14.76

-6.18

-5.35

PQPPPAYDP

15.63

-7.10

-6.27

PPPAYDPNH

15.66

-6.90

-6.07

Q08412

LPTQPVRKN

13.39

-10.56

-9.73

PPQLPTRTK

13.45

-8.85

-8.02

KNSRPQQPE

13.75

-5.06

-4.23

P38216

QYSRPSNPP

14.47

-6.53

-5.70

P53933

PPPLPNRQL

12.73

-12.70

-11.87

PPPIPSTQK

13.59

-8.80

-7.97

PPLPNRQLP

13.72

-9.76

-8.93

Q12446

PPPPPHRHV

10.62

-10.39

-9.56

PPPRRGPAP

11.42

-9.06

-8.23

PPPPPRRGP

12.45

-11.25

-10.42

P38266

PPLKPGQKT

9.17

-8.05

-7.22

PPPKPFRHG

9.55

-9.76

-8.93

PPPKPFRHT

9.60

-9.84

-9.01

P40483

PASKPSVPP

13.43

-7.91

-7.08

PSVPPRNYF

14.05

-7.27

-6.44

KPSVPPRNY

14.21

-10.45

-9.62

P07244

TSEMPGMYP

12.72

-8.65

-7.82

SEMPGMYPP

15.85

-7.19

-6.36

P40563

PSERPKRRA

10.20

-5.97

-5.14

PPTPAGTPN

14.01

-7.68

-6.85

PPPVPKKPS

14.04

-8.37

-7.54

Q07533

IPPVPSRYS

11.63

-7.66

-6.83

KSPKAYPKL

11.66

-6.47

-5.64

PKSPKAYPK

12.02

-7.07

-6.24

P53901

LNSPKLPPL

12.61

-7.80

-6.97

MAMRPIPPL

13.57

-8.03

-7.20

RPIPPLPTE

13.78

-8.45

-7.62

P37254

GPGPGNPNN

15.27

-6.70

-5.87

Q12489

SYSRPSAPP

14.38

-6.49

-5.66

 


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