ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-15.PDB
Scoring matrix: PIN3_1CKB-15_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.22
Foldx random average score for Saccharomyces cerevisiae: 14.197

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2757445
Proteins after random average filtering: 6104
 Total fragments: 1273203
Proteins after disorder filtering: 3716
 Total fragments: 52775
Proteins after pattern filtering: 1692
 Total fragments: 6971
Proteins after MINT filtering: 23
 Total fragments: 200


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.22

-1.85

0.00

Best peptides

RPRFIIKMQ

0.00

-7.00

-5.15

         
Interactors      
Q06604

PLLPTRPNK

11.86

-5.08

-3.23

RVKPAPPVS

12.05

-5.58

-3.73

EKGPRMPSR

12.19

-5.37

-3.52

P24583

LPPQPRKHD

11.01

-7.19

-5.34

RANAPLPPQ

12.74

-7.12

-5.27

PPQPRKHDK

13.86

-6.45

-4.60

Q04322

QAPLDRPQL

12.06

-8.13

-6.28

TPPTLPPRR

12.09

-6.88

-5.03

PPTLPPRRI

13.56

-8.33

-6.48

P19812

SPIFRPGNI

9.90

-5.62

-3.77

RPRRIPPTD

10.75

-6.30

-4.45

PRPRRIPPT

10.97

-5.77

-3.92

P15891

PPPPPRRAT

11.02

-8.16

-6.31

PPLPSRNVA

13.35

-4.45

-2.60

QPPLPSRNV

13.45

-7.79

-5.94

Q12344

PKLPPRGKQ

10.53

-4.71

-2.86

PPLPPRQNV

11.78

-7.86

-6.01

SSPPLPPRQ

13.38

-2.79

-0.94

P39521

AQPKPKPAQ

12.46

-3.70

-1.85

VPDRPPSQL

12.97

-8.32

-6.47

HVPDRPPSQ

13.13

-3.03

-1.18

P40325

RPHQRPSTM

8.81

-9.51

-7.66

RPPRPAANL

9.51

-10.37

-8.52

RPSTMPATS

9.85

-7.03

-5.18

Q08601

RPMAPPPNQ

8.33

-7.44

-5.59

PMAPPPNQQ

12.95

-5.11

-3.26

Q12168

DPYFPQFRS

10.19

-4.72

-2.87

QHPVPKPNI

10.91

-6.74

-4.89

PPLPPRANV

11.62

-6.61

-4.76

Q12412

RPPQPPPAY

10.93

-7.07

-5.22

YDPNHRPPS

12.40

-4.04

-2.19

PPAYDPNHR

13.07

-6.45

-4.60

Q08412

LPPEPLDTT

10.67

-6.81

-4.96

VPPQLPTRT

11.52

-5.93

-4.08

PQLPTRTKS

12.24

-3.81

-1.96

P53118

NPHDLPSHL

12.58

-5.85

-4.00

P38216

RPSNPPPSS

10.90

-6.55

-4.70

P53933

PPPPPIPST

10.22

-7.10

-5.25

PPPPIPSTQ

11.69

-5.63

-3.78

APPPLPNRQ

11.82

-5.22

-3.37

Q12446

FPIPEIPST

8.59

-6.01

-4.16

RPLPQLPNR

9.49

-9.24

-7.39

PPPPPMRTT

10.05

-8.36

-6.51

P38266

QPPVPVRMQ

7.22

-9.48

-7.63

PPKPFRRSQ

10.15

-7.05

-5.20

KPPVVPKKK

10.32

-8.39

-6.54

P40483

KPSVPPRNY

9.39

-7.62

-5.77

PSVPPRNYF

12.95

-3.57

-1.72

P07244

MPGMYPPGH

14.09

-6.47

-4.62

P40563

RAPPPVPKK

12.60

-7.68

-5.83

PPPVPKKPS

12.65

-7.00

-5.15

NPGQLPPSL

12.65

-6.29

-4.44

Q07533

IPPVPSRYS

11.75

-5.53

-3.68

PPLPDLDNM

11.77

-7.93

-6.08

DPHFPYGTW

11.94

-3.45

-1.60

P53901

PPIPTRDDM

9.95

-8.07

-6.22

LPPIPTRDD

10.48

-7.30

-5.45

PPLPPIPTR

10.68

-7.12

-5.27

Q12489

RPSAPPPGY

11.89

-7.07

-5.22

 


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