ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKB-12.PDB
Scoring matrix: PIN3_1CKB-12_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.1
Foldx random average score for Saccharomyces cerevisiae: 10.981

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2763549
Proteins after random average filtering: 6104
 Total fragments: 1002501
Proteins after disorder filtering: 3837
 Total fragments: 63613
Proteins after pattern filtering: 1896
 Total fragments: 10456
Proteins after MINT filtering: 25
 Total fragments: 358


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.10

-1.27

0.00

Best peptides

WRWMPFWR

0.00

-5.39

-4.12

         
Interactors      
Q06604

PRMPSRGR

5.63

-5.47

-4.20

NIPSSKPA

5.73

-4.03

-2.76

FEKGPRMP

5.98

-3.48

-2.21

P24583

LPPQPRKH

8.60

-3.84

-2.57

PLPPQPRK

9.22

-3.38

-2.11

PPQPRKHD

9.31

-3.90

-2.63

Q04322

STPPTLPP

7.99

-4.93

-3.66

QAPLDRPQ

8.19

-3.52

-2.25

TSPPLPPR

8.88

-3.94

-2.67

Q12168

PYFPQFRS

4.72

-6.71

-5.44

RGPPPLPP

7.38

-5.06

-3.79

QHPVPKPN

7.80

-4.79

-3.52

P15891

PEKKPKEN

5.73

-3.89

-2.62

ATPEKKPK

7.00

-3.60

-2.33

PPPPPRRA

7.73

-4.49

-3.22

Q12344

PLPPRQNV

8.10

-4.73

-3.46

TSPKLPPR

8.31

-3.07

-1.80

SSPPLPPR

8.89

-3.41

-2.14

P39521

AQPKPKPA

5.61

-5.92

-4.65

PKPKPAQD

9.50

-2.69

-1.42

QTPHVPDR

10.13

-2.15

-0.88

P40325

PRPPPRPQ

5.99

-4.53

-3.26

SRPHQRPS

6.37

-4.72

-3.45

QRPSTMPA

6.49

-4.76

-3.49

Q08601

QRPMAPPP

7.72

-4.32

-3.05

PGPPPMAY

8.01

-5.67

-4.40

GYQRPMAP

8.16

-6.56

-5.29

Q12532

PFKPYING

9.74

-2.61

-1.34

P19812

PRPRRIPP

6.92

-5.61

-4.34

DHSPIFRP

8.19

-5.49

-4.22

HSPIFRPG

8.22

-5.82

-4.55

Q12412

YDPNHRPP

7.37

-3.58

-2.31

AYDPNHRP

9.33

-3.44

-2.17

PNHRPPSS

9.77

-1.92

-0.65

Q08412

KKWQPLPP

4.57

-5.18

-3.91

DVPPQLPT

7.89

-4.85

-3.58

NSRPQQPE

8.48

-4.10

-2.83

P53118

ENPHDLPS

7.89

-3.43

-2.16

P38216

SRPSNPPP

8.23

-3.43

-2.16

YSRPSNPP

10.34

-3.11

-1.84

P53933

DLPMELPH

7.33

-5.37

-4.10

VAPPPLPN

7.49

-5.48

-4.21

TRRRPPPP

7.67

-4.83

-3.56

Q12446

TNPFPFPV

6.13

-6.30

-5.03

SNPFPFPI

6.15

-6.45

-5.18

PPPPPHRH

7.44

-5.76

-4.49

P38266

IMPPPKPF

5.22

-4.89

-3.62

KDPKSFPP

5.34

-5.81

-4.54

PPPKPFRR

5.34

-7.20

-5.93

P40483

DAPASKPS

7.77

-3.57

-2.30

SKPSVPPR

8.04

-2.90

-1.63

ASKPSVPP

10.18

-2.81

-1.54

P07244

SEMPGMYP

5.54

-7.15

-5.88

EMPGMYPP

8.76

-3.04

-1.77

PGMYPPGH

9.74

-3.32

-2.05

P40563

PSERPKRR

7.28

-5.55

-4.28

VNPGQLPP

8.42

-4.42

-3.15

PPPVPKKP

9.26

-4.90

-3.63

Q07533

SPKSPKAY

7.75

-2.67

-1.40

KSPKAYPK

7.82

-4.50

-3.23

KSDPHFPY

8.15

-4.03

-2.76

P53901

MAMRPIPP

6.92

-7.80

-6.53

SSPNSHPH

7.22

-5.39

-4.12

GLNSPKLP

8.02

-1.86

-0.59

P37254

PGPGNPNN

10.79

-2.42

-1.15

Q12489

SRPSAPPP

8.06

-2.86

-1.59

YSRPSAPP

10.28

-2.68

-1.41

 


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