ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-21.PDB
Scoring matrix: PIN3_1CKA-21_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 13.53
Foldx random average score for Saccharomyces cerevisiae: 14.662

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2751341
Proteins after random average filtering: 6104
 Total fragments: 1542495
Proteins after disorder filtering: 3876
 Total fragments: 71982
Proteins after pattern filtering: 1543
 Total fragments: 4278
Proteins after MINT filtering: 22
 Total fragments: 98


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

13.53

-1.16

0.00

Best peptides

RWKIGIPHRR

0.00

6.21

7.37

         
Interactors      
Q06604

EKGPRMPSRG

8.56

-4.51

-3.35

PTPPSPPAKR

9.00

-3.10

-1.94

PLLPTRPNKA

12.35

-3.11

-1.95

P40325

SRPHQRPSTM

10.18

-2.52

-1.36

YVQPGDPRLG

10.53

-3.83

-2.67

PGDPRLGGVL

10.83

-1.81

-0.65

P38260

GGGPDDPTLM

10.91

-3.61

-2.45

Q04322

TPPTLPPRRI

12.46

-4.27

-3.11

TPSKSPTSAV

13.65

-2.10

-0.94

Q12168

DDPYFPQFRS

10.32

-4.26

-3.10

PNRPGGTTNR

10.77

-3.56

-2.40

NDDPYFPQFR

11.44

-2.70

-1.54

P15891

TPSPAPAAKI

9.72

-3.35

-2.19

DEPEGEPDVK

11.47

-0.77

0.39

AAQPPLPSRN

13.43

-3.41

-2.25

Q12344

SSPPLPPRQN

14.03

-1.11

0.05

P39521

HVPDRPPSQL

10.28

-0.94

0.22

P24583

PPQPRKHDKT

8.68

-2.19

-1.03

Q12532

PFKPYINGGD

13.45

-3.32

-2.16

P19812

HSPIFRPGNI

10.56

-3.11

-1.95

NSPEASPSLA

11.04

-3.05

-1.89

SPIFRPGNIF

13.09

-2.24

-1.08

Q12412

DPNHRPPSSS

14.11

0.04

1.20

Q08412

DVPPQLPTRT

8.60

-4.87

-3.71

IELPTQPVRK

11.28

-4.70

-3.54

PLPPEPLDTT

13.09

-0.89

0.27

P53118

NPHDLPSHLG

12.05

-3.81

-2.65

ENPHDLPSHL

13.20

-1.49

-0.33

P53933

VSYPGNPTSR

10.07

-1.45

-0.29

PPPPIPSTQK

13.45

-2.21

-1.05

APPPLPNRQL

13.99

-3.43

-2.27

Q12446

RPLPQLPNRN

9.63

-4.45

-3.29

FPIPEIPSTQ

10.50

-0.49

0.67

PIPPTLPSTT

11.55

-0.87

0.29

P38266

PGHPSEEDRN

10.37

-2.36

-1.20

EVLPGHPSEE

10.62

-1.80

-0.64

NIYPIEPSLD

10.93

-2.82

-1.66

P07244

MPGMYPPGHY

12.04

-3.91

-2.75

P40563

NPGQLPPSLE

11.03

-3.22

-2.06

NSQPQGPSDT

11.59

-1.46

-0.30

Q07533

KSDPHFPYGT

11.67

-1.27

-0.11

PHFPYGTWKG

11.86

-2.63

-1.47

PPLPDLDNMR

11.92

-4.40

-3.24

P53901

PPIPTRDDMS

11.89

-1.71

-0.55

DPIILPPTFS

12.00

-4.27

-3.11

KLPPLPTTSN

14.54

-2.26

-1.10

P37254

PGNPNNGAQD

12.93

-1.38

-0.22

GPGPGNPNNG

14.52

-1.53

-0.37

 


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