ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-20.PDB
Scoring matrix: PIN3_1CKA-20_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.61
Foldx random average score for Saccharomyces cerevisiae: 18.437

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2757445
Proteins after random average filtering: 6104
 Total fragments: 1296266
Proteins after disorder filtering: 3974
 Total fragments: 87394
Proteins after pattern filtering: 1904
 Total fragments: 9511
Proteins after MINT filtering: 23
 Total fragments: 238


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.61

-3.14

0.00

Best peptides

FRFRSGRWM

0.00

-1.04

2.10

         
Interactors      
Q06604

MKNKPKPTP

13.01

-9.88

-6.74

PPSPPAKRI

13.20

-8.54

-5.40

LPTRPNKAE

13.65

-8.91

-5.77

P24583

LPPQPRKHD

13.16

-9.67

-6.53

APLPPQPRK

14.90

-8.84

-5.70

PPQPRKHDK

16.70

-7.21

-4.07

P38260

GGGPDDPTL

16.17

-5.17

-2.03

Q04322

GNATPSKSP

16.76

-5.29

-2.15

NATPSKSPT

17.24

-4.22

-1.08

DQAPLDRPQ

17.64

-5.36

-2.22

P19812

NSPEASPSL

14.76

-4.02

-0.88

PRPRRIPPT

16.34

-5.51

-2.37

DHSPIFRPG

17.22

-4.50

-1.36

P15891

RRATPEKKP

10.36

-7.85

-4.71

KSFTPSKSP

14.05

-4.91

-1.77

PPPPPRRAT

14.84

-8.52

-5.38

Q12344

PKLPPRGKQ

15.42

-8.98

-5.84

PPLPPRQNV

16.21

-8.16

-5.02

TSSPPLPPR

17.44

-6.44

-3.30

P39521

TPHVPDRPP

14.99

-9.54

-6.40

AQPKPKPAQ

15.77

-7.53

-4.39

PKPKPAQDN

17.02

-5.57

-2.43

P40325

RPPRPAANL

11.85

-9.45

-6.31

PRPPPRPQQ

12.91

-7.76

-4.62

PRPQQNPSL

13.01

-6.21

-3.07

Q08601

YAPPPGPPP

15.74

-7.89

-4.75

PGPPPMAYN

17.69

-6.44

-3.30

Q12168

VPNRPGGTT

12.25

-6.98

-3.84

QHPVPKPNI

13.00

-7.15

-4.01

NDDPYFPQF

15.61

-6.28

-3.14

Q12412

PPPAYDPNH

17.23

-5.68

-2.54

AYDPNHRPP

17.30

-6.71

-3.57

Q08412

LPTQPVRKN

14.62

-9.13

-5.99

LPPEPLDTT

14.87

-6.77

-3.63

DVPPQLPTR

16.58

-7.05

-3.91

P38216

YSRPSNPPP

17.31

-5.69

-2.55

QYSRPSNPP

18.18

-7.63

-4.49

P53933

PPIPSTQKP

16.09

-9.45

-6.31

VAPPPLPNR

16.50

-7.31

-4.17

PPPPPIPST

17.15

-6.69

-3.55

Q12446

PPPPPHRHV

11.49

-8.87

-5.73

PPPPPMRTT

13.34

-9.24

-6.10

APTTPAPAL

13.40

-6.49

-3.35

P38266

PRPPPSRSS

11.71

-7.14

-4.00

FLPPPKPFR

11.78

-9.41

-6.27

FQPPPKPFR

12.36

-9.44

-6.30

P40483

PSVPPRNYF

15.32

-8.16

-5.02

DAPASKPSV

16.74

-3.06

0.08

TKDAPASKP

16.86

-8.33

-5.19

P07244

TSEMPGMYP

13.65

-6.95

-3.81

P40563

PSERPKRRA

13.51

-8.08

-4.94

EPPTPAGTP

14.73

-6.41

-3.27

NSQPQGPSD

15.02

-2.73

0.41

Q07533

IPPVPSRYS

12.19

-7.72

-4.58

PHFPYGTWK

12.85

-5.35

-2.21

KSPKAYPKL

13.63

-6.53

-3.39

P53901

RPIPPLPTE

13.96

-8.54

-5.40

PKLPPLPTT

15.16

-7.41

-4.27

SSPNSHPHP

15.42

-6.37

-3.23

Q12489

YSRPSAPPP

16.74

-5.95

-2.81

SYSRPSAPP

18.18

-6.10

-2.96

 


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