ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-13.PDB
Scoring matrix: PIN3_1CKA-13_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.87
Foldx random average score for Saccharomyces cerevisiae: 9.480

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2763549
Proteins after random average filtering: 6104
 Total fragments: 1213699
Proteins after disorder filtering: 3950
 Total fragments: 69534
Proteins after pattern filtering: 1967
 Total fragments: 12699
Proteins after MINT filtering: 24
 Total fragments: 414


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.87

-2.30

0.00

Best peptides

MHRKHPWH

0.00

2.04

4.34

         
Interactors      
Q06604

LPTRPNKA

3.88

-7.83

-5.53

KPLLPTRP

4.88

-8.80

-6.50

NKPKPTPP

5.67

-5.54

-3.24

P24583

LPPQPRKH

3.46

-8.71

-6.41

NAPLPPQP

8.03

-6.98

-4.68

APLPPQPR

8.30

-5.04

-2.74

P38260

GPDDPTLM

7.34

-6.43

-4.13

Q04322

PPTLPPRR

6.04

-9.06

-6.76

SPPLPPRA

6.07

-8.85

-6.55

APLDRPQL

7.64

-4.43

-2.13

P19812

RPRRIPPT

5.92

-7.27

-4.97

EPRPRRIP

6.39

-6.81

-4.51

DHSPIFRP

7.28

-4.54

-2.24

P15891

TPEKKPKE

5.04

-5.36

-3.06

APPPPPRR

5.31

-7.65

-5.35

QPPLPSRN

5.79

-9.37

-7.07

Q12344

SPKLPPRG

6.11

-8.78

-6.48

SPPLPPRQ

6.27

-8.84

-6.54

PPLPPRQN

7.66

-6.42

-4.12

P39521

VPDRPPSQ

6.48

-6.00

-3.70

PKPKPAQD

6.49

-5.79

-3.49

TPHVPDRP

6.54

-7.84

-5.54

P40325

QPPRPPRP

4.21

-8.61

-6.31

RPPRPAAN

4.96

-6.04

-3.74

QPRPPPRP

5.02

-7.39

-5.09

Q08601

RPMAPPPN

5.86

-6.71

-4.41

PPGPPPMA

6.50

-7.12

-4.82

AYNRPVYP

6.68

-6.54

-4.24

Q12168

PPPLPPRA

5.73

-9.24

-6.94

PPPVPNRP

5.95

-7.49

-5.19

DPYFPQFR

6.09

-7.20

-4.90

Q12412

RPPQPPPA

4.94

-7.66

-5.36

YDPNHRPP

5.94

-3.27

-0.97

DPNHRPPS

7.23

-4.29

-1.99

Q08412

LPTQPVRK

5.03

-8.26

-5.96

KKWQPLPP

6.13

-4.59

-2.29

PPQLPTRT

6.79

-9.13

-6.83

P53118

VENPHDLP

7.63

-4.09

-1.79

PHDLPSHL

8.03

-6.43

-4.13

NPHDLPSH

9.33

-3.94

-1.64

P38216

RPSNPPPS

5.63

-7.41

-5.11

QYSRPSNP

8.80

-5.31

-3.01

YSRPSNPP

9.08

-2.24

0.06

P53933

RPPPPPIP

4.43

-8.53

-6.23

RVAPPPLP

5.46

-7.22

-4.92

RRPPPPPI

5.66

-6.58

-4.28

Q12446

KHSLPPLP

4.58

-7.89

-5.59

LPQLPNRN

5.17

-9.69

-7.39

APPPPPRR

5.31

-7.65

-5.35

P38266

MPPPKPFR

3.22

-9.26

-6.96

LPPPKPFR

3.55

-7.76

-5.46

FPPPPLKP

4.14

-8.35

-6.05

P40483

KPSVPPRN

3.96

-8.07

-5.77

KDAPASKP

6.93

-4.94

-2.64

APASKPSV

7.92

-3.06

-0.76

P07244

EMPGMYPP

9.09

-2.49

-0.19

P40563

PPPVPKKP

5.66

-6.43

-4.13

TPKVPERP

6.35

-7.47

-5.17

RRAPPPVP

6.69

-6.69

-4.39

Q07533

LPPLPPLP

4.51

-9.74

-7.44

MPNSPKKP

4.85

-7.18

-4.88

IPPVPSRY

5.02

-7.80

-5.50

P53901

LPPIPTRD

3.81

-8.54

-6.24

MRPIPPLP

3.87

-7.64

-5.34

NYNQPPLP

5.82

-6.47

-4.17

Q12489

RPSAPPPG

6.04

-6.71

-4.41

SYSRPSAP

8.07

-5.09

-2.79

YSRPSAPP

8.99

-2.53

-0.23

 


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