ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1CKA-12.PDB
Scoring matrix: PIN3_1CKA-12_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 8.65
Foldx random average score for Saccharomyces cerevisiae: 9.404

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1075
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 6104
 Total fragments: 2763549
Proteins after random average filtering: 6104
 Total fragments: 1348247
Proteins after disorder filtering: 4078
 Total fragments: 129321
Proteins after pattern filtering: 2028
 Total fragments: 16210
Proteins after MINT filtering: 26
 Total fragments: 484


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

8.65

-1.17

0.00

Best peptides

YEFPRRWR

0.00

-0.64

0.53

         
Interactors      
Q06604

SSPPPLPT

3.84

-5.47

-4.30

PRMPSRGR

4.69

-6.04

-4.88

EEKPLLPT

5.04

-4.45

-3.29

P24583

PLPPQPRK

5.05

-4.55

-3.38

LPPQPRKH

6.01

-4.27

-3.10

RANAPLPP

6.92

-2.70

-1.54

P38260

GGPDDPTL

7.92

-1.78

-0.61

GGGPDDPT

8.34

-0.14

1.02

Q04322

STPPTLPP

4.54

-5.21

-4.04

TSPPLPPR

5.20

-3.85

-2.69

ATPSKSPT

5.23

-2.27

-1.11

Q12168

RGPPPLPP

4.05

-5.28

-4.12

PLPPRANV

5.65

-3.53

-2.36

PYFPQFRS

6.03

-5.54

-4.38

P15891

PPPPPRRA

4.32

-5.82

-4.66

AAPPPPPR

5.08

-4.44

-3.28

KTPSPAPA

5.08

-2.12

-0.96

Q12344

SSPPLPPR

5.20

-4.06

-2.89

TSSPPLPP

5.95

-3.76

-2.59

TSPKLPPR

6.08

-4.17

-3.00

P39521

PKPKPAQD

5.59

-3.36

-2.19

HVPDRPPS

6.82

-2.77

-1.61

AQPKPKPA

6.90

-6.52

-5.35

P40325

PRPPPRPQ

3.16

-5.37

-4.21

QRPSTMPA

4.30

-4.55

-3.38

QNPSLPWT

4.71

-3.01

-1.84

Q08601

PGPPPMAY

4.49

-5.24

-4.08

YAPPPGPP

5.10

-3.36

-2.19

QRPMAPPP

5.97

-3.63

-2.46

Q12532

PFKPYING

7.84

-3.59

-2.42

P19812

PRPRRIPP

4.73

-4.19

-3.03

TSPSNSPE

5.68

-2.76

-1.59

PIFRPGNI

6.12

-2.23

-1.06

Q12412

YDPNHRPP

4.68

-4.20

-3.04

PQPPPAYD

5.28

-3.64

-2.48

PAYDPNHR

6.74

-1.87

-0.71

Q08412

DVPPQLPT

4.41

-5.09

-3.92

PLPPEPLD

6.90

-3.95

-2.79

ELPTQPVR

7.13

-2.73

-1.56

P53118

ENPHDLPS

5.80

-4.00

-2.84

VENPHDLP

6.57

-2.15

-0.98

PHDLPSHL

9.00

-1.05

0.11

P38216

SRPSNPPP

5.54

-3.31

-2.15

PSNPPPSS

7.38

-2.49

-1.33

YSRPSNPP

7.76

-3.31

-2.15

P53933

VAPPPLPN

4.12

-5.35

-4.18

RRPPPPPI

4.58

-4.55

-3.38

VSYPGNPT

5.21

-3.34

-2.17

Q12446

PPPPPMRT

4.29

-5.97

-4.80

PPPPPRRG

4.37

-6.05

-4.88

PIPPTLPS

4.67

-5.12

-3.96

P38266

PRPPPSRS

3.44

-4.06

-2.89

VEPPPPPS

4.43

-4.74

-3.58

PLPPPRGQ

4.43

-5.71

-4.54

P40483

SKPSVPPR

5.17

-3.31

-2.15

KDAPASKP

6.57

-2.03

-0.86

ASKPSVPP

7.52

-3.04

-1.88

P07244

SEMPGMYP

4.68

-6.63

-5.46

EMPGMYPP

6.69

-5.32

-4.16

PGMYPPGH

8.39

-3.20

-2.04

P40563

SEPPTPAG

5.64

-4.52

-3.35

VNPGQLPP

5.72

-3.96

-2.79

RAPPPVPK

5.72

-3.67

-2.50

Q07533

SMPNSPKK

5.61

-2.99

-1.83

PHFPYGTW

5.75

-2.88

-1.71

PLPPLPPL

5.83

-4.10

-2.93

P53901

PLPPIPTR

5.94

-3.76

-2.59

NQPPLPPI

5.99

-3.94

-2.77

PIPPLPTE

6.18

-3.48

-2.31

P37254

VGPGPGNP

7.26

-2.00

-0.83

PGNPNNGA

7.92

-2.06

-0.90

PGPGNPNN

8.30

-2.39

-1.23

Q12489

SRPSAPPP

5.37

-3.00

-1.84

PSAPPPGY

7.41

-3.09

-1.92

YSRPSAPP

7.71

-3.03

-1.86

 


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