ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-28.PDB
Scoring matrix: PEX13_1N5Z-28_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.27
Foldx random average score for Saccharomyces cerevisiae: 16.806

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1058057
Proteins after random average filtering: 2766
 Total fragments: 476799
Proteins after disorder filtering: 1568
 Total fragments: 20219
Proteins after pattern filtering: 731
 Total fragments: 3960
Proteins after MINT filtering: 7
 Total fragments: 53


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.27

5.29

0.00

Best peptides

MPPMRPHPRK

0.00

-7.27

-12.56

         
Interactors      
Q04370

DIPRPPFSSH

11.49

-9.46

-14.75

EDIPRPPFSS

14.09

-3.82

-9.11

IPRPPFSSHS

15.30

-6.55

-11.84

P40450

PPLPDLFKTK

10.66

-5.89

-11.18

APPPLPDLFK

11.37

-6.00

-11.29

PPPPPPLPQS

12.29

-9.95

-15.24

P47135

SKTPRASPSR

12.72

-5.46

-10.75

GPLPEPLSGR

12.72

-5.02

-10.31

CPFPLPPPNV

12.75

-9.67

-14.96

P15274

QNPKNKPGWV

11.40

-6.76

-12.05

YPPPPKPSYN

12.44

-8.45

-13.74

PPPKPSYNSD

13.22

-6.89

-12.18

P53112

SISPNGIPGI

14.17

-6.01

-11.30

Q08446

SSHSPISPLK

14.90

-5.77

-11.06

Q12110

SPVAPSPNHR

12.71

-8.17

-13.46

 


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