ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-25.PDB
Scoring matrix: PEX13_1N5Z-25_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.72
Foldx random average score for Saccharomyces cerevisiae: 25.338

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1060823
Proteins after random average filtering: 2766
 Total fragments: 667916
Proteins after disorder filtering: 1743
 Total fragments: 57832
Proteins after pattern filtering: 814
 Total fragments: 7840
Proteins after MINT filtering: 7
 Total fragments: 88


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.72

5.28

0.00

Best peptides

RRPPRPRRP

0.00

-6.95

-12.23

         
Interactors      
Q04370

EDIPRPPFS

11.36

-4.76

-10.04

PRPPFSSHS

12.61

-3.77

-9.05

DIPRPPFSS

15.46

-3.85

-9.13

P40450

KLPQLPPPP

7.26

-6.33

-11.61

QLPPPPPPP

7.98

-6.27

-11.55

PPPPPPPLP

8.79

-6.69

-11.97

P47135

EQCPFPLPP

10.57

-3.95

-9.23

YFSYPGVFP

12.18

-1.96

-7.24

CPFPLPPPN

13.23

-2.63

-7.91

P15274

VVYPPPPKP

7.96

-5.75

-11.03

PPPPKPSYN

9.81

-4.72

-10.00

GWVVYPPPP

11.32

-3.14

-8.42

P53112

SISPNGIPG

17.61

-2.72

-8.00

SPNGIPGID

18.37

0.37

-4.91

FSISPNGIP

18.48

-0.78

-6.06

Q08446

NSSHSPISP

15.22

0.18

-5.10

SHSPISPLK

19.45

-0.28

-5.56

Q12110

GSPVAPSPN

14.67

-2.09

-7.37

QGSPVAPSP

15.24

-1.63

-6.91

NSQGSPVAP

15.73

-0.80

-6.08

 


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