ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-19.PDB
Scoring matrix: PEX13_1N5Z-19_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.83
Foldx random average score for Saccharomyces cerevisiae: 14.867

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1060823
Proteins after random average filtering: 2766
 Total fragments: 457834
Proteins after disorder filtering: 1653
 Total fragments: 23358
Proteins after pattern filtering: 713
 Total fragments: 2796
Proteins after MINT filtering: 7
 Total fragments: 31


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.83

-3.39

0.00

Best peptides

RPSMRGRRI

0.00

-6.95

-3.56

         
Interactors      
Q04370

IPRPPFSSH

10.09

-7.57

-4.18

DEDIPRPPF

12.11

-5.71

-2.32

PRPPFSSHS

14.54

-5.29

-1.90

P40450

PPLPNGLLS

10.18

-6.85

-3.46

PPLPDLFKT

12.39

-7.46

-4.07

PPAPPLPNG

12.62

-8.21

-4.82

P47135

PRASPSRSK

11.96

-5.57

-2.18

YFSYPGVFP

12.04

-7.02

-3.63

KTPRASPSR

13.85

-4.85

-1.46

P15274

PKNKPGWVV

7.18

-8.48

-5.09

YPPPPKPSY

10.28

-7.54

-4.15

QNPKNKPGW

10.90

-3.01

0.38

P53112

SISPNGIPG

13.79

-3.67

-0.28

Q08446

SHSPISPLK

13.59

-5.40

-2.01

Q12110

SPVAPSPNH

11.03

-5.16

-1.77

QGSPVAPSP

14.13

-6.52

-3.13

 


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