ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-14.PDB
Scoring matrix: PEX13_1N5Z-14_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.49
Foldx random average score for Saccharomyces cerevisiae: 14.993

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1060823
Proteins after random average filtering: 2766
 Total fragments: 499599
Proteins after disorder filtering: 1585
 Total fragments: 19089
Proteins after pattern filtering: 660
 Total fragments: 2514
Proteins after MINT filtering: 7
 Total fragments: 35


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.49

-1.18

0.00

Best peptides

WWFIIHKKR

0.00

-6.91

-5.73

         
Interactors      
Q04370

IPRPPFSSH

13.31

-7.60

-6.42

DEDIPRPPF

13.52

-7.64

-6.46

P40450

SSPKLFPRL

10.44

-10.58

-9.40

APPLPNGLL

11.07

-10.56

-9.38

PPPLPQSLL

11.99

-10.18

-9.00

P47135

KTPRASPSR

9.37

-10.14

-8.96

PLPEPLSGR

11.77

-5.20

-4.02

PFPLPPPNV

13.21

-7.69

-6.51

P15274

NPKNKPGWV

13.05

-5.96

-4.78

PPPKPSYNS

13.14

-6.37

-5.19

WVVYPPPPK

13.91

-5.99

-4.81

P53112

ISPNGIPGI

13.49

-4.41

-3.23

Q08446

SHSPISPLK

13.16

-3.27

-2.09

SSHSPISPL

14.61

-5.60

-4.42

Q12110

PVAPSPNHR

12.72

-8.35

-7.17

SPVAPSPNH

14.56

-4.85

-3.67

GSPVAPSPN

14.90

-4.66

-3.48

 


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