ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-13.PDB
Scoring matrix: PEX13_1N5Z-13_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 20.71
Foldx random average score for Saccharomyces cerevisiae: 18.700

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1063589
Proteins after random average filtering: 2766
 Total fragments: 635301
Proteins after disorder filtering: 1737
 Total fragments: 36621
Proteins after pattern filtering: 808
 Total fragments: 5876
Proteins after MINT filtering: 7
 Total fragments: 77


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

20.71

-2.45

0.00

Best peptides

RPRRQPRR

0.00

-10.51

-8.06

         
Interactors      
Q04370

DIPRPPFS

9.85

-9.70

-7.25

IPRPPFSS

15.96

-7.64

-5.19

DEDIPRPP

16.14

-6.22

-3.77

P40450

PPPLPDLF

10.91

-10.61

-8.16

LPQLPPPP

11.46

-10.35

-7.90

PPPPPPLP

13.06

-9.92

-7.47

P47135

FPLPPPNV

12.96

-9.49

-7.04

TPRASPSR

13.58

-5.74

-3.29

QCPFPLPP

14.51

-6.58

-4.13

P15274

PPPKPSYN

11.18

-9.34

-6.89

WVVYPPPP

13.75

-7.14

-4.69

PKNKPGWV

14.29

-6.88

-4.43

P53112

PNGIPGID

15.91

-5.96

-3.51

SISPNGIP

17.31

-5.57

-3.12

Q08446

HSPISPLK

15.40

-4.61

-2.16

Q12110

SPVAPSPN

16.73

-5.69

-3.24

PVAPSPNH

17.19

-3.47

-1.02

SQGSPVAP

18.23

-5.32

-2.87

 


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