ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1N5Z-12.PDB
Scoring matrix: PEX13_1N5Z-12_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.68
Foldx random average score for Saccharomyces cerevisiae: 11.651

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1063589
Proteins after random average filtering: 2766
 Total fragments: 430776
Proteins after disorder filtering: 1666
 Total fragments: 25672
Proteins after pattern filtering: 770
 Total fragments: 4409
Proteins after MINT filtering: 7
 Total fragments: 62


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.68

-1.61

0.00

Best peptides

YKMRRRRK

0.00

-8.51

-6.90

         
Interactors      
Q04370

EDIPRPPF

7.03

-6.53

-4.92

DIPRPPFS

7.21

-6.88

-5.27

DEDIPRPP

10.27

-5.68

-4.07

P40450

SPKLFPRL

7.21

-6.64

-5.03

GAVPPPPP

8.88

-5.14

-3.53

AVPPPPPP

9.00

-4.87

-3.26

P47135

FSYPGVFP

7.43

-6.36

-4.75

PRASPSRS

9.40

-4.09

-2.48

CPFPLPPP

9.51

-5.08

-3.47

P15274

VYPPPPKP

7.31

-5.81

-4.20

VVYPPPPK

7.90

-5.42

-3.81

DQNPKNKP

8.70

-4.81

-3.20

P53112

ISPNGIPG

10.10

-3.57

-1.96

Q08446

HSPISPLK

9.64

-3.73

-2.12

SSHSPISP

10.61

-2.20

-0.59

Q12110

PVAPSPNH

10.47

-4.12

-2.51

GSPVAPSP

11.28

-2.73

-1.12

 


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