ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-7.PDB
Scoring matrix: PEX13_1JQQ-7_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 15.8
Foldx random average score for Saccharomyces cerevisiae: 11.978

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1063589
Proteins after random average filtering: 2766
 Total fragments: 443808
Proteins after disorder filtering: 1610
 Total fragments: 19109
Proteins after pattern filtering: 674
 Total fragments: 3048
Proteins after MINT filtering: 6
 Total fragments: 45


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

15.80

-2.47

0.00

Best peptides

MKRIFPFS

0.00

-7.79

-5.32

         
Interactors      
Q04370

DIPRPPFS

6.55

-9.78

-7.31

IPRPPFSS

8.77

-4.28

-1.81

EDIPRPPF

9.95

-5.82

-3.35

P40450

PKLFPRLS

6.08

-7.66

-5.19

PPPPLPQS

7.32

-6.42

-3.95

PPPLPDLF

7.40

-6.80

-4.33

P47135

YPGVFPVS

7.46

-7.19

-4.72

KTPRASPS

8.31

-4.77

-2.30

GPLPEPLS

9.27

-4.30

-1.83

P15274

PKNKPGWV

8.92

-6.59

-4.12

YPPPPKPS

9.10

-5.08

-2.61

PPPKPSYN

9.40

-8.52

-6.05

P53112

PNGIPGID

9.54

-7.09

-4.62

Q08446

HSPISPLK

9.28

-5.96

-3.49

 


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