ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-29.PDB
Scoring matrix: PEX13_1JQQ-29_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.21
Foldx random average score for Saccharomyces cerevisiae: 14.761

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1058057
Proteins after random average filtering: 2766
 Total fragments: 457723
Proteins after disorder filtering: 1518
 Total fragments: 20070
Proteins after pattern filtering: 729
 Total fragments: 4513
Proteins after MINT filtering: 7
 Total fragments: 67


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.21

-4.02

0.00

Best peptides

HYPPIRRHLR

0.00

-13.44

-9.42

         
Interactors      
Q04370

PRPPFSSHSD

8.89

-8.31

-4.29

DIPRPPFSSH

12.12

-8.51

-4.49

EDIPRPPFSS

13.68

-7.99

-3.97

P40450

APPLPNGLLS

9.60

-10.05

-6.03

PPPPPPPLPQ

10.48

-11.03

-7.01

SPKLFPRLSS

10.77

-8.59

-4.57

P47135

SYPGVFPVSG

10.39

-12.43

-8.41

ASKTPRASPS

12.41

-7.05

-3.03

EKEQCPFPLP

12.50

-10.85

-6.83

P15274

GWVVYPPPPK

10.70

-9.82

-5.80

VYPPPPKPSY

10.81

-11.18

-7.16

VVYPPPPKPS

12.39

-10.80

-6.78

P53112

SPNGIPGIDT

12.06

-8.90

-4.88

FSISPNGIPG

13.63

-8.85

-4.83

Q08446

SSHSPISPLK

12.89

-8.23

-4.21

Q12110

PVAPSPNHRS

12.54

-7.38

-3.36

GSPVAPSPNH

13.96

-9.50

-5.48

QGSPVAPSPN

14.58

-7.85

-3.83

 


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