ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-21.PDB
Scoring matrix: PEX13_1JQQ-21_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 21.11
Foldx random average score for Saccharomyces cerevisiae: 19.703

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1058057
Proteins after random average filtering: 2766
 Total fragments: 589324
Proteins after disorder filtering: 1608
 Total fragments: 24838
Proteins after pattern filtering: 593
 Total fragments: 1410
Proteins after MINT filtering: 5
 Total fragments: 11


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

21.11

-1.33

0.00

Best peptides

YWRRGRPNWR

0.00

-3.28

-1.95

         
Interactors      
P40450

PPLPDLFKTK

14.78

-5.82

-4.49

SSPKLFPRLS

15.45

-6.51

-5.18

PPLPESLSMN

16.94

-6.66

-5.33

P47135

KTPRASPSRS

15.62

-6.67

-5.34

TPRASPSRSK

17.25

-7.06

-5.73

GPLPEPLSGR

18.73

-5.30

-3.97

Q12110

PVAPSPNHRS

19.48

-5.03

-3.70

P53112

ISPNGIPGID

19.58

-2.90

-1.57

P15274

QNPKNKPGWV

14.87

-6.92

-5.59

 


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