ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PEX13_1JQQ-20.PDB
Scoring matrix: PEX13_1JQQ-20_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.76
Foldx random average score for Saccharomyces cerevisiae: 18.330

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1060823
Proteins after random average filtering: 2766
 Total fragments: 524077
Proteins after disorder filtering: 1711
 Total fragments: 39019
Proteins after pattern filtering: 764
 Total fragments: 3825
Proteins after MINT filtering: 7
 Total fragments: 33


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.76

-3.06

0.00

Best peptides

YRPKRGRSV

0.00

-8.56

-5.51

         
Interactors      
Q04370

IPRPPFSSH

11.37

-7.53

-4.47

PRPPFSSHS

13.27

-6.05

-2.99

P40450

PPLPNGLLS

12.25

-6.56

-3.50

PPLPESLSM

14.46

-6.28

-3.23

PPLPDLFKT

14.83

-4.37

-1.31

P47135

PRASPSRSK

9.72

-5.38

-2.32

KTPRASPSR

13.12

-7.76

-4.71

YFSYPGVFP

14.88

-9.43

-6.38

P15274

PKNKPGWVV

12.23

-8.32

-5.27

QNPKNKPGW

12.64

-6.75

-3.69

PPPKPSYNS

14.16

-6.80

-3.74

P53112

SISPNGIPG

14.49

-5.37

-2.31

PNGIPGIDT

16.26

-2.80

0.26

Q08446

SHSPISPLK

15.62

-3.58

-0.52

Q12110

SPVAPSPNH

14.69

-3.47

-0.42

QGSPVAPSP

15.85

-6.34

-3.28

 


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