ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-8.PDB
Scoring matrix: NBP2_1YN8-8_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.96
Foldx random average score for Saccharomyces cerevisiae: 12.016

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2181610
Proteins after random average filtering: 5077
 Total fragments: 928330
Proteins after disorder filtering: 3061
 Total fragments: 54385
Proteins after pattern filtering: 1560
 Total fragments: 10570
Proteins after MINT filtering: 7
 Total fragments: 124


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.96

-1.31

0.00

Best peptides

HWRPRWPR

0.00

-1.57

-0.26

         
Interactors      
Q01389

STPSRPVP

7.47

-4.63

-3.32

SPPPIPKT

8.79

-5.97

-4.66

SKPLPPQL

9.08

-3.34

-2.03

P53933

APPPLPNR

6.69

-6.99

-5.68

RRRPPPPP

6.98

-5.12

-3.81

TRRRPPPP

7.41

-4.52

-3.21

P48562

LNPYRPHH

5.48

-4.56

-3.25

QAPKRPDA

6.54

-5.22

-3.91

GPAPRPPS

7.51

-5.88

-4.57

Q03497

FIPSRPAP

5.31

-3.67

-2.36

KPKVKPSK

7.85

-5.66

-4.35

SFPSKNPL

8.46

-4.03

-2.72

Q12469

KPFPRPSD

7.22

-5.03

-3.72

ELKPFPRP

8.63

-5.13

-3.82

LKPFPRPS

9.79

-3.38

-2.07

P25293

APTPHNTP

9.73

-3.46

-2.15

TPHNTPAS

11.17

-3.50

-2.19

P08018

GPPPRLPS

5.49

-7.54

-6.23

RAPRRPLS

6.62

-5.10

-3.79

QHPTRPNV

6.79

-4.90

-3.59

 


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