ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-28.PDB
Scoring matrix: NBP2_1YN8-28_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.92
Foldx random average score for Saccharomyces cerevisiae: 18.618

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 1092747
Proteins after disorder filtering: 3017
 Total fragments: 47770
Proteins after pattern filtering: 1483
 Total fragments: 8005
Proteins after MINT filtering: 7
 Total fragments: 94


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.92

2.19

0.00

Best peptides

RKPRFPRPGR

0.00

-6.20

-8.39

         
Interactors      
Q01389

KRSKPLPPQL

13.68

-5.00

-7.19

APTKPNPQGH

14.36

-5.51

-7.70

TPSRPVPPDS

14.46

-5.34

-7.53

P53933

RVAPPPLPNR

11.31

-5.38

-7.57

TRRRPPPPPI

12.62

-6.80

-8.99

RPPPPPIPST

12.93

-4.80

-6.99

P48562

NPYRPHHNMI

9.20

-8.10

-10.29

MRQAPKRPDA

12.19

-5.65

-7.84

LNPYRPHHNM

13.97

-4.91

-7.10

Q03497

KPSKPEAKSK

12.53

-5.36

-7.55

LPPIPPTKSK

13.56

-4.68

-6.87

FPSKNPLKNS

14.13

-5.84

-8.03

Q12469

LKPFPRPSDD

14.59

-4.18

-6.37

RLAPSAPATK

14.82

-4.98

-7.17

PFPRPSDDDY

14.94

-6.08

-8.27

P25293

PTPHNTPASV

17.75

-2.92

-5.11

P08018

RAPRRPLSTQ

9.48

-6.59

-8.78

PPPRLPSDKF

12.74

-6.70

-8.89

APRRPLSTQH

14.54

-6.45

-8.64

 


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