ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-23.PDB
Scoring matrix: NBP2_1YN8-23_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.89
Foldx random average score for Saccharomyces cerevisiae: 10.476

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2186688
Proteins after random average filtering: 5078
 Total fragments: 994558
Proteins after disorder filtering: 3181
 Total fragments: 45436
Proteins after pattern filtering: 1342
 Total fragments: 5468
Proteins after MINT filtering: 7
 Total fragments: 68


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.89

-1.56

0.00

Best peptides

RELKRWM

0.00

-5.54

-3.98

         
Interactors      
Q01389

RYPQTPS

7.58

-2.95

-1.39

EAPKPPA

7.72

-3.50

-1.94

SKPLPPQ

8.15

-2.84

-1.28

P53933

PPPLPNR

7.59

-4.73

-3.17

RRRPPPP

7.82

-4.35

-2.79

RPPPPPI

8.58

-1.72

-0.16

P48562

SPLNPYR

6.52

-3.76

-2.20

RGPMHPN

6.62

-4.94

-3.38

QFPRGPM

7.12

-3.97

-2.41

Q03497

PKVKPSK

6.25

-5.98

-4.42

FPSKNPL

7.00

-3.87

-2.31

EQPLPPI

7.39

-3.13

-1.57

Q12469

LKPFPRP

8.38

-3.96

-2.40

PFPRPSD

9.46

-3.03

-1.47

P25293

PTPHNTP

9.38

-4.37

-2.81

P08018

RAPRRPL

5.43

-5.22

-3.66

PPRLPSD

7.39

-5.95

-4.39

APRRPLS

8.16

-4.76

-3.20

 


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