ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-21.PDB
Scoring matrix: NBP2_1YN8-21_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 20.93
Foldx random average score for Saccharomyces cerevisiae: 18.691

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2171454
Proteins after random average filtering: 5078
 Total fragments: 1276917
Proteins after disorder filtering: 3048
 Total fragments: 51225
Proteins after pattern filtering: 1215
 Total fragments: 3301
Proteins after MINT filtering: 7
 Total fragments: 38


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

20.93

-0.10

0.00

Best peptides

EWRMGRPKMR

0.00

-5.17

-5.07

         
Interactors      
Q01389

IASPTSPKSL

14.59

-3.42

-3.32

RSKPLPPQLL

14.70

-2.37

-2.27

RRYPQTPSYY

16.53

-1.20

-1.10

P53933

VSYPGNPTSR

13.32

-2.75

-2.65

PPPPIPSTQK

17.32

-3.58

-3.48

P48562

PYRPHHNMIN

11.30

-4.89

-4.79

HVQPVAPKND

11.84

-4.01

-3.91

PLNPYRPHHN

13.55

-3.40

-3.30

Q03497

PIPPTKSKTS

13.54

-2.89

-2.79

FPSKNPLKNS

14.24

-3.73

-3.63

THAPTTPNRT

15.50

-1.80

-1.70

Q12469

RLAPSAPATK

15.77

-2.44

-2.34

PSAPATKNHD

17.56

-1.44

-1.34

P25293

PTPHNTPASV

18.62

-0.58

-0.48

P08018

TQHPTRPNVA

16.00

-2.07

-1.97

PPRLPSDKFS

16.81

-4.87

-4.77

RAPRRPLSTQ

17.45

-2.56

-2.46

 


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