ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-20.PDB
Scoring matrix: NBP2_1YN8-20_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.26
Foldx random average score for Saccharomyces cerevisiae: 17.814

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 957226
Proteins after disorder filtering: 3144
 Total fragments: 57706
Proteins after pattern filtering: 1496
 Total fragments: 7550
Proteins after MINT filtering: 6
 Total fragments: 86


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.26

-3.70

0.00

Best peptides

RRFRRGHHI

0.00

-6.66

-2.96

         
Interactors      
Q01389

RRYPQTPSY

9.99

-5.52

-1.82

RPVPPDSSY

11.72

-6.10

-2.40

KRSKPLPPQ

12.43

-5.94

-2.24

P53933

PPLPNRQLP

13.73

-5.92

-2.22

PPIPSTQKP

15.05

-5.91

-2.21

NDLPMELPH

15.87

-2.32

1.38

P48562

NPYRPHHNM

11.30

-10.63

-6.93

GQFPRGPMH

12.52

-2.45

1.25

QRTAPKPPI

13.94

-6.01

-2.31

Q03497

IPSRPAPKP

9.81

-9.33

-5.63

KQHKPKVKP

10.83

-7.64

-3.94

KKSFPSKNP

10.94

-6.47

-2.77

P08018

HPTRPNVAP

12.39

-7.57

-3.87

PRRPLSTQH

13.50

-4.11

-0.41

APRRPLSTQ

14.39

-6.48

-2.78

Q12469

LKPFPRPSD

12.88

-3.54

0.16

RLAPSAPAT

13.92

-4.42

-0.72

APSAPATKN

16.08

-4.65

-0.95

 


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