ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-16.PDB
Scoring matrix: NBP2_1YN8-16_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.88
Foldx random average score for Saccharomyces cerevisiae: 18.399

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 1208272
Proteins after disorder filtering: 3283
 Total fragments: 103169
Proteins after pattern filtering: 1613
 Total fragments: 12767
Proteins after MINT filtering: 7
 Total fragments: 150


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.88

0.65

0.00

Best peptides

RPPIPSRRH

0.00

-2.30

-2.95

         
Interactors      
Q01389

APTKPNPQG

12.32

-3.38

-4.03

KPLPPQLLS

12.97

-1.62

-2.27

SPTSPKSLD

13.50

-0.29

-0.94

P53933

RPPPPPIPS

11.24

-4.26

-4.91

YNDLPMELP

12.30

-2.45

-3.10

RRPPPPPIP

13.54

-0.97

-1.62

P48562

KPPISAPRA

6.76

-5.00

-5.65

RGPMHPNNS

9.68

-1.87

-2.52

LNPYRPHHN

10.40

-3.64

-4.29

Q03497

LPPIPPTKS

7.50

-4.33

-4.98

FPSKNPLKN

8.43

-4.68

-5.33

GKFIPSRPA

9.41

-2.02

-2.67

Q12469

LKPFPRPSD

11.80

-0.53

-1.18

APSAPATKN

13.94

-1.98

-2.63

PFPRPSDDD

14.34

-0.39

-1.04

P25293

NAPTPHNTP

14.61

0.73

0.08

APTPHNTPA

17.43

-0.76

-1.41

P08018

PPRLPSDKF

11.02

-2.47

-3.12

QHPTRPNVA

12.13

-0.23

-0.88

APRRPLSTQ

13.08

-2.65

-3.30

 


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