ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1YN8-15.PDB
Scoring matrix: NBP2_1YN8-15_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.08
Foldx random average score for Saccharomyces cerevisiae: 12.886

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 5078
 Total fragments: 2176532
Proteins after random average filtering: 5078
 Total fragments: 905384
Proteins after disorder filtering: 2728
 Total fragments: 25027
Proteins after pattern filtering: 1118
 Total fragments: 3510
Proteins after MINT filtering: 6
 Total fragments: 50


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.08

-0.12

0.00

Best peptides

RRFIIRKIR

0.00

-6.56

-6.44

         
Interactors      
Q01389

KRSKPLPPQ

9.63

-4.37

-4.25

RYPQTPSYY

9.97

-2.78

-2.66

RTEPSTPSR

11.41

-5.20

-5.08

P53933

PPPIPSTQK

10.94

-4.56

-4.44

RRPPPPPIP

12.05

-5.55

-5.43

RRRPPPPPI

12.10

-7.11

-6.99

P48562

NPYRPHHNM

8.56

-8.84

-8.72

RQAPKRPDA

8.76

-3.43

-3.31

KPPISAPRA

9.61

-5.87

-5.75

Q03497

HKPKVKPSK

6.71

-3.16

-3.04

FPSKNPLKN

10.76

-5.01

-4.89

LPPIPPTKS

10.84

-5.43

-5.31

P08018

APRRPLSTQ

8.62

-4.67

-4.55

RAPRRPLST

9.76

-7.35

-7.23

PPPRLPSDK

10.52

-4.92

-4.80

Q12469

LKPFPRPSD

9.91

-2.32

-2.20

RLAPSAPAT

12.47

-2.05

-1.93

 


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